Padres vs Yankees Prediction 9/5/26 MLB Picks Today
NY Yankees (80-61) vs. San Diego Padres (74-67)
September 5, 2026 7:15 pm EDT
The Line: San Diego Padres -114 / NY Yankees -106; Over/Under: 8
(Get latest betting odds)
The New York Yankees and San Diego Padres meet Saturday in MLB action at Yankee Stadium. Here’s a Padres vs Yankees Prediction. This article will include a Padres vs Yankees Pick.
New York Yankees Betting Preview
The New York Yankees are 80-61 this year and play the Rockies and Mets next. The New York Yankees are batting .233 on the season, with a .311 OBP and a .408 slugging percentage. The New York Yankees’ pitching staff has a 3.23 ERA and a 1.17 WHIP. Ben Rice leads the New York Yankees with 130 hits and 88 RBI, while Cody Bellinger and Jazz Chisholm Jr. have combined for 216 hits and 115 RBI.
Carlos Rodon gets the ball for the New York Yankees, and he is 4-3 with a 3.20 ERA and 63 strikeouts this season. Rodon is 2-2 with a 2.27 ERA and 27 strikeouts in his career against the San Diego Padres.
San Diego Padres Betting Preview
The San Diego Padres are 74-67 on the year and play the Nationals and Giants next. The San Diego Padres are batting .237 on the season, have a .314 OBP, and have a .386 slugging percentage. The San Diego Padres’ pitching staff has a 3.91 ERA and a 1.29 WHIP. Fernando Tatis Jr. leads the San Diego Padres with 154 hits and 70 RBI, while Jackson Merrill and Manny Machado have combined for 239 hits and 145 RBI.
Robbie Ray gets the ball for the San Diego Padres, and he is 11-7 with a 3.14 ERA and 126 strikeouts this season. Ray is 2-4 with a 3.89 ERA and 41 strikeouts in his career against the New York Yankees.
Why the San Diego Padres will win
- The Padres have won each of their last six home games against AL opponents.
- The Yankees have lost five of their last six road games against NL West opponents that held a winning record.
- The Padres have covered the run line in each of their last seven-day games against AL East opponents.
- The Yankees have failed to cover the run line in five of their last six games against NL opponents that held a winning record.
- The Padres have led after 3 innings in four of their last five home day games.
Why the New York Yankees will win
- The Yankees have won each of their last six games following a loss.
- The Padres have lost four of their last five games as favorites against AL East opponents.
- The Padres have failed to cover the run line in 12 of their last 13 games as favorites against AL East opponents.
- The Yankees have covered the run line in seven of their last eight games after going to extra innings.
- The Yankees have led after 5 innings in four of their last five games as underdogs against NL West opponents.
- The Yankees have led after 3 innings in four of their last five day games against the Padres.
Total Runs Facts
- Each of the Yankees’ last six road games after going to extra innings have gone UNDER the total runs line.
- Each of the Padres’ last four home games have gone UNDER the total runs line.
- There has been no run scored during the first inning in each of Robbie Ray’s last eight home appearances as a starter.
- There has been no run scored during the first inning in each of the Yankees’ last six games against NL opponents.
San Diego Padres Player Prop Facts
- Fernando Tatis Jr. has recorded at least one hit in each of the Padres’ last nine games as favorites against AL opponents.
- Jackson Merrill has hit a home run in four of the Padres’ last five games as home favorites against AL opponents.
New York Yankees Player Prop Facts
- Ben Rice has recorded at least one hit in each of his last nine appearances against NL West opponents.
- Spencer Jones has hit a home run in each of the Yankees’ last two games as road underdogs against NL opponents.
- Carlos Rodon has recorded six or more strikeouts in four of his last five appearances against NL opponents.
Matchup/League Facts
- The Padres rank 3rd in the league for steals this season (138).
- The Padres rank 26th in the league for hits this season (1096).
- The Yankees rank 1st in the league for ERA this season (3.24).
- The Yankees rank 1st in the league for runs allowed this season (521).
Padres vs Yankees Prediction
The Yankees and Rodon are worth a look at a low price, but I’m going to side with the Padres. Ray was brought to San Diego for spots like this to clinch a playoff spot and to make a deep run. Ray has allowed 20 hits and 10 runs through 26.1 innings since coming from San Francisco. We’re getting a pick em price; I’m going to side with the Padres at home.