Chicago White Sox (59-101) vs. Washington Nationals (65-95)
September 27, 2025 4:05 pm EDT
The Line: Washington Nationals -121 / Chicago White Sox -101; Over/Under: 8.5
(Get latest betting odds)
The Washington Nationals and Chicago White Sox meet on Saturday in MLB action from Nationals Park. Here’s a Nationals vs White Sox prediction. We will look at this from a betting perspective and determine the best Nationals vs White Sox pick.
White Sox Pulled it Out
It wasn’t the prettiest game, but the White Sox were able to pull out the victory with two runs in the 9th inning. It was mostly a balanced offensive attack but Colson Montgomery and Lenyn Sonsa both hit home runs. The White Sox did use four bullpen members and they might be a little shorthanded on the back end here.
The White Sox are averaging 3.93 runs while their pitching is giving up 4.57 runs per game. The offense is ranked 28th while the pitching is ranked 21st. This is an offense that hasn’t scored enough runs, and the pitching hasn’t been dominant to make up for the lack of scoring. Lenyn Sosa has been a bright spot for the offense hitting 22 home runs and driving in 75 RBIs so far this season. Sean Burke gets the start for the White Sox and sits with a 4-11 record and an ERA of 4.29. In his last start against the San Diego Padres he went four innings giving up six hits and three runs.
National Fell Just Short
The Nationals scored four runs in the 8th inning to take the lead, but the pitching then gave up two in the top of the 9th and that led to the defeat. Luis Garcia Jr had qute the game hitting three home runs and driving in four RBIs. Orlando Ribalta was a problem out of the bullpen and he went 0.1 innings giving up two this and two runs.
The Nationals are averaging 4.23 runs while their pitching is giving up 5.51 runs per game. The offense is ranked 20th while the pitching is ranked 29th. James Wood has hit 30 home runs and driven in 92 RBIs. Getting the start for the Nationals will be Jake Irvin who went four innings in his last start giving up six hits and three runs. He overall sits with a 9-13 record and an ERA of 5.69.
Nationals vs White Sox Prediction
There was no shortage of scoring on Friday night, and it’s going to be much of the same here for both teams. Irvin sits with an ERA of 5.69 and he’s going to have some major issues in this game. The White Sox offense has confidence, and they are going to build off of that here. For the White Sox they send Burke who had some struggles in his last start and he’s going to be lit up in this game in a big way. Both teams are scoring at least five runs here, and the over is going to end up cashing.
