Twins vs Yankees Prediction 9/15/25 MLB Picks Today

The New York Yankees and the Minnesota Twins meet Monday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Twins vs Yankees Prediction.

Starting Pitching Matchup

The New York Yankees will send out Carlos Rodon here and Rodon is 16-8 with a 3.11 ERA and 186 strikeouts this season. In his last five starts against the Twins, Rodon is 4-0 with a 2.70 ERA and 37 strikeouts. Simeon Woods Richardson will get the start for the Twins here and is 6-4 with a 4.58 ERA and 84 strikeouts this season. This will be Woods Richardson’s first career start against the Yankees.

New York Yankees Recap

The New York Yankees come into this game looking to rebound from their 6-4 loss at the hands of the Boston Red Sox in Sunday’s series finale to slip to 83-66 this season. After this series, the Yankees will head on the road for a series against the Baltimore Orioles.

Yankees Have Three-Game Win Streak Snapped

Aaron Judge leads the Yankees with 163 hits including 48 home runs, 102 RBIs, 28 doubles and a .326 batting average along with 11 stolen bases. Anthony Volpe’s also had 29 doubles with 16 stolen bases, 19 home runs and 70 RBIs while Jasson Dominguez has added 17 doubles of his own. Paul Goldschmidt has 126 hits with 30 doubles and a .278 batting average while Volpe also has 140 strikeouts so far this season. Ben Rice also has 105 hits with 25 doubles, 23 home runs and 56 RBIs while Cody Bellinger has 28 homers with 93 RBIs and Austin Wells has 21 home runs and 66 RBIs with Bellinger logging 25 doubles and Wells chipping in 19 doubles. Trent Grisham also has 30 home runs and 64 RBIs and Jazz Chisholm Jr. has 29 home runs and 75 RBIs so far this season.

Why the New York Yankees will win

• The Yankees have won each of their last eight night games against teams that held a losing record.
• The Twins have lost each of their last seven home games against American League opponents.
• The Yankees have covered the run line each of their last eight night games against teams that held a losing record.
• The Twins have failed to cover the run line in each of their last seven home games.

New York Yankees Player Prop Facts

• Aaron Judge has hit at least one home run in four of the Yankees’ last five games against AL Central opponents.
• Carlos Rodon has recorded a win in eight of his last nine appearances with his team as a favorite against the Twins .
• Anthony Volpe has recorded at least one hit in each of the Yankees’ last 16 games against the Twins.
• Aaron Judge has recorded two or more Doubles in three of the Yankees’ last four road games against the Twins.
• Jose Caballero ranks 1st in the league in Steals (46) this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to rebound from their 6-4 loss at the hands of the Arizona Diamondbacks last time out to sit at 65-84 this season. After this series, the Twins will welcome the Cleveland Guardians to town for a series.

Twins Drop 4 Of Last 5 In Another Series Loss

Byron Buxton has 119 hits along with 18 doubles, a team-high 31 home runs and 76 RBIs with 22 stolen bases and 7 triples while Trevor Larnach’s chipped in 119 hits with 21 doubles, 16 home runs and 58 RBIs as well this season. Brooks Lee has contributed 105 hits with 14 doubles, 14 home runs and 58 RBIs and Matt Wallner has 22 homers and 40 RBIs as well. 

Why the Minnesota Twins will win

• The underdogs have won six of the Twins’ last seven games at Target Field.
• The Yankees have lost three of their last four games as favorites against AL Central opponents.
• The underdogs have covered the run line in each of the Twins’ last 13 games.
• The Yankees have failed to cover the run line in nine of their last 11 games as favorites against American League opponents following a road loss.

Minnesota Twins Player Prop Facts

• Byron Buxton has hit at least one home run in three of his last four home appearances against the Yankees.
• Trevor Larnach has recorded at least one hit in each of the Twins’ last eight home games against AL opponents.
• Byron Buxton ranks 5th amongst qualified players for Slugging Percentage (.555) this season.

Total Runs Facts

• Six of the Twins’ last seven night games as underdogs have gone OVER the total runs line.
• Five of the Yankees’ last six night games against AL Central opponents have gone OVER the total runs line.

Twins vs Yankees Prediction

I’m on the Yankees here. I still think that Woods Richardson is still the weak link of this Minnesota rotation, and this Yankee lineup is still one of the more potent lineups in all of baseball against right-handed pitching. The Twins have been hit or miss against lefties. While they could have their moments against Rodon who has been less effective on the road this season, I still think he’s good enough here to get the win in this one. I’m on New York here.