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Mariners vs Orioles Prediction 6/5/25 MLB Picks Today

Baltimore Orioles (24-36) vs. Seattle Mariners (32-28)
June 5, 2025 3:40 pm EDT
The Line: Seattle Mariners -170 / Baltimore Orioles 142; Over/Under: 7.5
(Get latest betting odds)

The Baltimore Orioles and Seattle Mariners meet Thursday in MLB action at T-Mobile Park. Here’s a Mariners vs Orioles Prediction. This article will include a Mariners vs Orioles Pick.

Baltimore Orioles Betting Preview

The Baltimore Orioles are 24-36 on the year and play the Athletics, Tigers, and Angels next. The Baltimore Orioles are batting .237 on the season, have a .303 OBP, and a .386 slugging percentage. The Baltimore Orioles pitching staff has a 5.14 ERA and a 1.44 WHIP. Ryan O’Hearn leads the Baltimore Orioles with 58 hits and 23 RBI, while Gunnar Henderson and Jackson Holliday have combined for 108 hits and 41 RBI.

Zach Eflin gets the ball for the Baltimore Orioles, and he is 4-2 with a 4.46 ERA and 24 strikeouts this season. Eflin is 1-0 with a 4.91 ERA and 11 strikeouts in his career against the Seattle Mariners.

Seattle Mariners Betting Preview

The Seattle Mariners are 32-28 on the year and play the Angels, Diamondbacks, and Guardians next. The Seattle Mariners are batting .235 on the season, have a .320 OBP, and a .414 slugging percentage. The Seattle Mariners’ pitching staff has a 3.87 ERA and a 1.33 WHIP. Julio Rodriguez leads the Seattle Mariners with 60 hits and 32 RBI, while Cal Raleigh and J.P. Crawford have combined for 114 hits and 68 RBI.

Bryan Woo gets the ball for the Seattle Mariners, and he is 5-2 with a 2.82 ERA and 63 strikeouts this season. This will be Woo’s first career game against the Baltimore Orioles.

Why the Seattle Mariners will win

  • The Orioles have lost each of their last seven day games against American League opponents that held a winning record.
  • The Mariners have won each of their last eight Thursday games against the Orioles.
  • The Orioles have failed to cover the run line in nine of their last 10 day games against American League opponents that held a winning record.
  • The Mariners have covered the run line in each of their last six Thursday day games against the Orioles.
  • The Mariners have led after 5 innings in four of their last five day games at T-Mobile Park against AL East opponents.
  • The Mariners have led after 3 innings in seven of their last eight Thursday day games as favorites.

Why the Baltimore Orioles will win

  • The Orioles have won each of their last five games as underdogs against the Mariners.
  • The Mariners have lost each of their last eight games against AL East opponents that held a losing record.
  • The Mariners have failed to cover the run line in each of their last nine games as favorites after playing the previous day.
  • The underdogs have covered the run line in each of the Mariners’ last seven games.
  • The Orioles have led after 3 innings in four of their last five day games against opponents that held a winning record.
  • The Orioles have led after 5 innings in each of their last four games as underdogs.

Seattle Mariners Player Prop Facts

  • Victor Robles has hit a home run in three of his last four appearances with his team as a home favorite against AL East opponents.
  • Cal Raleigh has recorded a Double in three of the Mariners’ last four games against AL opponents that held a losing record.
  • Victor Robles has recorded at least one hit in each of his last 10 appearances in day games.
  • Julio Rodriguez has recorded at least one Single in each of the Mariners’ last six games against AL opponents.
  • Victor Robles has recorded at least one RBI in each of his last four appearances in day games against teams that held a losing record.
  • Victor Robles has scored at least one run in each of his last five appearances with his team as a home favorite against AL East opponents.
  • Cal Raleigh ranks T1st in the league in Home Runs (23) this season.

Baltimore Orioles Player Prop Facts

  • Gunnar Henderson has hit a home run in three of the Orioles’ last four day games against AL West opponents that held a winning record.
  • Zach Eflin has recorded a win in three of his last four road appearances.
  • Adley Rutschman has scored at least one run in each of the Orioles’ last four games as underdogs against AL West opponents.
  • Zach Eflin has recorded five strikeouts in each of his last four appearances against AL West opponents.
  • Dylan Carlson has recorded at least one hit in each of the Orioles’ last seven games against AL opponents.
  • Ryan Mountcastle has recorded at least one Double in each of his last six Thursday day appearances.
  • Ryan O’Hearn has recorded at least one Single in 13 of his last 14 appearances with the Orioles as road underdogs against AL opponents.
  • Ryan Mountcastle has recorded an RBI in four of his last five appearances with the Orioles as underdogs against AL opponents.
  • Ryan O’Hearn ranks 4th amongst qualified players for Batting Average (.328) this season.

Mariners vs Orioles Prediction

Don’t look now, but the Orioles have won five straight games and are quietly looking like an MLB team for the first time this season. I still lean Mariners in this spot. Eflin has been hittable this season, which includes allowing 24 hits and 14 earned runs in his last 22.1 innings. Woo looks like an all-star with his 2.82 ERA and 0.95 WHIP, and he’s allowed 34 hits and 11 runs in his last 38.1 innings. In 26 home innings, Woo has a 1.73 ERA and a .200 allowed batting average. The Mariners have had some tough recent losses, but they have a clear edge on the mound. If the Mariners can’t stop the bleeding here, something is wrong. Give me the home team.

Randy Chambers's Free Pick: Seattle Mariners -170

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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