Nationals vs Reds Prediction 7/21/25 MLB Picks Today

In this article, we will formulate a Nationals vs Reds prediction for this MLB game on Monday, July 21st at Nationals Park in Washington, DC. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview

The Washington Nationals are 39-60 this season after they lost two out of three against San Diego by scores of 2-7, 4-2, and 1-8. In their game three loss, Washington cut the deficit to 8-1 in the fifth inning, but couldn’t find any more offense in the blowout loss. The Nationals recorded six hits in the game, and they were led by Adams, who went 1-3 with one home run and one RBI in the loss. Washington started Gore, who allowed eight hits and eight earned runs over 2.1 innings for the loss, while Rutledge allowed two hits and zero earned runs over 3.2 innings in relief. 

Prior to that series, the Nationals lost all three against the Brewers and two out of three against the Cardinals. Washington has lost 10 of their last 12 games, and they are currently last in the NL East standings. The Washington pitching staff has a 5.22 ERA with a 1.41 WHIP and a .264 opponent batting average, while the offense has scored 424 runs with a .244 batting average and a .310 on-base percentage this season. James Wood has led Washington with 24 home runs and 69 RBIs, while Nathaniel Lowe has added 15 home runs and 62 RBIs this year. The projected starting pitcher for Washington is Jake Irvin, who is 7-5 with a 4.58 ERA and a 1.29 WHIP over 116.0 innings pitched this season. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 52-48 this year after they won two out of three against the Mets by scores of 8-4, 5-2, and 2-3. In their game three loss, Cincinnati tied the game at two in the top of the eighth, but they allowed a run in the bottom of the inning for the loss. The Reds recorded seven hits in the game, and they were led by De La Cruz and Steer, who both had one RBI in the loss. Cincinnati started Abbott, who allowed six hits and two earned runs over 6.0 innings, while Suter picked up the loss in relief. 

Prior to that series, the Reds won two out of three against the Rockies and split four games with the Marlins. Cincinnati has won four of its last five games, and they are currently third in the NL Central standings. The Cincinnati pitching staff has a 3.87 ERA with a 1.24 WHIP and a .235 opponent batting average, while their offense has scored 456 runs with a .246 batting average and a .318 on-base percentage this season. Elly De La Cruz has led Cincinnati with 18 home runs and 65 RBIs, while Spencer Steer has added 11 home runs and 40 RBIs this year. The projected starting pitcher for Cincinnati is Brady Singer, who is 7-7 with a 4.32 ERA and a 1.35 WHIP over 100.0 innings pitched this year. 

Why the Nationals will beat the Reds

• The Nationals have won each of their last three games as underdogs against the Reds following a loss.
• The Reds have lost four of their last five games as favorites following a road loss.
• The Nationals have covered the run line in seven of their last eight games against the Reds.
• The Reds have failed to cover the run line in eight of their last nine games against the Nationals following a loss.
• The Reds have trailed after 3 innings in each of their last five road night games.
• The Nationals have led after 5 innings in each of their last six Monday night games against National League opponents that held a winning record.
• The Reds have lost the first inning in three of their last four road games against opponents that held a losing record.

Why the Reds will beat the Nationals

• The Nationals have lost eight of their last nine home games against NL Central opponents.
• The Reds have won four of their last five games.
• The Nationals have failed to cover the run line in 10 of their last 11 home games against National League opponents.
• The Reds have covered the run line in each of their last five games against NL East opponents.
• The Reds have led after 3 innings in each of their last seven night games against the Nationals.
• The Nationals have trailed after 5 innings in eight of their last nine home games against NL Central opponents.
• The Reds have won the first inning in five of their last six games as favorites against National League opponents.

Total Runs Facts

• Each of the Reds’ last six games after playing the previous day have gone UNDER the total runs line.
• Eight of the Nationals’ last nine home games have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Reds’ last six games against NL East opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 11 of the last 13 night games between the Reds and Nationals.

Washington Nationals Player Prop Facts

• Amed Rosario has hit a home run in three of his last five appearances in night games against NL Central teams that held a winning record.
• CJ Abrams has recorded at least one hit in each of the Nationals’ last 14 night games.
• Josh Bell has recorded a Double in four of the Nationals’ last five night games against NL Central opponents that held a winning record.

Cincinnati Reds Player Prop Facts

• Brady Singer has recorded a win in three of his last four appearances with his team as a road favorite.
• Elly De La Cruz has hit a home run in six of the Reds’ last 19 road games.
• Connor Joe has recorded at least one hit in each of his last 10 road appearances against NL East opponents that held a losing record.
• Elly De La Cruz has recorded at least one Double in four of the Reds’ last five games at Nationals Park against opponents that held a losing record.

Matchup/League Facts

• The Nationals rank 28th in the league for ERA this season (5.22).
• The Nationals rank 28th in the league for opponent batting average this season (.264).
• The Reds rank 6th in the league for opponent batting average this season (.235).
• The Reds rank T7th in the league for hits allowed this season (782).

Nationals vs Reds Prediction 

Washington limps into this matchup, really struggling over the last few weeks, and they have one of the worst records in all of baseball. The Nationals are 19-30 at home this year, while the Reds are 24-26 on the road. Cincinnati is playing some solid ball right now, and they are starting Singer, who has allowed two earned runs or fewer in three of his last five starts. The Nats are going with Irvin, who has allowed 0, 4, 3, and 8 earned runs in his last four. This Washington pitching staff has been a disaster, and they have gone over 8.5 runs in seven of their last eight games. Take the over here.