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Orioles vs Astros Prediction 8/23/25 MLB Picks Today

Houston Astros (71-58) vs. Baltimore Orioles (59-69)
August 23, 2025 7:05 pm EDT
The Line: Baltimore Orioles -132 / Houston Astros 109; Over/Under: 8.5
(Get latest betting odds)

In this article we will formulate an Orioles vs Astros prediction for this MLB game on Saturday, August 23rd at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 59-69 this season after they lost the first two games in this series by scores of 2-7 and 7-10. In their game three loss, Baltimore fought back to cut the deficit to 7-6 in the seventh inning, but allowed three more in the eighth to seal the loss. The Orioles recorded 13 hits and they committed two errors in the game, while they were led by Jackson, who went 2-5 with three RBIs in the loss. Baltimore started Povich, who allowed four hits and four earned runs over 4.2 innings for the loss, while Bowman allowed two earned runs in relief. 


Prior to this series, the Orioles won both games against the Red Sox and two out of three against the Astros. Baltimore has won three of their last five games and they are currently last in the AL East standings. The Baltimore pitching staff has a 4.69 ERA with a 1.38 WHIP and a .261 opponent batting average, while their offense has scored 556 runs with a .241 batting average and a .307 on base percentage this season. Jackson Holliday has led Baltimore with 15 home runs and 49 RBIs, while Gunnar Henderson has added 15 home runs and 57 RBIs this year. The projected starting pitcher for Baltimore is Dean Kremer, who is 9-9 with a 3.97 ERA and a 1.21 WHIP over 147.1 innings pitched this season. 

Houston Astros Betting Preview

The Houston Astros are 71-58 this year after they won game two in this series by a score of 10-7 on Friday. Houston led 7-3 in the fifth inning, but they needed three insurance runs in the eighth to lock up the victory. The Astros recorded 10 hits in the game and they were led by Pena, who went 2-5 with one home run and four RBIs in the win. Houston started McCullers Jr., who allowed five hits and three earned runs over 4.0 innings, while Okert picked up the win and Abreu got the save. 

Prior to this series, the Astros lost all three against the Tigers and two out of three against the Orioles. Houston has lost four of their last six games and they are currently first in the AL West standings. The Houston pitching staff has a 3.90 ERA with a 1.23 WHIP and a .234 opponent batting average, while their offense has scored 549 runs with a .253 batting average and a .318 on base percentage this season. Jose Altuve has led Houston with 22 home runs and 64 RBIs, while Yanier Diaz has added 18 home runs and 55 RBIs this year. The projected starting pitcher for Houston is Cristian Javier, who is 1-1 with a 3.38 ERA and a 1.00 WHIP over 8.0 innings pitched this year. 

Why the Orioles will beat the Astros

  • The Astros have lost 10 of their last 12 games against American League opponents following a win.
  • The Orioles have won six of their last eight games after playing the previous day.
  • The Astros have failed to cover the run line in 17 of their last 19 games against American League opponents that held a losing record.
  • The Orioles have covered the run line in seven of their last eight games after playing the previous day.
  • The Orioles have led after 5 innings in six of their last eight games as favorites against American League opponents.

Total Runs Facts

  • Each of the Orioles’ last four games against AL West opponents have gone OVER the total runs line.
  • Six of the Astros’ last seven games have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last 11 Saturday night games against AL East opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Orioles’ last nine games.

Baltimore Orioles Player Prop Facts

  • Dean Kremer has recorded five or more strikeouts in each of his last seven appearances against opponents that held a winning record.
  • Gunnar Henderson has recorded at least one hit in each of the Orioles’ last 11 home games.
  • Dean Kremer has recorded a win in four of his five previous appearances against the Astros.
  • Tyler O’Neill has hit a home run in four of his last five appearances with the Orioles as favorites.

Houston Astros Player Prop Facts

  • Christian Walker has hit a home run in each of the Astros’ last three road games against opponents that held a losing record.
  • Cristian Javier has recorded five or more strikeouts in 11 of his last 13 appearances in night games against AL teams that held a losing record.
  • Jake Meyers has recorded at least one hit in each of his last 16 road appearances against AL opponents.
  • Cristian Javier has recorded a win in four of his last five appearances with the Astros as road underdogs against AL East opponents.
  • Christian Walker has recorded at least one Double in three of the Astros’ last four games as underdogs against AL East opponents.

Orioles vs Astros Prediction 

Houston has snapped out of their offensive funk with back to back wins and they have scored 17 runs in those two games. The Astros are 33-31 on the road this season, while the O’s are 30-32 at home. Baltimore has been way too inconsistent and they are starting Kremer, who has allowed one earned run in his last 15.0 innings. Houston is going with Javier, who has allowed three earned runs and six hits over 8.0 innings in two starts this season. I still don’t trust Javier after missing nearly the entire season and Kremer has been solid, so give me the Orioles to win. 

David Racey's Free Pick: Orioles ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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