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New York Yankees vs Chicago White Sox 5/21/22 MLB Picks, Predictions, Odds

Chicago White Sox (19-19) vs. New York Yankees (28-10)
May 21, 2022 1:05 pm EDT
The Line: New York Yankees -222 / Chicago White Sox +190; Over/Under: +8
(Get latest betting odds)

The Chicago White Sox and New York Yankees meet Saturday in MLB action at Yankee Stadium. The Chicago White Sox look for a win after splitting their last 12 games. The New York Yankees look for a win after winning 10 of their last 13 games.

The Chicago White Sox have scored 10 runs in their last three games and three or fewer runs in five of their last seven games. The White Sox have won six of their last nine games when scoring three or fewer runs. Tim Anderson leads the White Sox with 47 hits and 15 RBI, while Luis Robert and Jose Abreu have combined for 65 hits and 31 RBI. Dallas Keuchel gets the ball, and he is 2-3 with a 5.54 ERA and 16 strikeouts this season. Keuchel is 4-4 with a 2.06 ERA and 64 strikeouts in his career against the Yankees.


The New York Yankees have scored 14 runs in their last three games and four or more runs in eight of their last 10 games. The Yankees have won 10 of their last 11 games when scoring four or more runs. Aaron Judge leads the Yankees with 42 hits and 30 RBI, while Giancarlo Stanton and DJ LeMahieu have combined for 75 hits and 48 RBI. Nestor Cortes gets the ball, and he is 2-1 with a 1.35 ERA and 49 strikeouts this season. Cortes is 3-0 with a 1.89 ERA and 21 strikeouts in his career against the White Sox.

The White Sox are 8-2 in their last 10 road games and 6-1 in their last 7 Saturday games. The Yankees are 37-16 in their last 53 home games and 37-14 in their last 51 overall. The under is 6-1 in White Sox last 7 overall. The over is 7-3 in Yankees last 10 overall. The White Sox are 16-37 in the last 53 meetings in New York and 2-10 in the last 12 meetings.

Dallas Keuchel has been better this month, but he still has a 5.54 ERA on the season and has had a control issue. Nestor Cortes has been one of the better pitchers in the league, posting a 1.35 ERA and 49 strikeouts in 40 innings. The New York Yankees offense has also been on fire as of late as the wins continue to pile up. Hard not to side with the Yanks, and I’ll lay the RL for max betting value.

Randy Chambers's Free Pick: New York Yankees -1.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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