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Nationals vs Marlins Prediction 8/22/26 MLB Picks Today

Washington Nationals (61-69) vs. Miami Marlins (65-64)
August 22, 2026 4:10 pm EDT
The Line: Miami Marlins -175 / Washington Nationals 163; Over/Under: 7.5
(Get latest betting odds)

In this article, we will formulate a Nationals vs Marlins Prediction for this MLB matchup on Saturday, August 22nd in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Preview

The Miami Marlins have a 65-64 record this season and are sitting in the 3rd place of the NL East. They have a 39-25 home record and are coming off a 3-2 home win against the Nationals. They will face the Red Sox and the Nationals next.

The Miami Marlins have a .249 batting average this season, .326 OBP and .401 Slugging percentage. Miami’s pitching staff has a 3.94 ERA and 1.25 WHIP. Otto Lopez is the Marlins’ best hitter with a .307 batting average, while also leading the team in RBI with 55. Heriberto Hernandez adds a team-high 18 home runs.

Eury Perez (R) is the projected starting pitcher for the Marlins, and he has a 6-9 record, 3.23 ERA and 1.11 WHIP.

Washington Nationals Preview

The Washington Nationals have a 61-69 record this season and are sitting in the 4th place of the NL East. They have a 34-33 road record and are coming off a 2-3 road loss against the Marlins. They will face the Rockies and the Marlins next.

The Washington Nationals have a .249 batting average this season, .325 OBP and .433 Slugging percentage. Washington’s pitching staff has a 4.67 ERA and 1.39 WHIP. CJ Abrams is the Nationals’ best hitter with a .279 batting average, while also leading the team in RBI with 91. James Wood adds a team-high 30 home runs.

Jake Irvin (R) is the projected starting pitcher for the Nationals, and he has a 2-7 record, 5.80 ERA and 1.36 WHIP.

Washington Nationals @ Miami Marlins Betting Trends: August 22, 2026

 

  • Probable Starting Pitcher: Eury Perez      Record this season: 6-9      ERA: 3.23
  • Home Record: 4-4
  • Last 5 against Nationals: 0-1

Why the Miami Marlins will win

  • The Marlins have won each of their last 10 games as favorites against NL East opponents.
  • The Nationals have lost 14 of their last 15 games against NL East opponents.
  • The Marlins have covered the run line in 16 of their last 17 day games following a win.
  • The Nationals have failed to cover the run line in 10 of their last 11 day games against the Marlins following a loss.
  • The Nationals have trailed after 3 innings in six of their last seven road games against opponents that held a winning record.
  • The Nationals have trailed after 5 innings in six of their last seven road games against opponents that held a winning record.

 

  • Probable Starting Pitcher: Jake Irvin      Record this season: 2-7      ERA: 5.80
  • Road Record: 2-3
  • Last 5 against Marlins: 1-1

Why the Washington Nationals will win

  • The Marlins have lost six of their last seven games against NL East opponents.
  • The Nationals have won eight of their last 10 day games against National League opponents that held a winning record.
  • The Nationals have covered the run line in 17 of their last 18 Saturday day games as road underdogs against National League opponents.
  • The Marlins have failed to cover the run line in six of their last seven games against NL East opponents.
  • The Nationals have led after 5 innings in eight of their last 10 day games against opponents that held a winning record.

Total Runs Facts

  • Each of the Marlins’ last seven games as favorites against NL East opponents have gone UNDER the total runs line.
  • Seven of the Nationals’ last eight games have gone UNDER the total runs line.
  • There has been no run scored during the first inning in each of Eury Perez’s last seven appearances as a starter.
  • There has been no run scored during the first inning in seven of the Nationals’ last eight day games against NL East opponents.

Miami Marlins Player Prop Facts

  • Heriberto Hernandez has hit a home run in three of the Marlins’ last five home games against NL East opponents.
  • Eury Perez has recorded a win in three of his last four appearances with the Marlins as home favorites against NL opponents.
  • Javier Sanoja has recorded at least one hit in each of the Marlins’ last seven games against NL East opponents.
  • Otto Lopez ranks 2nd in the league in Hits (154) this season.

Washington Nationals Player Prop Facts

  • Abimelec Ortiz has hit a home run in three of the Nationals’ last four day games.
  • Jake Irvin has recorded five or more strikeouts in seven of his last nine appearances in day games.
  • Daylen Lile has recorded at least one hit in each of the Nationals’ last eight road games against the Marlins.
  • Nasim Nunez ranks 1st in the league in Steals (42) this season.

Matchup/League Facts

  • The Marlins rank 2nd in the league for triples this season (28).
  • The Marlins rank 2nd in the league for steals this season (131).
  • The Nationals rank 1st in the league for runs scored this season (678).
  • The Nationals rank 1st in the league for home runs this season (183).

Nationals vs Marlins Prediction

The Astros are 3-1 in their last 4 meetings against the Athletics and are 3-1 in their last 4 meetings in Houston.

In this Nationals vs Marlins Prediction, the Marlins are coming as -175 home favorites. I like the Marlins in this one, as they will be facing a struggling Nationals team that is just 2-8 in its last 10 games and has an ice-cold offense, averaging just 2.2 runs per game in their last 5. Things won’t get any easier with Jake Irvin on the mound, who has given up 4+ runs in three of his last four starts, while the Marlins will start Eury Perez who has back-to-back shutouts and has been better at home with a 2.90 ERA. Take the Marlins in this one.

Nikos Lagouretos's Free Pick: Miami Marlins ML

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