Minnesota Twins vs LA Dodgers Prediction 6/22/26 MLB Picks Today

The Los Angeles Dodgers and the Minnesota Twins meet Monday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Dodgers vs. Minnesota Twins prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will send out Eric Lauer for the start here and Lauer is 2-5 with a 5.37 ERA and 40 strikeouts this season. Zebby Matthews will start for Minnesota here and is 3-4 with a 4.78 ERA and 34 strikeouts this season.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to shake off a 12-1 loss at the hands of the Baltimore Orioles on Sunday to slip to 49-29 this season. After this series, the Dodgers will head on the road for a series against the San Diego Padres.

Dodgers Drop Back-To-Back Games

Andy Pages has 80 hits with 18 doubles, 15 home runs and 57 RBIs while Teoscar Hernandez has 50 hits with 8 doubles, 7 home runs and 31 RBIs. Shohei Ohtani has 78 hits with 15 doubles, 16 home runs and 43 RBIs and Freddie Freeman has 77 hits with 17 doubles, a triple, 12 home runs and 40 RBIs this season. Will Smith has 6 home runs and 23 RBIs as well this season. Max Muncy’s added 61 hits with 9 doubles, 16 home runs and 31 RBIs and Kyle Tucker has 64 hits with 16 doubles, 6 home runs and 40 RBIs this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to add on to their 4-2 win over the Arizona Diamondbacks last time out to sit at 38-41 this season. After this series, the Twins will take on the Colorado Rockies in a series at home.

Twins Win 7 Of Last 9

Byron Buxton has 76 hits with 13 doubles, a triple, 24 home runs and 40 RBIs while Josh Bell’s added 69 hits with 15 doubles, 9 home runs and 48 RBIs. Luke Keaschall has 66 hits with 12 doubles, 2 homers and 24 RBIs. Brooks Lee has 12 home runs with 44 RBIs and Victor Caratini has 29 RBIs while Kody Clemens has 57 hits with 15 doubles, 2 triples, 11 home runs and 29 RBIs this season.

Los Angeles Dodgers @ Minnesota Twins Betting Trends: June 22, 2026

• Probable Starting Pitcher: Zebby Matthews      Record this season: 3-4      ERA: 4.78
• Home Record: 2-1
• Last 5 against Dodgers: –

Why the Minnesota Twins will win

• The Twins have won five of their last six games as underdogs.
• The Dodgers have lost three of their last four games as favorites against AL Central opponents.
• The Dodgers have failed to cover the run line in each of their last seven games.
• The Twins have covered the run line in each of their last eight Monday night games.
• The Twins have led after 3 innings in each of their last four night games.
• The Twins have won the first inning in three of their last four night games.
• The Twins have led after 5 innings in each of their last eight Monday night games.

• Probable Starting Pitcher: Eric Lauer      Record this season: 2-5      ERA: 5.37
• Road Record: 0-3
• Last 5 against Twins: 1-3

Why the Los Angeles Dodgers will win

• The Dodgers have won each of their last nine games against AL Central opponents following a home loss.
• The Twins have lost each of their last six games against the Dodgers following a win.
• The road team has covered the run line in each of the Dodgers’ last six games.
• The Twins have failed to cover the run line in each of their last four night games against NL West opponents following a win.
• The Dodgers have led after 3 innings in each of their last five road games against American League opponents.
• The Dodgers have won the first inning in three of their last four games against AL Central opponents that held a losing record.
• The Dodgers have led after 5 innings in 11 of their last 12 games as road favorites.

Total Runs Facts

• Ten of the Twins’ last 11 night games as underdogs have gone OVER the total runs line.
• Five of the Dodgers’ last six road games have gone OVER the total runs line.
• There has been at least one run scored in the first inning in each of Eric Lauer’s last six appearances as a starter.
• There has been no run scored during the first inning in five of the Twins’ last six home games against NL West opponents.

Minnesota Twins Player Prop Facts

• Byron Buxton has hit at least one home run in three of his last four home appearances against NL opponents.
• Byron Buxton has recorded at least one hit in each of his last nine home appearances against NL opponents that held a winning record.
• Byron Buxton ranks 3rd in the league in Home Runs (24) this season.

Los Angeles Dodgers Player Prop Facts

• Shohei Ohtani has hit a home run in four of his last five appearances in night games.
• Eric Lauer has recorded four or more strikeouts in eight of his nine previous appearances against AL Central opponents that held a losing record.
• Mookie Betts has recorded at least one hit in each of his last 10 road appearances against the Twins after playing the previous day.
• Eric Lauer has recorded a win in three of his last four appearances in night games against teams that held a losing record.
• Shohei Ohtani ranks 3rd amongst qualified players for On Base Percentage (.418) this season.

Matchup/League Facts

• The Twins rank 28th in the league for runs allowed this season (406).
• The Twins rank 27th in the league for ERA this season (4.79).
• The Dodgers rank 1st in the league for batting average this season (.259).
• The Dodgers rank 1st in the league for on-base percentage this season (.343).

Los Angeles Dodgers vs. Minnesota Twins Prediction

I’m on the Twins in this one. Right now, the Twins are just playing the better baseball and I feel like Zebby Matthews is the better starter in this matchup. I’m still not sold on Eric Lauer, especially being favored at this price, and I think the Twins take down the Dodgers to draw first blood in the series.