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Mets vs Cubs Prediction 6/22/26 MLB Picks Today

Chicago Cubs (40-37) vs. NY Mets (34-43)
June 22, 2026 7:10 pm EDT
The Line: NY Mets 101 / Chicago Cubs -122; Over/Under: 8.5
(Get latest betting odds)

In this article we will formulate a Mets vs Cubs prediction for this MLB game on Monday, June 22nd at Citi Field in Queens, New York. Let’s take a look at the prediction for this MLB matchup. 

New York Mets Betting Preview

The New York Mets are 34-43 this year after they lost two out of three against the Phillies by scores of 6-4, 3-15, and 2-6. In game three, New York cut the deficit to 6-2 in the sixth inning, but couldn’t find anymore offense in the loss. The Mets recorded six hits and they committed one error in the game, while they were led by Benge, who went 1-3 with one home run and one RBI. Peterson allowed six hits and four earned runs over 4.0 innings for the loss, while Warren allowed one earned run in relief. Prior to that series, New York lost two out of three against the Reds, but did win two out of three against the Braves before that. 

This season, New York has a 4.08 ERA with a 1.28 WHIP and a .233 opponent batting average, while they have scored 311 runs with a .232 batting average and a .297 on base percentage. Juan Soto has led the Mets with 17 home runs and 38 RBIs, while Bo Bichette has added eight home runs and 42 RBIs. The projected starting pitcher for New York is Kodai Senga, who is 0-5 with a 9.00 ERA and a 1.88 WHIP over 24.0 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 40-37 this year after they split two games with the Blue Jays by scores of 16-2 and 6-8. In game two, Chicago led 5-0 in the sixth inning and they were cruising to the win, but the bullpen fell apart for the tough loss. The Cubs recorded nine hits in the game and they were led by Shaw, who went 1-5 with one home run and three RBIs. Rea allowed three hits and zero earned runs over 5.1 innings, while Webb allowed three earned runs for the loss. Prior to that series, Chicago won two out of three against the Rockies and two out of three against the Giants. 

This season, Chicago has a 4.28 ERA with a 1.24 WHIP and a .240 opponent batting average, while they have scored 366 runs with a .244 batting average and a .337 on base percentage. Michael Busch has led the Cubs with eight home runs and 42 RBIs, while Ian Happ has added 16 home runs and 37 RBIs. The projected starting pitcher for Chicago is Shota Imanaga, who is 4-6 with a 4.26 ERA and a 1.06 WHIP over 86.2 innings pitched this year. 

Why the New York Mets will win

  • The Mets have won each of their last seven night games against the Cubs following a loss.
  • The Cubs have lost each of their last four games as road favorites against National League opponents following a home loss.
  • The Mets have covered the run line in each of their last seven night games against the Cubs following a loss.
  • The Cubs have failed to cover the run line in each of their last seven road games following a home loss.
  • The Mets have won the first inning in three of their last four home games.
  • The Cubs have trailed after 5 innings in eight of their last nine Monday night road games.

Why the Chicago Cubs will win

  • The Cubs have won each of their last eight games against NL East opponents that held a losing record.
  • The Mets have lost each of their last 13 games as underdogs against National League opponents following a road loss.
  • The Mets have failed to cover the run line in nine of their last 10 home games against NL Central opponents that held a winning record.
  • The Cubs have covered the run line in seven of their last eight games against NL East opponents that held a losing record.
  • The Mets have lost the first inning in four of their last five night games.
  • The Cubs have led after 5 innings in seven of their last eight games as favorites.
  • The Cubs have led after 3 innings in each of their last six games as favorites.

Total Runs Facts

  • Nine of the Cubs’ last 10 night games against National League opponents have gone UNDER the total runs line.
  • Three of the last four games between the Cubs and Mets at Citi Field have gone OVER the total runs line.
  • There has been at least one run scored in the first inning in each of the Mets’ last seven night games.
  • There has been no run scored during the first inning in eight of the Cubs’ last nine games against NL East opponents.

New York Mets Player Prop Facts

  • Juan Soto has hit a home run in four of his last six appearances against NL Central opponents that held a winning record.
  • Kodai Senga has recorded five or more strikeouts in 10 of his last 12 home appearances against opponents that held a winning record.
  • Francisco Lindor has recorded at least one hit in each of his last nine home appearances against opponents that held a winning record.
  • Juan Soto ranks 5th amongst qualified players for Slugging Percentage (.575) this season.

Chicago Cubs Player Prop Facts

  • Seiya Suzuki has hit a home run in each of the Cubs’ last three games against NL East opponents that held a losing record.
  • Shota Imanaga has recorded six or more strikeouts in four of his last five road appearances.
  • Alex Bregman has recorded at least one hit in 22 of his last 23 road appearances.
  • Shota Imanaga has recorded a win in six of his last seven appearances against NL East opponents that held a losing record.
  • Pete Crow-Armstrong is one of only two players to record 10+ Home Runs and 4+ Triples this season.

Matchup/League Facts

  • The Mets rank 30th in the league for doubles this season (95).
  • The Mets rank 29th in the league for on-base percentage this season (.297).
  • The Cubs rank 1st in the league for walks this season (338).
  • The Cubs rank 29th in the league for home runs allowed this season (113).

Mets vs Cubs Prediction 

New York is coming off of another series loss over the weekend and they have allowed 25 runs in their last three games. The Mets are 18-18 at home this year, while the Cubs are 17-20 on the road. Chicago has split their last four games and they have scored 5+ runs in four of their last five. The Cubs are starting Imanaga, who has allowed 5+ earned runs in three of his last five starts, while Senga has allowed 3+ earned runs in three straight outings. Take the over here. 

David Racey's Free Pick: Over 8.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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