
Nationals vs Padres Prediction 7-18-25 MLB Picks
San Diego Padres (52-44) vs. Washington Nationals (38-58)
July 18, 2025 6:45 pm EDT
The Line: Washington Nationals 128 / San Diego Padres -157; Over/Under: 8.5
(Get latest betting odds)
The San Diego Padres and Washington Nationals meet Friday in MLB action at Nationals Park. Here’s a Nationals vs Padres Prediction. This article will include a Nationals vs Padres Pick.
San Diego Padres Betting Preview
The San Diego Padres are 52-44 on the year and play the Marlins, Cardinals, and Mets next. The San Diego Padres are batting .246 on the season, have a .315 OBP, and a .374 slugging percentage. The San Diego Padres pitching staff has a 3.64 ERA and a 1.24 WHIP. Manny Machado leads the San Diego Padres with 107 hits and 56 RBI, while Luis Arraez and Fernando Tatis Jr. have combined for 198 hits and 77 RBI.
Dylan Cease gets the ball for the San Diego Padres, and he is 3-9 with a 4.88 ERA and 129 strikeouts this season. Cease is 2-0 with a 0.00 ERA and 18 strikeouts in his career against the Washington Nationals.
Washington Nationals Betting Preview
The Washington Nationals are 38-58 on the year and play the Reds, Twins, and Astros next. The Washington Nationals are batting .245 on the season, have a .311 OBP, and a .389 slugging percentage. The Washington Nationals pitching staff has a 5.21 ERA and a 1.41 WHIP. James Wood leads the Washington Nationals with 99 hits and 69 RBI while CJ Abrams and Nathaniel Lowe have combined for 177 hits and 94 RBI.
Michael Soroka gets the ball for the Washington Nationals, and he is 3-7 with a 5.35 ERA and 74 strikeouts this season. Soroka is 2-0 with a 0.60 ERA and 20 strikeouts in his career against the San Diego Padres.
Why the Washington Nationals will win
- The Padres have lost five of their last six games as road favorites.
- The Nationals have won four of their last five games as underdogs against NL West opponents following a loss.
- The Nationals have covered the run line in each of their last seven games as home underdogs against NL West opponents.
- The Padres have failed to cover the run line in eight of their last nine games as favorites against National League opponents.
- The Nationals have won the first inning in three of their last four night games at Nationals Park.
- The Nationals have led after 5 innings in six of their last seven games as home underdogs against NL West opponents.
- The Nationals have led after 3 innings in seven of their last eight games as home underdogs against NL West opponents.
Why the San Diego Padres will win
- The Padres have won each of their last eight games as favorites following a loss.
- The Nationals have lost eight of their last nine games.
- The Nationals have failed to cover the run line in each of their last eight home games against National League opponents.
- The Padres have covered the run line in each of their last seven road games against NL East opponents following a home loss.
- The Nationals have trailed after 3 innings in seven of their last eight games as home underdogs.
- The Nationals have trailed after 5 innings in eight of their last nine games.
Washington Nationals Player Prop Facts
- CJ Abrams has hit a home run in four of the Nationals’ last five Friday games against NL West opponents that held a winning record.
- Michael Soroka has recorded five or more strikeouts in six of his last seven appearances.
- CJ Abrams has recorded at least one hit in each of the Nationals’ last 12 night games.
- Amed Rosario has recorded a Double in three of the Nationals’ last four games as home underdogs against NL West opponents.
- James Wood ranks T8th in the league in Home Runs (24) this season.
San Diego Padres Player Prop Facts
- Luis Arraez has hit a home run in each of his two previous road appearances against the Nationals after not playing the previous day.
- Dylan Cease has recorded six or more strikeouts in eight of his last nine appearances in night games.
- Jose Iglesias has recorded at least one hit in each of his last 14 road appearances against NL East opponents.
- Manny Machado has recorded at least one Double in three of his last four appearances against the Nationals after not playing the previous day.
- Manny Machado ranks 6th in the league in Hits (107) this season.
Nationals vs Padres Prediction
I expect some fireworks in this spot, so I’m taking the over. Cease has allowed 18 hits and 13 earned runs in his last 16 innings. In 51.2 road innings, Cease has a 6.27 ERA and .270 allowed batting average. Soroka has a 5.35 ERA on the season, and he’s allowed 13 hits and nine runs in his last eight innings. In 27 home innings, Soroka has a 5.67 ERA and .250 allowed batting average. Two struggling pitchers and fresh legs at the plate. We should see some runs, folks. Give me the over.