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Marlins vs Giants Prediction 4/25/26 MLB Picks Today

Miami Marlins (13-13) vs. San Francisco Giants (11-15)
April 25, 2026 4:05 pm EDT
The Line: San Francisco Giants 0.0001 / Miami Marlins 0.0001; Over/Under: 0.0001
(Get latest betting odds)

In this article, we will formulate a Marlins vs Giants Prediction for this MLB matchup on Saturday, April 25th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

San Francisco Giants Preview

The San Francisco Giants have a 11-15 record this season and are sitting in the fourth place of the NL West. They have a 5-9 home record and are coming off a 4-9 home loss against the Marlins. Their previous three games were a 0-3 loss, a 3-0 win and a 3-1 win at home against the Dodgers.

The Giants have a .247 batting average this season, .288 OBP and .355 Slugging percentage. San Francisco’s pitching staff has a 3.97 ERA and 1.32 WHIP. Luis Arraez is the team’s best hitter with a .320 batting average. Heliot Ramos leads the team in RBI with 13, and Willy Adames adds a team‑high 3 home runs.

Robbie Ray (L) is the projected starting pitcher for the Giants, and he has a 2-3 record, 2.86 ERA and 1.09 WHIP.

Miami Marlins Preview

The Miami Marlins have a 13-13 record this season and are sitting in the second place of the NL East. They have a 3-7 away record and are coming off a 9-4 road win against the Giants. Their previous three games were a 4-1 win, a 3-5 loss and a 5-3 win at home against the Cardinals.

The Marlins have a .264 batting average this season, .339 OBP and .400 Slugging percentage. Miami’s pitching staff has a 3.89 ERA and 1.24 WHIP. Xavier Edwards is the team’s best hitter with a .347 batting average. Liam Hicks leads the team in RBI with 24, also adding a team‑high 5 home runs.

Eury Perez (R) is the projected starting pitcher for the Marlins, and he has a 2-1 record, 4.15 ERA and 1.35 WHIP.

Miami Marlins @ San Francisco Giants Betting Trends: April 25, 2026

 

  • Probable Starting Pitcher: Robbie Ray      Record this season: 2-3      ERA: 2.86
  • Home Record: 2-1
  • Last 5 against Marlins: 2-2

Why the San Francisco Giants will win

  • The Giants have won 12 of their last 14 day games against the Marlins following a loss.
  • The Marlins have lost five of their last six road games after playing the previous day.
  • The Marlins have failed to cover the run line in seven of their last eight day games against National League opponents that held a losing record.
  • The favorites have covered the run line in four of the Marlins’ last five games.
  • The Marlins have trailed after 3 innings in each of their last four road day games.
  • The Marlins have lost the first inning in three of their last four day games against opponents that held a losing record.
  • The Marlins have trailed after 5 innings in each of their last four road day games.

 

  • Probable Starting Pitcher: Eury Perez      Record this season: 2-1      ERA: 4.15
  • Road Record: 0-1
  • Last 5 against Giants: –

Why the Miami Marlins will win

  • The Giants have lost each of their last 10 games as favorites against National League opponents following a home loss.
  • The Marlins have won each of their last 11 road games against NL West opponents.
  • The Giants have failed to cover the run line in each of their last 14 games as favorites against National League opponents following a home loss.
  • The Marlins have covered the run line in each of their last 11 road games against NL West opponents following a win.
  • The Giants have trailed after 5 innings in each of their last four games as home favorites against NL East opponents.
  • The Giants have trailed after 3 innings in each of their last four games as home favorites against NL East opponents.
  • The Marlins have won the first inning in four of their last five games as underdogs against NL West opponents.

Total Runs Facts

  • Each of the Marlins’ last nine road games against NL West opponents have gone OVER the total runs line.
  • Six of the Giants’ last seven day games as favorites have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Giants’ last five day games at Oracle Park.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Marlins’ last six games as underdogs against NL West opponents.

San Francisco Giants Player Prop Facts

  • Matt Chapman has recorded at least one hit in each of the Giants’ last nine games as favorites.
  • Adrian Houser has hit a home run in each of his two previous appearances against the Marlins.
  • Luis Arraez ranks T9th amongst qualified players for Batting Average (.320) this season.

Miami Marlins Player Prop Facts

  • Otto Lopez has hit a home run in two of the Marlins’ last three games as road underdogs against NL West opponents.
  • Agustin Ramirez has recorded at least one hit in each of the Marlins’ last 13 road games against NL West opponents.
  • Xavier Edwards ranks T2nd in the league in Hits (34) this season.

Matchup/League Facts

  • The Giants rank 30th in the league for runs scored this season (85).
  • The Giants rank 30th in the league for RBIs this season (81).
  • The Marlins rank 2nd in the league for triples this season (8).
  • The Marlins rank 2nd in the league for steals this season (29).

Marlins vs Giants Prediction

The Marlins are 7-2 in their last 9 meetings against the Giants and have won their last 6 visits in San Francisco.

In this Marlins vs Giants Prediction, the Giants are coming as -119 home favorites. The Marlins won the opening game of this series and are now 4-1 in their last 5 games. Ray has been excellent for the Giants and both teams are top-6 in bullpen ERA and have both been struggling to hit the opposing starter throw hand, as the Giants already have the worst offense in baseball and average just 2.7 runs/9 against righties. The Marlins also struggle against lefties, with 3.5 runs/9 so I expect a low-scoring affair. Take the under 7.5 in this one.

Nikos Lagouretos's Free Pick: Under 7.5

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