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Mariners vs Nationals Prediction 5/29/25 MLB Picks Today

Washington Nationals (25-30) vs. Seattle Mariners (30-24)
May 29, 2025 9:40 pm EDT
The Line: Seattle Mariners -112 / Washington Nationals -108; Over/Under: 7.5
(Get latest betting odds)

The Washington Nationals and the Seattle Mariners meet Thursday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Mariners vs Nationals Prediction.

Starting Pitching Matchup

The Washington Nationals will send MacKenzie Gore out for the start, and Gore is 2-5 with a 3.47 ERA and 93 strikeouts this season. This will be Gore’s second career start against the Mariners. The Seattle Mariners will send out Emerson Hancock for the start here, and Hancock is 2-2 with a 5.95 ERA and 28 strikeouts this season. This will be Hancock’s first career start against the Nationals.

Washington Nationals Recap

The Washington Nationals will look to build on their 9-0 win over the Mariners in Wednesday’s matchup to improve to 25-30 on the year. After this series, the Nationals will head on the road for a series against the Arizona Diamondbacks.

Nationals Looking To Win Rubber Match

Keibert Ruiz has 49 hits with 9 doubles and a pair of home runs with 20 RBIs, while James Wood has 60 hits with 14 doubles and a team-high 15 home runs, along with 40 RBIs and 8 stolen bases while also putting up 65 strikeouts. Nathaniel Lowe has 46 hits with 9 doubles and 34 RBIs, along with 8 home runs and 63 strikeouts. CJ Abrams has 8 home runs and 19 RBIs along with 10 doubles and 9 stolen bases, while Luis Garcia Jr. has 10 doubles and 7 stolen bases of his own this season. Dylan Crews has also logged a team-high 11 stolen bases this season.

Why the Washington Nationals will win

  • The Mariners have lost each of their last four games as favorites after playing the previous day.
  • The Nationals have won each of their last four games as road underdogs after playing the previous day.
  • The Mariners have failed to cover the run line in each of their last six games as favorites after playing the previous day.
  • The Nationals have covered the run line in each of their last six games as underdogs after playing the previous day.

Washington Nationals Player Prop Facts

  • Luis Garcia has hit a home run in three of his last five road appearances after playing the previous day.
  • Luis Garcia has recorded at least one RBI in five of his last six road appearances after playing the previous day.
  • MacKenzie Gore has recorded a win in three of his last four appearances in night games against AL teams that held a winning record.
  • Luis Garcia has scored at least one run in four of his last five road appearances after playing the previous day.
  • MacKenzie Gore has recorded nine strikeouts in three of his last four appearances.
  • Amed Rosario has recorded at least one hit in each of his last nine appearances with the Nationals as underdogs.
  • Amed Rosario has recorded a Double in four of his last five appearances against opponents that held a winning record.
  • Amed Rosario has recorded at least one Single in seven of his last eight appearances in night games.
  • MacKenzie Gore ranks 1st in the league for total Strikeouts (93) this season.

Seattle Mariners Recap

The Seattle Mariners come into this game looking to bounce back from a loss to the Nationals on Wednesday to drop to 30-24 this season. After this series, the Mariners will square off against the Minnesota Twins at home.

Mariners Looking To Get Back On Track

Jorge Polanco has 37 hits, including 10 home runs and 30 RBIs, while Cal Raleigh has 51 hits with 10 doubles, a team-high 19 home runs, and 37 RBIs. Randy Arozarena has 42 hits with 11 doubles, 6 home runs, 21 RBIs, and 9 stolen bases. Julio Rodriguez also has 52 hits with a pair of triples, 10 home runs, 32 RBIs, and 6 stolen bases. Dylan Moore has 8 homers and 8 stolen bases as well this season. Rowdy Tellez has also added 8 home runs and 23 RBIs, while J.P. Crawford has 46 hits with 5 doubles, 4 home runs, and 20 RBIs.

Why the Seattle Mariners will win

  • The Mariners have won each of their last eight home games against National League opponents following a loss.
  • The Nationals have lost 15 of their last 16 night games against American League opponents following a road win.
  • The Nationals have failed to cover the run line in 15 of their last 16 night games against American League opponents following a road win.
  • The Mariners have covered the run line in each of their last seven night games against National League opponents following a home loss.

Seattle Mariners Player Prop Facts

  • Cal Raleigh has recorded at least one RBI in five of the Mariners’ last six games against NL opponents.
  • J.P. Crawford has scored at least one run in seven of the Mariners’ last eight night games against NL East opponents that held a losing record.
  • J.P. Crawford has recorded at least one Single in eight of the Mariners’ last nine games as favorites against NL opponents.
  • Jorge Polanco has hit at least one home run in three of his last four appearances in night games against NL teams that held a losing record.
  • Victor Robles has recorded at least one hit in each of his last eight appearances.
  • Cal Raleigh ranks 2nd in the league in Home Runs (19) this season.

Total Runs Facts

  • Each of the Mariners’ last 10 games as home favorites have gone OVER the total runs line.
  • Seven of the Nationals’ last eight games as underdogs against American League opponents have gone OVER the total runs line.

Mariners vs Nationals Prediction

I’m on the Nationals here. I just think that the Nationals have a clear edge in starting pitching. While I’m not always sold on their relief pitching, I think that the Nationals can carry over some of their success at the plate from Wednesday’s win against Emerson Hancock, who has really struggled at home this season. Give me Washington in this one.

Chris Ruffolo's Free Pick: Washington Nationals -108

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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