Angels vs Athletics Prediction 9/6/25 MLB Picks Today
Oakland Athletics (65-77) vs. LA Angels (66-75)
September 6, 2025 9:38 pm EDT
The Line: LA Angels -132 / Athletics +109; Over/Under: 9
(Get latest betting odds)
The Athletics and the Los Angeles Angels meet Saturday in MLB action from Busch Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Angels vs Athletics Prediction.
Starting Pitching Matchup
The Athletics will send out J.T. Ginn here and Ginn is 2-6 with a 5.17 ERA and 81 strikeouts this season. This will be Ginn’s second career start against the Angels. Yusei Kikuchi will get the nod for the Angels and is 6-10 with a 3.83 ERA and 162 strikeouts this season. In his last five starts against the Athletics, Kikuchi is 2-2 with a 4.56 ERA and 19 strikeouts.
Athletics Recap
The Athletics come into this game looking to build on their 10-4 win over the Angels from Friday’s matchup to sit at 65-77 on the year. After this series, the Athletics will head home for a set against the Boston Red Sox.
Athletics Looking To Build Momentum
Jacob Wilson has 130 hits, 20 doubles and a .315 batting average while Tyler Soderstrom has 137 hits with 28 doubles, 23 home runs and 81 RBIs this season. Brent Rooker has 149 hits with 37 doubles, 27 home runs and 80 RBIs but also has 133 strikeouts this season while Nick Kurtz has a team-high 28 home runs and 72 RBIs with 24 doubles. Shea Langeliers has 107 hits with 29 home runs and 65 RBIs while Lawrence Butler’s also chipped in 17 stolen bases and 29 doubles as part of his 117 hits as well as 18 home runs and 54 RBIs while also owning a team-high 159 strikeouts this season.
Why the Athletics will win
- The underdogs have won each of the Athletics’ last four games.
- The Angels have lost five of their last six games as favorites against AL West opponents.
- The Athletics have covered the run line in each of their last 12 Saturday games as road underdogs against American League opponents.
- The Angels have failed to cover the run line in eight of their last nine night games against American League opponents that held a losing record.
Athletics Player Prop Facts
- Brent Rooker has recorded a Double in three of the Athletics’ last four games as underdogs against the Angels.
- Shea Langeliers has hit a home run in three of his last four appearances against AL opponents that held a losing record.
- Shea Langeliers has recorded at least one hit in each of his last seven appearances with the Athletics as underdogs against the Angels.
- Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.314) this season.
Los Angeles Angels Recap
The Los Angeles Angels come into this game looking to bounce back from their loss at the hands of the Athletics on Friday to sit at 66-75 on the year. After this series, the Angels will square off in a series against the Minnesota Twins at home.
Angels Looking For Rebound Showing
Logan O’Hoppe has 85 hits including 19 home runs and 43 RBIs while Nolan Schanuel has 123 hits with 22 doubles, a triple, 10 home runs and 49 RBIs. Luis Rengifo has 15 doubles with his 110 hits and Taylor Ward also has 115 hits as well while Mike Trout’s added 20 home runs and 54 RBIs so far this season. Jorge Soler also has 12 doubles, 12 home runs and 34 RBIs, but also has 94 strikeouts so far this season. Jo Adell has 33 home runs and 90 RBIs. Ward has also chipped in 30 doubles, 30 home runs and 94 RBIs but has a team-high 152 strikeouts while Zach Neto has 29 doubles, 25 home runs, 60 RBIs and 24 stolen bases.
Why the Los Angeles Angels will win
- The Angels have won each of their last six games against AL West opponents following a home loss.
- The Athletics have lost each of their last four games against AL West opponents following a win.
- The Angels have covered the run line in each of their last six games against AL West opponents following a home loss.
- The Athletics have failed to cover the run line in four of their last five games against AL West opponents.
Los Angeles Angels Player Prop Facts
- Yusei Kikuchi has recorded five or more strikeouts in 14 of his last 15 appearances with his team as a home favorite against AL opponents.
- Zach Neto has hit a home run in four of the Angels’ last six games against AL West opponents that held a losing record.
- Luis Rengifo has recorded a hit in each of his last eight appearances against the Athletics.
- Yusei Kikuchi has recorded a win in five of his last six home appearances against opponents that held a losing record.
- Jo Adell ranks T8th in the league in Home Runs (33) this season.
Total Runs Facts
- Seven of the Athletics’ last eight games as underdogs have gone OVER the total runs line.
- Seven of the Angels’ last eight games as favorites against AL West opponents have gone OVER the total runs line.
Angels vs Athletics Prediction
I’m on the Athletics here. I get the case to be made for the Angels with how strong Kikuchi has been at home, but the thing here is that the Athletics just continue to wreck left-handed pitching. I think Kikuchi could be in trouble here as well. All the value for is on the Athletics here, so give me the A’s.

