Orioles vs Yankees Prediction 9/25/26 MLB Picks Today

In this article, we will formulate an Orioles vs Yankees Prediction for this MLB matchup on Friday, September 25^th in today’s double-header. Let’s take a look at the prediction for this MLB matchup.

New York Yankees Preview

The New York Yankees have a 92-67 record this season and are sitting in the 2nd place of the AL East. They have a 45-33 home record and are coming off a 6-4 home win against the Rays.

The New York Yankees have a .234 batting average this season, .311 OBP and .410 Slugging percentage. New York’s pitching staff has a 3.20 ERA and 1.16 WHIP. Cody Bellinger is the team’s best hitter with a .266 batting average. Ben Rice leads the team in RBI with 97, adding a team-high 41 home runs.

Brendan Beck (R) is the projected starting pitcher for the Yankees, and he has a 0-1 record, 8.22 ERA and 1.57 WHIP.

Baltimore Orioles Preview

The Baltimore Orioles have a 78-81 record this season and are sitting in the 4th place of the AL East. They have a 39-39 away record and are coming off a 4-2 home win against the Blue Jays.

The Baltimore Orioles have a .233 batting average this season, .313 OBP and .394 Slugging percentage. Baltimore’s pitching staff has a 4.08 ERA and 1.34 WHIP. Pete Alonso is the team’s best hitter with a .264 batting average, leading the team in RBI with 110 and adding a team-high 41 home runs.

Trevor Rogers (L) is the projected starting pitcher for the Orioles, and he has a 10-11 record, 4.07 ERA and 1.18 WHIP.

Baltimore Orioles @ New York Yankees Betting Trends: September 25, 2026

• Probable Starting Pitcher: TBD

Why the New York Yankees will win

• The Yankees have won each of their last nine home games against the Orioles.
• The Orioles have lost 10 of their last 11 games at Yankee Stadium.
• The Yankees have covered the run line each of their last eight night games against teams that held a losing record.
• The Orioles have failed to cover the run line in nine of their last 10 road games against the Yankees following a home win.
• The Orioles have trailed after 3 innings in each of their last seven games at Yankee Stadium.
• The Orioles have lost the first inning in six of their last seven games at Yankee Stadium.
• The Yankees have led after 5 innings in each of their last eight night games against opponents that held a losing record.

• Probable Starting Pitcher: Brandon Young      Record this season: 9-5      ERA: 3.62
• Road Record: 7-1
• Last 5 against Yankees: 0-0

Why the Baltimore Orioles will win

• The Orioles have won each of their last seven games as underdogs against AL opponents following a home win.
• The Yankees have lost five of their last six games as home favorites against AL opponents following a home win.
• The Orioles have covered the run line in each of their last seven games as underdogs against AL opponents following a home win.
• The Yankees have failed to cover the run line in five of their last six games as favorites against AL East opponents following a home win.
• The Orioles have led after 5 innings in five of their last six road games against opponents that held a winning record.
• The Orioles have led after 3 innings in three of their last four road night games.

Total Runs Facts

• Each of the Yankees’ last nine night games against AL opponents have gone OVER the total runs line.
• Each of the Orioles’ last six games as underdogs against the Yankees have gone UNDER the total runs line.
• There has been at least one run scored in the first inning in nine of the Orioles’ last 10 games at Yankee Stadium.
• There has been at least one run scored in the first inning in each of the last four night games between the Orioles and Yankees at Yankee Stadium.

New York Yankees Player Prop Facts

• Ben Rice has hit at least one home run in three of his last four home appearances against the Orioles.
• George Lombard Jr. has recorded at least one hit in each of his last eight appearances against AL opponents.
• Ben Rice ranks T3rd in the league in Home Runs (41) this season.

Baltimore Orioles Player Prop Facts

• Pete Alonso has hit at least one home run in four of the Orioles’ last five games as underdogs.
• Pete Alonso has recorded at least one hit in each of the Orioles’ last nine road games against opponents that held a winning record.
• Brandon Young has recorded six or more strikeouts in each of his last three appearances with the Orioles as underdogs.
• Pete Alonso ranks T3rd in the league in Home Runs (41) this season.

Matchup/League Facts

• The Yankees rank 1st in the league for home runs this season (223).
• The Yankees rank 1st in the league for ERA this season (3.20).
• The Orioles rank 28th in the league for batting average this season (.233).
• The Orioles rank 28th in the league for strikeouts against this season (1489).

Orioles vs Yankees Prediction

The Yankees are 8-2 in their last 10 meetings against the Tigers but have lost two of their last three visits in Detroit.

In this Orioles vs Yankees Prediction, the Yankees are coming as -140 home favorites. The Yankees are going for a bullpen game in the first game of the double-header and have been struggling against lefties in their last five games, with just 1.9 runs per game. The Orioles have been in good form, coming off a series sweep against the Blue Jays and Rogers has two earned runs or less in three of his last four starts. On top of that, the Orioles’ bullpen has been in excellent form and as both teams have nothing to play for, I like Baltimore and the plus money in this one in both games of this double-header.