Royals vs Mariners Prediction 9/17/25 MLB Picks Today
Seattle Mariners (83-68) vs. Kansas City Royals (75-76)
September 17, 2025 7:40 pm EDT
The Line: Kansas City Royals -113 / Seattle Mariners -107; Over/Under: 8.5
(Get latest betting odds)
The Seattle Mariners and the Kansas City Royals meet Wednesday in MLB action from Kauffman Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Royals vs Mariners Prediction.
Starting Pitching Matchup
The Seattle Mariners will send out Bryce Miller for the start here and Miller is 4-5 with a 5.59 ERA and 64 strikeouts this season. In his career, Miller is 0-0 with a 10.00 ERA and 7 strikeouts against the Royals. Kansas City will start Cole Ragans here and Ragans is 2-3 with a 5.18 ERA and 76 strikeouts this season. This will be Ragans’ second career start against the Mariners.
Seattle Mariners Recap
The Seattle Mariners come into this game looking to add on to their 12-5 win over the Royals from Tuesday’s series opener to sit at 83-68 this season. After this series, the Mariners will head on the road again for a massive division series against the Houston Astros.
Mariners Win Streak Hits Double-Digits
Jorge Polanco has 116 hits including 24 home runs and 72 RBIs while Cal Raleigh has 134 hits with 21 doubles, a team-high 54 home runs and 115 RBIs. Randy Arozarena has 137 hits with 30 doubles, 27 home runs, 73 RBIs and 28 stolen bases. Julio Rodriguez also has 165 hits with 30 doubles, 4 triples, 30 home runs, 91 RBIs and 27 stolen bases. J.P Crawford has 142 hits with 23 doubles, 10 home runs and 52 RBIs.
Why the Seattle Mariners will win
- The Mariners have won each of their last 10 games.
- The Royals have lost 10 of their last 11 home games against American League opponents that held a winning record.
- The Royals have failed to cover the run line in each of their last eight night games following a loss.
- The road team has covered the run line in each of the last four games between the Mariners and Royals.
Seattle Mariners Player Prop Facts
- Bryce Miller has recorded six or more strikeouts in each of his last four appearances against AL Central opponents that held a losing record.
- Jorge Polanco has recorded at least one Double in each of the Mariners’ last six games against opponents that held a losing record.
- Jorge Polanco has recorded at least one hit in each of the Mariners’ last 13 games.
- Bryce Miller has recorded a win in three of his last four road appearances against AL Central opponents.
- Julio Rodriguez has hit a home run in each of the Mariners’ last four games as underdogs against AL opponents.
Kansas City Royals Recap
The Kansas City Royals come into this game looking to bounce back from their loss at the hands of Seattle in Tuesday’s matchup to fall to 75-76 on the year. After this set, the Royals will take on the Toronto Blue Jays in a three-game weekend set at home.
Royals Lose 4 Of Their Last 5
Bobby Witt Jr. has 166 hits with 41 doubles and 36 stolen bases along with 6 triples, 22 home runs and 79 RBIs while Vinnie Pasquantino has 151 hits with 27 doubles, a triple, 30 home runs and 104 RBIs. Maikel Garcia’s added 161 hits with 36 doubles, 5 triples, 16 home runs and 70 RBIs and 23 stolen bases and Salvador Perez also has 34 doubles, 28 home runs and 89 RBIs but also has 115 strikeouts so far this season.
Why the Kansas City Royals will win
- The favorites have won each of the Mariners’ last nine games.
- The Mariners have lost each of their last five games against American League opponents following a road win.
- The Mariners have failed to cover the run line each of their last seven road games against American League opponents that held a losing record.
- The Royals have covered the run line in five of their last six night games against the Mariners following a loss.
Kansas City Royals Player Prop Facts
- Bobby Witt Jr. has recorded at least one hit in each of the Royals’ last 11 games against AL West opponents that held a winning record.
- Vinnie Pasquantino has hit a home run in four of the Royals’ last six games as favorites against AL West opponents.
Total Runs Facts
- Each of the last 10 games between the Mariners and Royals at Kauffman Stadium have gone OVER the total runs line.
- Seven of the Mariners’ last eight games against American League opponents have gone OVER the total runs line.
Royals vs Mariners Prediction
I’m on the Mariners here. I’m just not trying to get in front of this Seattle train right now, as the Mariners are just simply steam rolling anyone who gets in their path. The Royals are just the next unfortunate victim they’ve had to deal with. The Royals just look like a team that’s running out of gas, and I think Seattle adds to their misery here. Give me the Mariners.

