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Nationals vs Astros Prediction 7/6/26 MLB Picks Today

Houston Astros (45-47) vs. Washington Nationals (46-45)
July 6, 2026 6:45 pm EDT
The Line: Washington Nationals -120 / Houston Astros -101; Over/Under: 9.5
(Get latest betting odds)

In this article we will formulate a Nationals vs Astros prediction for this MLB game on Monday, July 6th at Nationals Park in Washington, DC. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 46-45 this year after they lost two out of three against the Pirates by scores of 9-5, 1-7, and 5-11. In game three, Washington tied the game at four in the fifth inning, but they allowed seven of the last eight runs for the loss. The Nationals recorded 10 hits and they committed one error in the game, while they were led by Garcia Jr, who went 2-5 with home run and two RBIs. Cavalli allowed six hits and three earned runs over 2.1 innings, while Lord picked up the loss. Prior to that series, Washington won two out of three against the Red Sox and two out of three against the Orioles. 

This season, Washington has a 4.72 ERA with a 1.39 WHIP and a .259 opponent batting average, while they have scored 485 runs with a .249 batting average and a .323 on base percentage. CJ Abrams has led the Nationals with 18 home runs and 61 RBIs, while James Wood has added 23 home runs and 56 RBIs. The projected starting pitcher for Washington is Miles Mikolas, who is 2-7 with a 5.44 ERA and a 1.29 WHIP over 84.1 innings pitched this year. 

Houston Astros Betting Preview

The Houston Astros are 45-47 this season after they won two out of three against the Rays by scores of 1-3, 10-8, and 2-0. In game three, Houston scored once in the fourth inning and once in the sixth inning in the shutout win. The Astros recorded six hits in the game and they were led by Paredes, who went 2-4 with one home run and one RBI. Lambert allowed three hits and zero earned runs over 5.2 innings for the win, while Hader picked up a save. Prior to that series, Houston lost two out of three against the Twins, but did win three out of four against the Tigers before that. 

This season, Houston has a 4.72 ERA with a 1.38 WHIP and a .239 opponent batting average, while they have scored 413 runs with a .241 batting average and a .315 on base percentage. Yordan Alvarez has led the Astros with 29 home runs and 67 RBIs, while Christian Walker has added 20 home runs and 57 RBIs. The projected starting pitcher for Houston is Mike Burrows, who is 4-8 with a 5.58 ERA and a 1.51 WHIP over 90.1 innings pitched this season. 

Why the Washington Nationals will win

  • The Nationals have won each of their last eight games as favorites against the Astros.
  • The Astros have lost each of their last seven Monday games against National League opponents that held a winning record.
  • The Astros have failed to cover the run line in each of their last six road games following a home win.
  • The Nationals have covered the run line in 20 of their last 24 games against American League opponents after playing the previous day.
  • The Nationals have won the first inning in four of their last five night games at Nationals Park.
  • The Nationals have led after 5 innings in six of their last seven home night games.
  • The Nationals have led after 3 innings in each of their last seven home night games.

Why the Houston Astros will win

  • The Astros have won five of their last six games as underdogs.
  • The Nationals have lost each of their last five home games after playing the previous day.
  • The Astros have covered the run line each of their last eight games at Nationals Park against teams that held a winning record.
  • The Nationals have failed to cover the run line in five of their last six games against AL West opponents that held a losing record.
  • The Nationals have trailed after 3 innings in five of their last six games against AL West opponents that held a losing record.
  • The Nationals have lost the first inning in three of their last four games against American League opponents.
  • The Astros have led after 5 innings in each of their last seven night games against NL East opponents.

Total Runs Facts

  • Seven of the Astros’ last eight games against NL East opponents have gone OVER the total runs line.
  • Twelve of the Nationals’ last 14 games as favorites have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of the Astros’ last four road games.
  • There has been at least one run scored in the first inning in each of the Nationals’ last four games against American League opponents.

Washington Nationals Player Prop Facts

  • Luis Garcia has hit at least one home run in five of his last six home appearances.
  • Miles Mikolas has recorded four or more strikeouts in four of his last five appearances with his team as a favorite.
  • Keibert Ruiz has recorded at least one hit in each of his last nine appearances against AL opponents.
  • Miles Mikolas has recorded a win in three of his last four home appearances against AL opponents.
  • Nasim Nunez ranks 1st in the league in Steals (32) this season.

Houston Astros Player Prop Facts

  • Yordan Alvarez has hit at least one home run in three of the Astros’ last four games against opponents that held a winning record.
  • Mike Burrows has recorded five or more strikeouts in three of his four previous appearances against NL East opponents.
  • Isaac Paredes has recorded at least one hit in each of the Astros’ last eight games against opponents that held a winning record.
  • Yordan Alvarez ranks 1st amongst qualified players for Slugging Percentage (.637) this season.

Matchup/League Facts

  • The Nationals rank 1st in the league for runs scored this season (485).
  • The Nationals rank 1st in the league for RBIs this season (461).
  • The Astros rank 30th in the league for steals this season (29).
  • The Astros rank 28th in the league for walks allowed this season (397).

Nationals vs Astros Prediction

Houston comes into this matchup after a great series win over the Rays, but they have scored three runs or fewer in three of their last four games. The Astros are 22-23 on the road this year, while the Nationals are 18-27 at home. Washington has lost two games in a row and they allowed 23 runs in their three games against the Pirates. The Nationals are starting Mikolas, who has allowed 6, 0, and 5 earned runs in his last three outings, while Burrows has allowed 4, 1, 0, 4, and 4 earned runs in his last five outings. Take the over here. 

David Racey's Free Pick: Over 9.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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