
Nationals vs Cubs Prediction 6/4/25 MLB Picks Today
Chicago Cubs (38-22) vs. Washington Nationals (28-32)
June 4, 2025 6:45 pm EDT
The Line: Washington Nationals 120 / Chicago Cubs -142; Over/Under: 8.5
(Get latest betting odds)
The Chicago Cubs and Washington Nationals meet Wednesday in MLB action at Nationals Park. Here’s a Nationals vs Cubs Prediction. This article will include a Nationals vs Cubs Pick.
Chicago Cubs Betting Preview
The Chicago Cubs are 38-22 on the year and play the Tigers, Phillies, and Pirates next. The Chicago Cubs are batting .262 on the season, have a .335 OBP, and a .448 slugging percentage. The Chicago Cubs pitching staff has a 3.83 ERA and a 1.25 WHIP. Nico Hoerner leads the Chicago Cubs with 66 hits and 28 RBI, while Pete Crow-Armstrong and Kyle Tucker have combined for 130 hits and 90 RBI.
Matthew Boyd gets the ball for the Chicago Cubs, and he is 5-2 with a 3.08 ERA and 64 strikeouts this season. This will be Boyd’s second career game against the Washington Nationals.
Washington Nationals Betting Preview
The Washington Nationals are 28-32 on the year and play the Rangers, Mets, and Marlins next. The Washington Nationals are batting .244 on the season, have a .312 OBP, and a .395 slugging percentage. The Washington Nationals’ pitching staff has a 5.07 ERA and a 1.39 WHIP. James Wood leads the Washington Nationals with 65 hits and 45 RBI, while Keibert Ruiz and Nathaniel Lowe have combined for 105 hits and 62 RBI.
MacKenzie Gore gets the ball for the Washington Nationals, and he is 2-5 with a 3.16 ERA and 101 strikeouts this season. Gore is 2-2 with a 5.24 ERA and 25 strikeouts in his career against the Chicago Cubs.
Why the Washington Nationals will win
- The underdogs have won 11 of the Nationals’ last 15 games.
- The Cubs have lost six of their last eight night games against the Nationals at Nationals Park following a road win.
- The Cubs have failed to cover the run line in each of their last nine Wednesday games as favorites.
- The Nationals have covered the run line in nine of their last 10 games as underdogs after playing the previous day.
- The Nationals have led after 3 innings in four of their last five games as home underdogs.
Why the Chicago Cubs will win
- The Nationals have lost each of their last six home games against NL Central opponents that held a winning record.
- The Cubs have won nine of their last 10 games against the Nationals.
- The Nationals have failed to cover the run line in each of their last six home games against NL Central opponents following a loss.
- The Cubs have covered the run line each of their last three games at Nationals Park against teams that held a losing record.
- The Cubs have led after 5 innings in each of their last four games against the Nationals at Nationals Park.
Washington Nationals Player Prop Facts
- Josh Bell has hit a home run in four of his last seven appearances after playing the previous day.
- Amed Rosario has recorded a Double in four of his last five home appearances against opponents that held a winning record.
- Nathaniel Lowe has recorded at least one RBI in four of the Nationals’ last five games.
- Josh Bell has recorded at least one Single in each of the Nationals’ last six games as underdogs.
- CJ Abrams has scored at least one run in each of the Nationals’ last six games as underdogs.
- MacKenzie Gore has recorded seven or more strikeouts in each of his last six appearances at Nationals Park.
- CJ Abrams has recorded at least one hit in each of the Nationals’ last seven games against NL Central opponents.
- James Wood ranks T6th in the league in Home Runs (16) this season.
Chicago Cubs Player Prop Facts
- Seiya Suzuki has recorded a Double in three of the Cubs’ last four road games against NL opponents.
- Carson Kelly has scored at least one run in each of his last six appearances with the Cubs as road favorites.
- Seiya Suzuki has recorded at least one RBI in each of the Cubs’ last five night games against NL teams that held a losing record.
- Matthew Boyd has recorded six or more strikeouts in five of his last six appearances.
- Carson Kelly has recorded at least one Single in each of his 10 previous appearances with the Cubs as road favorites.
- Carson Kelly has recorded at least one hit in each of his last 10 appearances with his team as a road favorite against NL opponents.
- Kyle Tucker has hit a home run in each of his last two road appearances against NL East opponents.
- Pete Crow-Armstrong ranks 8th amongst qualified players for Slugging Percentage (.562) this season.
Nationals vs Cubs Prediction
You can make a case for the Nationals and the plus money with Gore on the mound, as he has a 3.16 ERA and leads baseball in strikeouts. The problem is the Nationals aren’t winning enough games to take them seriously. The Cubs are the more trustworthy offense; they’ve been on a tear over the last month, and Boyd looks like he could be an all-star for the first time with his 3.08 ERA and 1.26 WHIP. I’ll take the Cubs and the soft price.