Marlins vs Diamondbacks Prediction 4/16/25 MLB Picks Today

The Arizona Diamondbacks and the Miami Marlins meet Wednesday in MLB action from LoanDepot Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Marlins vs Diamondbacks Prediction.

Starting Pitching Matchup

The Arizona Diamondbacks will send out Brandon Pfaadt for the start here, and Pfaadt is 2-1 with a 3.50 ERA and 12 strikeouts this season. In his career, Pfaadt is 1-1 with an 8.71 ERA and 7 strikeouts against the Marlins. Max Meyer will get the start for Miami here and is 1-1 with a 2.00 ERA and 19 strikeouts this season. This will be Meyer’s first career start against Arizona.

Arizona Diamondbacks Recap

The Arizona Diamondbacks come into this game looking to keep the ball rolling after a 10-4 win over the Marlins in Tuesday’s series opener to improve to 10-7 on the year. After this series, the Diamondbacks will head on the road for a weekend set against the Chicago Cubs.

Diamondbacks Looking For Third Straight Series Win

Corbin Carroll has a team-high 23 hits with 6 home runs, 15 RBIs, and 7 doubles, while Josh Naylor has 21 hits with 6 doubles as well this season. Eugenio Suarez has also added 5 home runs and 11 RBIs, while Geraldo Perdomo has a team-high 16 RBIs. Naylor has also chipped in a team-high 4 stolen bases as well up to this point in the year, while Suarez has the unfortunate distinction of leading the Diamondbacks with 21 strikeouts so far this season.

Why the Arizona Diamondbacks will win

• The Diamondbacks have won each of their last 15 Wednesday games.
• The Marlins have lost 10 of their last 11 night games against NL West opponents that held a winning record.
• The road team has covered the run line in each of the last nine games between the Diamondbacks and Marlins.
• The Marlins have failed to cover the run line in 10 of their last 11 night games against NL West opponents that held a winning record.

Arizona Diamondbacks Player Prop Facts

• Corbin Carroll has recorded a Double in four of the Diamondbacks’ last five games against NL opponents.
• Corbin Carroll has recorded at least one RBI in each of the Diamondbacks’ last six Wednesday games as favorites.
• Brandon Pfaadt has recorded a win in each of his last four appearances with the Diamondbacks as road favorites.
• Gabriel Moreno has recorded at least one Single in nine of his last 10 appearances with the Diamondbacks as road favorites against NL opponents.
• Corbin Carroll has scored at least one run in each of the Diamondbacks’ last 11 Wednesday games as favorites.
• Lourdes Gurriel Jr. has recorded at least one hit in each of his 12 previous appearances at LoanDepot Park.
• Ketel Marte has hit a home run in three of his last four road appearances with the Diamondbacks against NL opponents.
• Corbin Carroll ranks T2nd in the league in Home Runs (6) this season.

Miami Marlins Recap

The Miami Marlins come into this game looking to bounce back after starting the series on the wrong foot and ending up at 8-8 on the year as a result. After this set, the Marlins will head on the road for a division series against the Philadelphia Phillies.

Marlins Looking To Rebound

Xavier Edwards leads the Marlins with 20 hits, including 3 doubles and a team-high 6 stolen bases, while Graham Pauley has 4 doubles. Otto Lopez has 14 hits with 4 doubles and a pair of home runs with 8 RBIs, and Matt Mervis has a team-high 5 home runs and 11 RBIs so far this year. Kyle Stowers has 16 hits with 3 doubles, a triple, a home run, and 10 RBIs, but also leads the Marlins with 18 strikeouts so far this season. Griffin Conine’s also chipped in 16 hits with a team-high 5 doubles as well this season.

Why the Miami Marlins will win

• The Marlins have won four of their last five games as underdogs against NL West opponents following a loss.
• The Diamondbacks have lost three of their last four games as favorites against NL East opponents following a win.
• The Marlins have covered the run line in seven of their last eight night games following a loss.
• The Diamondbacks have failed to cover the run line in four of their last five night games against National League opponents following a win.

Miami Marlins Player Prop Facts

• Otto Lopez has hit a home run in four of the Marlins’ last 16 night games.
• Otto Lopez has recorded a Double in each of his last four appearances with the Marlins as underdogs against NL opponents.
• Otto Lopez has recorded at least one RBI in three of the Marlins’ last four night games against NL West opponents that held a winning record.
• Otto Lopez has scored at least one run in each of the Marlins’ last five home games against NL West opponents.
• Jesus Sanchez has recorded at least one Single in each of his last four appearances against opponents that held a winning record.
• Otto Lopez has recorded at least one hit in each of the Marlins’ last 11 games against NL West opponents that held a winning record.
• Xavier Edwards ranks T4th in the league in Steals (6) this season.

Total Runs Facts

• Eight of the Marlins’ last nine home games against NL West opponents have gone OVER the total runs line.
• Seven of the Diamondbacks’ last eight night games against NL East opponents have gone OVER the total runs line.

Marlins vs Diamondbacks Prediction

I’m on the over here. I just can’t get there with Arizona at this price, as I still have trust issues with Brandon Pfaadt. He’s had issues against the Marlins in limited action in his career, and you could argue this is the best the Marlins’ lineup has looked from a production standpoint in some time, early on this year. On the other side, Meyer faces a tough Arizona lineup that can produce runs as well, but the Miami bullpen has been problematic as well this season, so I think the Fish will allow a few runs here as well. Give me the over.