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Orioles vs Blue Jays Prediction 5/28/26 MLB Picks Today

Toronto Blue Jays (27-29) vs. Baltimore Orioles (26-30)
May 28, 2026 6:35 pm EDT
The Line: Baltimore Orioles -131 / Toronto Blue Jays 109; Over/Under: 8.5
(Get latest betting odds)

In this article we will formulate an Orioles vs Blue Jays prediction for this MLB game on Thursday, May 28th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 26-30 this year after they swept the Rays in three games by scores of 9-7, 6-1, and 11-2. In game three, Baltimore scored the first eight runs in the game and they picked up the very easy win. The Orioles recorded 16 hits in the game and they were led by Alexander, who went 3-4 with one home run and six RBIs. Gibson allowed six hits and one earned run over 5.2 innings for the win, while Cano allowed one earned run in relief. Prior to that series, Baltimore won two out of three against the Tigers, but lost all three against the Rays before that. 

This season, Baltimore has a 4.68 ERA with a 1.43 WHIP and a .261 opponent batting average, while they have scored 254 runs with a .237 batting average and a .317 on base percentage. Pete Alonso has led the Orioles with 10 home runs and 33 RBIs, while Gunnar Henderson has added 13 home runs and 29 RBIs. The projected starting pitcher for Baltimore is Chris Bassitt, who is 4-3 with a 5.51 ERA and a 1.67 WHIP over 47.1 innings pitched this year. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 27-29 this season after they won two out of three against the Marlins by scores of 2-8, 8-1, and 2-1. In game three, Toronto tied the game at one in the fifth inning and they scored the winning run in the sixth. The Blue Jays recorded five hits in the game and they were led by Okamoto, who went 1-2 with one home run and one RBI. Gausman allowed six hits and one earned run over 5.0 innings, while Hoffman picked up the win and Rogers got the save. Prior to that series, Toronto won two out of three against the Pirates and split four games with the Yankees. 

This season, Toronto has a 3.78 ERA with a 1.26 WHIP and a .242 opponent batting average, while they have scored 226 runs with a .243 batting average and a .309 on base percentage. Kazuma Okamoto has led the Blue Jays with 11 home runs and 29 RBIs, while Andres Gimenez has added five home runs and 27 RBIs. The projected starting pitcher for Toronto is Patrick Corbin, who is 2-1 with a 3.86 ERA and a 1.40 WHIP over 44.1 innings pitched this season. 

Why the Baltimore Orioles will win

  • The home team has won eight of the Orioles’ last nine games.
  • The Blue Jays have lost seven of their last eight road games against the Orioles following a win.
  • The Orioles have covered the run line in each of their last seven Thursday games against the Blue Jays.
  • The Blue Jays have failed to cover the run line in each of their last four games as underdogs against the Orioles following a win.
  • The Blue Jays have trailed after 5 innings in four of their last five games at Oriole Park at Camden Yards.
  • The Orioles have won the first inning in five of their last six games as favorites against the Blue Jays at Oriole Park at Camden Yards.
  • The Blue Jays have trailed after 3 innings in four of their last five games at Oriole Park at Camden Yards.

Why the Toronto Blue Jays will win

  • The Blue Jays have won each of their last eight Thursday night games as underdogs against American League opponents.
  • The Orioles have lost seven of their last eight games as favorites against AL East opponents following a home win.
  • The Blue Jays have covered the run line in each of their last eight games against American League opponents after playing the previous day.
  • The Orioles have failed to cover the run line in each of their last seven games as home favorites after playing the previous day.
  • The Blue Jays have led after 3 innings in four of their last five games against AL East opponents that held a losing record.
  • The Orioles have trailed after 5 innings in five of their last six games against opponents that held a losing record.
  • The Orioles have lost the first inning in four of their last five night games at Oriole Park at Camden Yards.

Total Runs Facts

  • Each of the Blue Jays’ last five games as underdogs against the Orioles have gone OVER the total runs line.
  • Six of the last seven games between the Blue Jays and Orioles at Oriole Park at Camden Yards have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Orioles’ last seven night games against American League opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Blue Jays’ last seven games.

Baltimore Orioles Player Prop Facts

  • Chris Bassitt has recorded five or more strikeouts in 17 of his last 18 home appearances against AL East opponents.
  • Leody Taveras has recorded two hits in four of his last five appearances after playing the previous day.
  • Chris Bassitt has recorded a win in each of his last four appearances against AL opponents.
  • Jordan Westburg has hit a home run in two of his last three appearances.

Toronto Blue Jays Player Prop Facts

  • Patrick Corbin has recorded five or more strikeouts in each of his last four road appearances against AL East opponents that held a losing record.
  • Daulton Varsho has recorded at least one hit in each of the Blue Jays’ last seven games as road underdogs.
  • Alejandro Kirk has hit at least one home run in three of his last four appearances against AL opponents that held a losing record.

Orioles vs Blue Jays Prediction 

Baltimore comes into this matchup after a very impressive sweep of the Rays and they have won five of their last six games. The Orioles are 17-13 at home this year, while the Blue Jays are 10-16 on the road. Toronto has split their last four games and they have allowed two total runs in their last two. The Blue Jays are starting Corbin, who has allowed 1, 3, 3, 2, and 2 earned runs in his last five outings, while Bassitt has allowed 3+ earned runs in three of his last four starts. Baltimore is heating up, but I don’t love Bassitt on the mound. Take the Blue Jays on the road. 

David Racey's Free Pick: Blue Jays ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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