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LA Angels vs Seattle Mariners Prediction 4/4/26 MLB Picks Today

Seattle Mariners (4-4) vs. LA Angels (3-5)
April 4, 2026 9:38 pm EDT
The Line: LA Angels +139 / Seattle Mariners -168; Over/Under: 9.5
(Get latest betting odds)

The Seattle Mariners and the Los Angeles Angels meet Saturday in MLB action from Angels Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Seattle Mariners vs. Los Angeles Angels prediction.

Starting Pitching Matchup

The Seattle Mariners will start Emerson Hancock here and Hancock is 1-0 with a 0.00 ERA and 9 strikeouts this season. This will be Hancock’s second career start against the Angels. Jack Kochanowicz will get hte start for the Angels here and Kochanowicz is 0-0 with a 11.25 ERA and 3 strikeouts this season. In his career, Kochanowicz is 0-2 with an 8.03 ERA and 11 strikeouts this season. 

Seattle Mariners Recap

The Seattle Mariners come into this game looking to add on to their 3-1 win over the Angels from Friday to sit at 4-4 this season. After this series, the Mariners will head on the road for a series against the Texas Rangers.

Mariners Snap Two-Game Skid

Entering Friday, Brendan Donovan has 10 hits with 2 doubles, 2 home runs and 4 RBIS while Luke Raley has 3 home runs and 6 RBIs this season. Cole Young’s added 8 hits with 2 doubles, a home run and 4 RBIs and Cal Raleigh has 4 hits with a double and 4 RBIs as well this season. Randy Arozarena has 6 hits with 3 doubles and 2 RBIs as well on the year.

Why the Seattle Mariners will win

  • The Mariners have won each of their last nine games against AL West opponents.
  • The Angels have lost five of their last six games.
  • The Mariners have covered the run line in each of their last six games against AL West opponents.
  • The Angels have failed to cover the run line in five of their last six games.

Seattle Mariners Player Prop Facts

  • Cal Raleigh has hit at least one home run in three of his last four road appearances against the Angels after playing the previous day.
  • Julio Rodriguez has recorded two or more hits in each of the Mariners’ last six Saturday games at Angel Stadium of Anaheim.
  • Luke Raley ranks T3rd in the league in Home Runs (3) this season.

Los Angeles Angels Recap

The Los Angeles Angels come into this game looking to bounce back from their loss at the hands of the Mariners on Friday to sit at 3-4 on the year. After this series, the Angels will take on the Atlanta Braves at home.

Angels Drop 5 Of Last 6

Going into Friday, Nolan Schanuel has 7 hits with a pair of homers and 5 RBIs while Mike Trout’s added 6 hits with 2 home runs and 3 RBIs this season. Zach Neto’s also added 6 hits with a double, 2 homers and 3 RBIs and Jo Adel has 7 hits with 2 RBIS as well this season. Oswald Peraza has 6 hits with a double, a home run and two RBIs and Jorge Soler has 4 hits with a double as well this season.

Why the Los Angeles Angels will win

  • The Angels have won seven of their last eight games as underdogs against AL West opponents following a home loss.
  • The Mariners have lost each of their last four games as favorites against the Angels following a road win.
  • The Angels have covered the run line in 15 of their last 16 games as underdogs against American League opponents following a home loss.
  • The Mariners have failed to cover the run line in eight of their last nine road games against American League opponents that held a losing record.

Los Angeles Angels Player Prop Facts

  • Jorge Soler has hit a home run in four of his last six home appearances against the Mariners after playing the previous day.
  • Mike Trout has recorded at least one hit in each of his last eight home appearances after playing the previous day.
  • Mike Trout ranks 8th amongst qualified players for On Base Percentage (.486) this season.

Total Runs Facts

  • Each of the Angels’ last five home games against AL West opponents have gone UNDER the total runs line.
  • Eight of the Mariners’ last 10 games as favorites have gone OVER the total runs line.

Seattle Mariners vs. Los Angeles Angels Prediction

I’m on the Mariners in this one. I just think that Seattle’s the better team and Kochanowicz has had some serious issues in his limited career sample size against the Mariners. The Angels can provide value in spots, but Hancock’s the better option and the Mariners have the better bullpen when it gets to the later stages of this game so give me Seattle here.

Chris Ruffolo's Free Pick: Seattle Mariners -168

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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