Chicago Cubs (11-8) vs. San Diego Padres (14-3)
April 15, 2025 9:40 pm EDT
The Line: San Diego Padres 120 / Chicago Cubs -142; Over/Under: 7.5
(Get latest betting odds)
In this article, we will formulate a Padres vs Cubs prediction for this MLB game on Tuesday, April 15, at PETCO Park in San Diego, California. Let’s take a look at the prediction for this MLB matchup.
Chicago Cubs Betting Preview
The Chicago Cubs (11-8, 7-4 Away) got revenge for the two-game series defeat to the Los Angeles Dodgers in Tokyo with a series win in Los Angeles. The Cubs stayed in California to take on the Padres but lost Game 1 of that series. Michael Busch led the offense with two RBI in a 10-4 loss, while Jameson Taillon pitched for 5.1 innings in a no-decision, allowing two runs on three hits with four strikeouts and one walk. Nate Pearson took the loss.
This season, the Cubs average 6.44 runs per game (1st in the MLB) on a .256/.348/.439 slash line. Regarding pitching, the Cubs’ staff has a 4.02 ERA (18th) and 1.34 WHIP (21st). Kyle Tucker leads the Cubs with a .307 batting average, five home runs, and 18 RBI this season.
The projected starting pitcher for the Cubs is Shota Imanaga, who has a 2-1 record in four starts this year with a 2.70 ERA and 0.90 WHIP in 23.1 innings.
San Diego Padres Betting Preview
The San Diego Padres (14-3, 11-0 Home) are still the hottest team in baseball. They swept the Colorado Rockies in three games without allowing a single run! San Diego has only one series loss this year, and it was against the Cubs. The Padres beat the Cubs 10-4 in Game 1 of this series, thanks to Fernando Tatis Jr., who hit a couple of homers and had three RBI, while Gavin Sheets and Jose Iglesias contributed with two RBI each. Dylan Cease pitched for 5.2 innings in a no-decision, allowing three runs (two earned) on seven hits with six strikeouts and one walk. Adrian Morejon got the win.
This year, the Padres average 4.56 runs per game (10th in the MLB) on a .283/.348/.423 triple-slash. When it comes to pitching, the Padres’ staff has a 2.68 ERA (2nd) and 1.04 WHIP (2nd). Fernando Tatis Jr. leads the Padres with a .361 batting average, six home runs, and 12 RBI this season.
Randy Vasquez will take the mound for the Padres on Tuesday. The 26-year-old right-hander has a 1-1 record in three starts this season with a 1.72 ERA and 1.21 WHIP in 15.2 innings.
Total Runs Facts
- Eleven of the Cubs’ last 12 games after playing the previous day have gone OVER the total runs line.
- Eight of the Padres’ last 10 home games against NL Central opponents have gone OVER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Cubs’ last seven road games against NL West opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last six night games between the Cubs and Padres at Petco Park.
Matchup/League Facts
- The Padres rank T2nd in the league for steals this season (23).
- The Padres rank 2nd in the league for strikeouts against this season (109).
- The Cubs rank T1st in the league for doubles this season (36).
- The Cubs rank 1st in the league for RBIs this season (117).
Padres vs Cubs Prediction
The Padres won six of the previous ten H2H encounters, including three of the last four. It’s hard to bet on Under, knowing that 13 of 18 Cubs’ games went Over this season, but this pitching matchup has written Under all over it. Shota Imanaga allowed a .143 BA in 42 at-bats against the Padres, while Randy Vasquez allowed a .152 BA in 33 at-bats against the Cubs. Imanaga didn’t have the best of starts against Texas but will bounce back in this one. Go with Under.
