Padres vs Giants Prediction 8/13/25 MLB Picks Today

In this article, we will formulate a Padres vs Giants Prediction for this MLB game on Wednesday, August 13^th at the Oracle Park in the third game of this series, with the Padres having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

San Francisco Giants Preview

The San Francisco Giants have a 59-61 record this season and are sitting on the third place of the NL West. They have a 29-30 home record and are 54-61 in over/under. They are coming off a 1-5 home defeat by the Padres, and have four consecutive losses. Under is 5-0-1 in their last 6 games and are playing the Padres and the Rays next.

The Giants have a .233 batting average this season, .310 OBP and .374 Slugging percentage. San Francisco’s pitching staff has a 3.66 ERA and 1.28 WHIP.  Heliot Ramos leads the Giants with 123 hits and is the team’s best hitter, with a .268 batting average. Willy Adames leads the team in RBI with 61, adding a team-high 18 home runs.

Kai-Wei Teng (R) is the projected starting pitcher for the Giants, and he has a 1-1 record, 5.40 ERA and 1.32 WHIP.

San Diego Padres Preview

The San Diego Padres have a 68-52 record this season and are sitting on the second place of the NL West. They have a 30-32 road record, and are 50-67 in over/under. The Padres are coming off a 5-1 road victory over the Giants, and are 6-1 in their last 7 games. Over is 6-4 in their last 10 games and are playing the Dodgers and the Giants next.

The Padres have a .251 batting average this season, .321 OBP and .382 Slugging percentage. San Diego’s pitching staff has a 3.57 ERA and 1.21 WHIP.  Manny Machado leads the Padres with 137 hits and team-high .297 batting average. He also leads the team in RBI, with 72, adding a team-high 20 home runs.

Nick Pivetta (R) is the projected starting pitcher for the Padres, and he has a 11-4 record, 2.94 ERA and 0.96 WHIP.

Why the San Francisco Giants will win

• The underdogs have won seven of the Giants’ last eight games at Oracle Park.
• The Padres have lost five of their last six games as road favorites against National League opponents following a win.
• The Padres have failed to cover the run line in each of their last eight games as favorites following a road win.
• The underdogs have covered the run line in each of the Padres’ last seven games at Oracle Park.
• The Padres have trailed after 5 innings in each of their last five games as road favorites against National League opponents.
• The Padres have lost the first inning in five of their last six road games against National League opponents that held a losing record.
• The Padres have trailed after 3 innings in four of their last five games as road favorites against National League opponents.

Why the San Diego Padres will win

• The Giants have lost each of their last 12 home games after playing the previous day.
• The Padres have won each of their last six games after playing the previous day.
• The Giants have failed to cover the run line in each of their last 10 home games after playing the previous day.
• The Padres have covered the run line in nine of their last 10 day games against National League opponents.
• The Padres have led after 5 innings in each of their last four day games.
• The Padres have won the first inning in six of their last seven games as favorites against the Giants at Oracle Park.
• The Padres have led after 3 innings in six of their last seven games at Oracle Park against NL West opponents that held a losing record.

Total Runs Facts

• Thirteen of the last 15 games between the Padres and Giants at Oracle Park have gone UNDER the total runs line.
• Six of the Padres’ last seven road games against NL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Padres’ last seven games as road favorites against NL West opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Giants’ last five games as home underdogs.

Matchup/League Facts

• The Giants rank 1st in the league for home runs allowed this season (105).
• The Giants rank 29th in the league for steals this season (52).
• The Padres rank 1st in the league for hits allowed this season (895).
• The Padres rank 29th in the league for home runs this season (102).

Padres vs Giants Prediction

The Padres are 9-2 in their last 11 meetings against the Giants, and are 6-2 in their 8 meetings this season. They are also 7-2 in their last 9 visits in San Francisco, and under is 5-1 in their last 6 meetings.

In this Padres vs Giants Prediction, the Padres are coming as -160 road favorites. San Diego has a better record and has been in far better form lately, and are putting arguably their best pitcher on the mound, in Pivetta, who has been excellent this season, with a sub 3.00 ERA and sub 1.00 WHIP. I certainly don’t trust Kai-Wei Teng for the Giants, so there is a huge pitching advantage for the Padres in this one. I’ll take the bullpens out of the picture and take the San Diego Padres on the runline in the first 5 innings of this game.