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Orioles vs Rays Prediction 6/28/25 MLB Picks Today

Tampa Bay Rays (46-36) vs. Baltimore Orioles (35-46)
June 28, 2025 4:05 pm EDT
The Line: Baltimore Orioles -113 / Tampa Bay Rays -107; Over/Under: 9.5
(Get latest betting odds)

In this article, we will formulate an Orioles vs Rays prediction for this MLB game on Saturday, June 28th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 35-46 this year after they won game one by a score of 22-8 on Friday night. Baltimore trailed 6-0 in the second inning and 7-5 in the fourth, but they erupted for 17 of the last 18 runs in the game for the blowout win. The Orioles recorded 21 hits in the game, and they were led by Sanchez and Mayo, who both had four RBIs in the win. Baltimore started Sugano, who allowed nine hits and seven earned runs over 5.0 innings for the win, while Dominguez picked up a hold. 

Prior to this series, the Orioles lost two out of three against the Rangers and two out of three against the Yankees. Baltimore has lost four of their last six games, and they are currently last in the AL East standings. The Baltimore pitching staff has a 4.92 ERA with a 1.42 WHIP and a .270 opponent batting average, while their offense has scored 337 runs with a .240 batting average and a .307 on-base percentage this season. Cedric Mullins has led Baltimore with 12 home runs and 38 RBIs, while Ryan O’Hearn has added 11 home runs and 30 RBIs this year. The projected starting pitcher for Baltimore is Zach Eflin, who is 6-4 with a 5.46 ERA and a 1.38 WHIP over 61.0 innings pitched this year. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 46-36 this season after they were blown out in game one of this series. Tampa Bay jumped out to a huge lead in the first two innings, but they couldn’t stop Baltimore from scoring runs in the bad loss. The Rays recorded 13 hits and they committed two errors in the game, while they were led by Lowe, who went 3-5 with one home run and four RBIs in the loss. TB started Pepiot, who allowed five hits and four earned runs over 1.2 innings, while Orze picked up the loss in relief. 

Prior to this series, the Rays won all three against the Royals and two out of three against the Tigers. Tampa Bay has won five of its last seven games, and they are currently second in the AL East standings. The Tampa Bay pitching staff has a 3.70 ERA with a 1.19 WHIP and a .236 opponent batting average, while the offense has scored 391 runs with a .258 batting average and a .323 on-base percentage this season. Junior Caminero has led Tampa Bay with 20 home runs and 51 RBIs, while Brandon Lowe has added 17 home runs and 47 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Zack Littell, who is 6-7 with a 3.78 ERA and a 1.10 WHIP over 97.2 innings pitched this season. 

Why the Orioles will beat the Rays

  • The Orioles have won each of their last five day games at Oriole Park at Camden Yards following a win.
  • The Rays have lost each of their last three road games against AL East opponents.
  • The Rays have failed to cover the run line each of their last six games at Oriole Park at Camden Yards against teams that held a losing record.
  • The Orioles have covered the run line in four of their last five games as favorites against the Rays following a win.
  • The Rays have lost the first inning in four of their last five games as road underdogs against American League opponents.
  • The Rays have trailed after 3 innings in four of their last five games as underdogs against American League opponents.
  • The Orioles have led after 5 innings in each of their last four games as favorites against AL East opponents.

Why the Rays will beat the Orioles

  • The Rays have won 10 of their last 11 games as underdogs against AL East opponents following a road loss.
  • The Orioles have lost each of their last six games against AL East opponents following a home win.
  • The Rays have covered the run line in each of their last 11 games against AL East opponents following a road loss.
  • The Orioles have failed to cover the run line in each of their last six games against AL East opponents following a home win.
  • The Orioles have lost the first inning in three of their last four games as home favorites against AL East opponents.
  • The Orioles have trailed after 3 innings in each of their last eight Saturday day games against opponents that held a winning record.
  • The Orioles have trailed after 5 innings in each of their last seven Saturday day games against opponents that held a winning record.

Total Runs Facts

  • Each of the Rays’ last five games as underdogs against American League opponents have gone UNDER the total runs line.
  • Six of the Orioles’ last seven games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Rays’ last seven road games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Orioles’ last five games as home favorites against AL East opponents.

Baltimore Orioles Player Prop Facts

  • Gary Sanchez has hit a home run in three of the Orioles’ last four games as home favorites.
  • Zach Eflin has recorded four or more strikeouts in each of his last nine home appearances against AL East opponents.
  • Gary Sanchez has recorded at least one hit in each of his last 12 appearances with his team as a favorite against AL opponents.
  • Zach Eflin has recorded a win in three of his last four appearances with the Orioles as favorites against AL opponents.
  • Ryan Mountcastle has recorded at least one Double in three of his last four appearances against opponents that held a winning record.

Tampa Bay Rays Player Prop Facts

  • Brandon Lowe has hit a home run in each of his last three appearances in day games against AL teams that held a losing record.
  • Ha-Seong Kim has recorded at least one hit in each of his eight previous appearances with his team as a road underdog against AL East opponents.

Orioles vs Rays Prediction 

Baltimore was able to erupt for 22 runs to start this series, and they should have plenty of momentum coming into this game. The Orioles are 18-21 at home this year, while the Rays are 19-13 on the road. Tampa Bay has been one of the top teams in the MLB over the last few weeks, and they are starting Littell, who has allowed one earned run in two of his last four starts. The O’s are starting Eflin, who has allowed 13 earned runs and 22 hits in his last two starts. Take the over once again here. 

David Racey's Free Pick: Over 9.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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