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Pirates vs Nationals Prediction 9/14/25 MLB Picks Today

Pirates vs Nationals
September 14, 2025 11:35 am EDT
The Line: Nationals -115 / Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a Pirates vs Nationals Prediction for this MLB game on Sunday, September 14th at the Nationals Park the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Washington Nationals Preview

The Washington Nationals have a 61-87 record this season and are sitting on the last place of the NL East. The Nationals have a 30-43 home record and are 75-64 in over/under. They are coming off a 1-5 home defeat by the Pirates, and are 1-3 in their last 4 games. Over is 7-3 in their last 10 games and are playing the Mets and the Braves next.

The Nationals have a .244 batting average this season, .307 OBP and .389 Slugging percentage. Washington’s pitching staff has a 5.29 ERA and 1.43 WHIP. James Wood leads the Nationals with 143 hits, while CJ Abrams is the team’s best hitter with a .264 batting average. James Wood adds a team-high 88 RBI and leads the team in home runs, with 27.

Cade Cavalli (R) is the projected starting pitcher for the Nationals, and he has a 3-1 record, 4.67 ERA and 1.47 WHIP.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 65-84 record this season and are sitting on the last place of the NL Central. They have a 23-51 road record, and are 60-84 in over/under. They are coming off a 5-1 road win over the Nationals, that ended their six-game losing streak. Under is 6-1 in their last 7 games are playing the Cubs and the Athletics next.

The Pirates have a .232 batting average this season, .305 OBP and .349 slugging percentage. Pittsburgh’s pitching staff has a 3.87 ERA and 1.22 WHIP. Bryan Reynolds leads the Pirates with 133 hits, and a team-high 71 RBI. He is also the team’s best hitter with a .244 batting average, while Oneil Cruz leads the team in home runs, with 19.

Mike Burrows (R) is the projected starting pitcher for the Pirates, and he has a 2-4 record, 3.99 ERA and 1.24 WHIP.

Pittsburgh Pirates @ Washington Nationals Betting Trends: September 14, 2025

 

  • Probable Starting Pitcher: Cade Cavalli      Record this season: 3-1      ERA: 4.67
  • Home Record: 2-0
  • Last 5 against Pirates: –

Why the Washington Nationals will win

  • The Pirates have lost each of their last seven road games against NL East opponents following a win.
  • The Nationals have won six of their last seven home games against National League opponents.
  • The Nationals have covered the run line in each of their last five day games against National League opponents following a loss.
  • The Pirates have failed to cover the run line in each of their last four games against the Nationals following a win.
  • The Nationals have led after 3 innings in three of their last four games as favorites.
  • The Nationals have led after 5 innings in three of their last four games as favorites.

 

  • Probable Starting Pitcher: Mike Burrows      Record this season: 2-4      ERA: 3.99
  • Road Record: 0-1
  • Last 5 against Nationals: –

Why the Pittsburgh Pirates will win

  • The Pirates have won each of their last five games as underdogs against NL East opponents.
  • The Nationals have lost each of their last nine Sunday home games.
  • The Nationals have failed to cover the run line in each of their last six day games against NL Central opponents following a home loss.
  • The Pirates have covered the run line in each of their last five games as underdogs against NL East opponents.
  • The Pirates have led after 3 innings in five of their last six games against NL East opponents.
  • The Pirates have won the first inning in three of their last four games as road underdogs against National League opponents.
  • The Nationals have trailed after 5 innings in each of their last 10 Sunday home games.

Total Runs Facts

  • Each of the Nationals’ last six day games as favorites have gone UNDER the total runs line.
  • Six of the Pirates’ last seven games as road underdogs have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Nationals’ last four games as favorites against National League opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Pirates’ last six road games against NL East opponents.

Washington Nationals Player Prop Facts

  • Josh Bell has hit a home run in three of his last five appearances in day games against NL Central teams that held a losing record.
  • Josh Bell has recorded at least one Double in each of his last three appearances with the Nationals as favorites against NL Central opponents.
  • Josh Bell has recorded at least one hit in each of his last 13 appearances with his team as a favorite against NL Central opponents.

Pittsburgh Pirates Player Prop Facts

  • Bryan Reynolds has hit a home run in four of the Pirates’ last six games as underdogs against NL East opponents.
  • Andrew McCutchen has recorded a Double in four of his last five appearances with his team as an underdog against the Nationals.
  • Andrew McCutchen has recorded at least one hit in each of his last 10 Sunday appearances against teams that held a losing record.
  • Oneil Cruz ranks T3rd in the league in Steals (37) this season.

Matchup/League Facts

  • The Nationals rank 29th in the league for ERA this season (5.29).
  • The Nationals rank 29th in the league for opponent batting average this season (.266).
  • The Pirates rank 30th in the league for runs scored this season (537).
  • The Pirates rank 30th in the league for home runs this season (107).

Pirates vs Nationals Prediction

The Pirates are 5-2 in their last 7 meetings against the Nationals, and under is 4-1 in their last 5 meetings.

In this Pirates vs Nationals Prediction, the Nationals are coming as -115 home favorites. Both pitchers have good home/away splits, but Cavalli has been elite at home for the Nationals, with a 1.10 home ERA, and he is 4-1 in his last 5 starts. The Nationals also have a better offense to offer him run support, and they are even better against right-handed pitching. I like the Nationals as slight favorites at home in a bounce-back spot, so take the Washington Nationals on the moneyline in this one.

Nikos Lagouretos's Free Pick: Washington Nationals -115

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