Twins vs Yankees Prediction 9/17/25 MLB Picks Today

The New York Yankees and the Minnesota Twins meet Wednesday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Twins vs Yankees Prediction.

Starting Pitching Matchup

The New York Yankees will give the start to Luis Gil here and Gil is 4-1 with a 2.83 ERA and 34 strikeouts this season. In his career, Gil is 1-0 with a 3.75 ERA and 14 strikeouts against Minnesota. The Minnesota Twins will start Taj Bradley here and Bradley is 6-7 with a 4.88 ERA and 114 strikeouts this season. In his career, Bradley is 2-2 with a 3.42 ERA and 16 strikeouts against the Yankees.

New York Yankees Recap

The New York Yankees come into this game looking to add on to their 10-9 win over the Twins from Tuesday’s matchup to improve to 84-67 this season. After this set, the Yankees will go on the road once again for a division series against the Baltimore Orioles.

Yankees Win 4 Of Their Last 6

Aaron Judge leads the Yankees with 163 hits including 48 home runs, 102 RBIs, 28 doubles and a .326 batting average along with 11 stolen bases. Anthony Volpe’s also had 29 doubles with 16 stolen bases, 19 home runs and 70 RBIs while Jasson Dominguez has added 17 doubles of his own. Paul Goldschmidt has 126 hits with 30 doubles and a .278 batting average while Volpe also has 140 strikeouts so far this season. Ben Rice also has 105 hits with 25 doubles, 23 home runs and 56 RBIs while Cody Bellinger has 28 homers with 93 RBIs and Austin Wells has 21 home runs and 66 RBIs with Bellinger logging 25 doubles and Wells chipping in 19 doubles. Trent Grisham also has 30 home runs and 64 RBIs and Jazz Chisholm Jr. has 29 home runs and 75 RBIs so far this season.

Why the New York Yankees will win

• The Yankees have won 20 of their last 21 night games against AL Central opponents following a road win.
• The Twins have lost eight of their last nine home games against American League opponents.
• The Yankees have covered the run line in eight of their last nine games against the Twins following a win.
• The Twins have failed to cover the run line in six of their last seven night games at Target Field following a home loss.

New York Yankees Player Prop Facts

• Anthony Volpe has recorded a Double in each of his three previous appearances with the Yankees as road favorites against the Twins.
• Anthony Volpe has recorded at least one hit in each of his 15 previous appearances against the Twins after playing the previous day.
• Trent Grisham has hit at least one home run in four of the Yankees’ last six night games against AL opponents that held a losing record.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to respond to their narrow loss to New York from Tuesday’s matchup to fall to 66-85 this season. After this series, the Minnesota Twins will square off against the rival Cleveland Guardians in a home division series.

Twins Drop 5 Of Their Last 7

Byron Buxton has 119 hits along with 18 doubles, a team-high 31 home runs and 76 RBIs with 22 stolen bases and 7 triples while Trevor Larnach’s chipped in 119 hits with 21 doubles, 16 home runs and 58 RBIs as well this season. Brooks Lee has contributed 105 hits with 14 doubles, 14 home runs and 58 RBIs and Matt Wallner has 22 homers and 40 RBIs as well. 

Why the Minnesota Twins will win

• The Twins have won four of their last five games as home underdogs against AL East opponents following a loss.
• The Yankees have lost three of their last four games as favorites following a road win.
• The underdogs have covered the run line in each of the Twins’ last 15 games.
• The Yankees have failed to cover the run line in each of their last six Wednesday games as favorites against American League opponents.

Minnesota Twins Player Prop Facts

• Trevor Larnach has recorded a Double in three of the Twins’ last four games as home underdogs against AL opponents.
• Trevor Larnach has recorded at least one hit in each of the Twins’ last 10 home games against AL opponents.
• James Outman has hit a home run in each of his last three appearances with the Twins as underdogs.

Total Runs Facts

• Four of the last five games between the Yankees and Twins at Target Field have gone UNDER the total runs line.
• Four of the Yankees’ last five games against AL Central opponents have gone OVER the total runs line.

Twins vs Yankees Prediction

I’m on the Yankees here. I just think that the Yankees are the more trustworthy and potent offense in this spot. I trust them to get to Taj Bradley a heck of a lot easier than I trust the Twins to get to Luis Gil. Now, Gil has had issues with walks piling up in some of his starts, but I don’t think the Twins are disciplined enough at the plate to draw those walks and create that havoc on the bases. I think the Yankees end up with the W here so give me New York.