LA Angels vs Minnesota Twins Prediction 9/20/26 MLB Picks Today

The Minnesota Twins and the Los Angeles Angels meet Sunday in MLB action from Angel Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Minnesota Twins vs. Los Angeles Angels prediction.

Starting Pitching Matchup

The Minnesota Twins will send out Dean Kremer for the start here and Kremer is 3-5 with a 5.35 ERA and 74 strikeouts this season. Ryan Johnson will start for the Angels here and is 5-8 with a 4.88 ERA and 70 strikeouts this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to rebound from a 6-5 loss at the hands of the Angels to sit at 72-83 this season. After this series, the Twins will head on the road for a series against the San Francisco Giants.

Twins Alternate Wins & Losses In 5 Straight

Luke Keaschall leads the Twins with a team-high 140 hits while adding 25 doubles, a triple, 9 home runs, and 45 RBIs so far this season. Brooks Lee has added 138 hits with 23 doubles, 3 triples, 23 home runs, and 81 RBIs, while Josh Bell leads Minnesota with a team-high 89 RBIs alongside 137 hits, 28 doubles, a triple, and 20 home runs on the year. Kody Clemens leads the Twins with a team-high 26 home runs along with 121 hits, 22 doubles, 7 triples, and 76 RBIs, Byron Buxton has contributed 94 hits with 18 doubles, a triple, 25 home runs, and 46 RBIs, and Victor Caratini has chipped in 69 hits with 9 doubles, 7 home runs, and 42 RBIs up to this point in the season.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to add on to their win over Minnesota last time out to sit at 60-95 this season. After this series, the Angels will head on the road for a series against the Athletics.

Angels Looking For Consistency

Zach Neto leads the Angels across the board with a team-high 142 hits, 26 home runs, and 74 RBIs while adding 29 doubles and 5 triples so far this season. Mike Trout has added 117 hits with 25 doubles, 21 home runs, and 53 RBIs, while Nolan Schanuel has contributed 108 hits with 22 doubles, 7 home runs, and 49 RBIs on the year. Oswald Peraza has logged 75 hits with 12 doubles, 2 triples, 7 home runs, and 25 RBIs, while Jorge Soler has chipped in 64 hits with 16 doubles, a triple, 12 home runs, and 49 RBIs for Los Angeles up to this point in the season.

Minnesota Twins @ Los Angeles Angels Betting Trends: September 20, 2026

• Probable Starting Pitcher: Ryan Johnson      Record this season: 5-8      ERA: 4.88
• Home Record: 3-3
• Last 5 against Twins: 0-0

Why the Los Angeles Angels will win

• The Twins have lost each of their last eight day games following an extra innings loss.
• The Angels have won four of their last six games as home underdogs against the Twins.
• The underdogs have covered the run line in five of the Twins’ last six games at Angel Stadium of Anaheim.
• The Twins have failed to cover the run line in 15 of their last 20 games as road favorites after playing the previous day.
• The Twins have trailed after 3 innings in each of their last six road day games.
• The Twins have trailed after 5 innings in eight of their last nine road day games.

• Probable Starting Pitcher: Dean Kremer      Record this season: 3-5      ERA: 5.35
• Road Record: 1-3
• Last 5 against Angels: 3-0

Why the Minnesota Twins will win

• The Angels have lost each of their last 10 day games after playing the previous day.
• The Twins have won four of their last five games following an extra innings loss.
• The Angels have failed to cover the run line in each of their last eight games against the Twins following a win.
• The Twins have covered the run line in each of their last 10 Sunday road games against AL West opponents.
• The Twins have led after 3 innings in five of their last six games against the Angels.
• The Twins have won the first inning in five of their last six games as road favorites against AL West opponents.
• The Twins have led after 5 innings in five of their last six day games against the Angels.

Total Runs Facts

• Each of the Angels’ last seven day games against AL Central opponents have gone UNDER the total runs line.
• Each of the Twins’ last four games as favorites against the Angels have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in nine of the Twins’ last 10 day games against AL opponents.
• There has been no run scored during the first inning in each of Ryan Johnson’s last four appearances as a starter.

Los Angeles Angels Player Prop Facts

• Moises Ballesteros has hit a home run in two of the Angels’ last three day games.
• Ryan Johnson has recorded five or more strikeouts in five of his last six home appearances against AL opponents.
• Ryan Johnson has recorded a win in each of his last three appearances against AL opponents.
• Mike Trout has recorded at least one hit in seven of his last eight appearances against the Twins.
• Mike Trout ranks 9th amongst qualified players for On Base Percentage (.380) this season.

Minnesota Twins Player Prop Facts

• Dean Kremer has recorded six or more strikeouts in four of his last five appearances in day games against AL teams that held a losing record.
• Dean Kremer has recorded a win in three of his four previous appearances against the Angels.
• Josh Bell has recorded at least one hit in each of his last 15 road appearances against AL West opponents that held a losing record.
• Ryan Kreidler has hit a home run in each of his last two appearances.

Matchup/League Facts

• The Angels rank 30th in the league for slugging percentage this season (.370).
• The Angels rank 30th in the league for strikeouts against this season (1480).
• The Twins rank 26th in the league for runs allowed this season (776).
• The Twins rank 25th in the league for walks this season (490).

Minnesota Twins vs. Los Angeles Angels Prediction

I’m backing the over in this game. I get the case to be made for either side in this game, but I don’t trust either one of these starting options when it comes to consistency, and this just feels like a high-scoring game across the board. These are also two of the least trustworthy bullpens in all of baseball in September, and I think this is going to see some runs. Give me the over.