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Dodgers vs Phillies Prediction 9/16/25 MLB Picks Today

Philadelphia Phillies (90-61) vs. LA Dodgers (84-66)
September 16, 2025 10:10 pm EDT
The Line: LA Dodgers -123 / Philadelphia Phillies +101; Over/Under: 7.5
(Get latest betting odds)

The Philadelphia Phillies and the Los Angeles Dodgers meet Tuesday in MLB action from Dodger Stadium. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Dodgers vs Phillies Prediction.

Starting Pitching Matchup

The Philadelphia Phillies will send out Cristopher Sanchez for the start here and Sanchez is 13-5 with a 2.57 ERA and 192 strikeouts this season. In his career, Sanchez is 2-0 with a 3.57 ERA and 16 strikeouts against the Dodgers. Shohei Ohtani will get the start for the Dodgers here and is 1-1 with a 3.75 ERA and 49 strikeouts this season. This will be Ohtani’s first career start against the Phillies.

Philadelphia Phillies Recap

The Philadelphia Phillies come into this game looking to build on their 6-5 series-opening win over the Dodgers from Monday’s matchup to sit at 90-61 this season. After this series, the Phillies will take to the road for a series against the Arizona Diamondbacks.

Phillies Win 7 Of Last 8

Nick Castellanos has 131 hits with 27 doubles including 16 home runs and 66 RBIs while Kyle Schwarber has 136 hits with a team-high 52 home runs and 127 RBIs but also has a team-high 176 strikeouts as well on the year. Bryce Harper has 11 stolen bases, 31 doubles, 26 home runs and 72 RBIs. Trea Turner also has 179 hits with 7 triples, 15 home runs, 69 RBIs and a team-high 36 stolen bases. Max Kepler has 18 doubles and Bryson Stott has 20 doubles, 3 triples, 12 homers and 64 RBIs while Stott also has 23 stolen bases as well this season.

Why the Philadelphia Phillies will win

  • The Phillies have won each of their last eight night games after playing the previous day.
  • The Dodgers have lost each of their last four games as favorites after going to extra innings.
  • The Dodgers have failed to cover the run line in each of their last eight night games against NL East opponents.
  • The Phillies have covered the run line each of their last seven games against teams that held a winning record.

Philadelphia Phillies Player Prop Facts

  • Kyle Schwarber has hit a home run in each of the Phillies’ last three games.
  • Trea Turner has recorded at least one hit in each of his last 15 road appearances.
  • Kyle Schwarber ranks 2nd in the league in Home Runs (53) this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to bounce back from their loss at the hands of the Phillies to sit at 84-66 this season. After this series, the Dodgers will square off against the Giants in their series rematch from this past weekend.

Dodgers Looking For Bounce Back

Shohei Ohtani has 152 hits including 21 doubles, 49 home runs, 93 RBIs and 8 triples. Michael Conforto has 78 hits with 20 doubles while Teoscar Hernandez has 118 hits with 24 home runs, 27 doubles and 84 RBIs as well this season. Ohtani has a team-high 18 stolen bases while Max Muncy has 10 doubles but also has 73 strikeouts so far this season. Mookie Betts has also chipped in 18 home runs and 75 RBIs as well on the year. Freddie Freeman has also logged 152 hits with a team-high 39 doubles, 20 home runs and 82 RBIs. Andy Pages also has 145 hits with 23 doubles, 24 home runs and 80 RBIs as well this season.

Why the Los Angeles Dodgers will win

  • The Dodgers have won each of their last seven home games following an extra innings loss.
  • The Phillies have lost four of their last five games following an extra innings win.
  • The Phillies have failed to cover the run line in each of their last four games against National League opponents after going to extra innings.
  • The Dodgers have covered the run line in six of their last seven games after playing the previous day.

Los Angeles Dodgers Player Prop Facts

  • Mookie Betts has hit a home run in each of the Dodgers’ last three home games.
  • Shohei Ohtani has recorded six or more strikeouts in four of his last five appearances against NL East opponents.
  • Andy Pages has recorded at least one hit in each of the Dodgers’ last 12 games as favorites against NL East opponents.
  • Esteury Ruiz has recorded a Double in four of his last five appearances against NL East opponents that held a winning record.
  • Shohei Ohtani ranks 2nd amongst qualified players for Slugging Percentage (.608) this season.

Total Runs Facts

  • Each of the Phillies’ last seven games have gone OVER the total runs line.
  • Each of the Dodgers’ last six games following an extra innings loss have gone OVER the total runs line.

Dodgers vs Phillies Prediction

I’m on the over in this one. As good as Cristopher Sanchez has been for the Phillies this season, he has had some issues against the Dodgers in his career, and the Dodgers in September have been solid against left-handed pitching. On the other hand, Shohei Ohtani is solid, but the Phillies have cranked right-handed pitching in September, and if they don’t get to Ohtani, the Phillies can get to the Dodgers’ bullpen. I think we have some value on the over because of the name brand pitching matchup, so give me the over here.

Chris Ruffolo's Free Pick: Over 7.5

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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