Pirates vs Padres Prediction 4/7/26 MLB Picks Today

In this article we will formulate a Pirates vs Padres prediction for this MLB game on Tuesday, April 7th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 6-4 this year after they lost game one in this series by a score of 5-0 on Monday night. Pittsburgh had plenty of baserunners in the game, but they couldn’t find a big hit and ended up getting shutout. The Pirates recorded seven hits in the game and they were led by Horwitz, who went 2-3 with one walk. Chandler allowed five hits and three earned runs over 4.1 innings for the loss, while Ramirez and Lawrence both allowed one earned run in relief. Prior to this series, Pittsburgh swept the Orioles in three games and won two out of three against the Reds. 

This season, Pittsburgh has a 3.50 ERA with a 1.38 WHIP and a .227 opponent batting average, while they have scored 45 runs with a .239 batting average and a .337 on base percentage. Oneil Cruz has led the Pirates with four home runs and 10 RBIs, while Ryan O’Hearn has added three home runs and 11 RBIs. The projected starting pitcher for Pittsburgh is Paul Skenes, who is 1-1 with a 9.53 ERA and a 1.94 WHIP over 5.2 innings pitched this year. 

San Diego Padres Betting Preview

The San Diego Padres are 5-5 this season after they won game one by a score of 5-0 on Monday. San Diego scored once in the fourth, twice in the fifth, once in the sixth, and once in the eighth in the lopsided win. The Padres recorded 11 hits and they committed one error, while they were led by Merrill, who went 1-4 with one RBI and one walk in the game. Marquez allowed six hits and zero earned runs over 5.0 innings for the win, while Morgan allowed zero hits over 2.0 relief innings. Prior to this series, San Diego won two out of three against the Red Sox, but lost two out of three against the Giants before that. 

This season, San Diego has a 3.74 ERA with a 1.28 WHIP and a .238 opponent batting average, while they have scored 37 runs with a .218 batting average and a .292 on base percentage. Jackson Merrill has led the Padres with two home runs and seven RBIs, while Ramon Laureano has added two home runs and six RBIs. The projected starting pitcher for San Diego is Nick Pivetta, who is 1-1 with a 6.75 ERA and a 1.63 WHIP over 8.0 innings pitched this season. 

Why the Pittsburgh Pirates will win

• The Pirates have won each of their last four night games against NL West opponents following a loss.
• The Padres have lost four of their last five road games against National League opponents following a win.
• The Pirates have covered the run line in each of their last four night games following a loss.
• The Padres have failed to cover the run line in four of their last five road games against National League opponents following a win.
• The Pirates have led after 3 innings in 10 of their last 12 games as favorites against NL West opponents.
• The Pirates have led after 5 innings in nine of their last 10 games as favorites against NL West opponents.

Why the San Diego Padres will win

• The Padres have won each of their last seven road games against the Pirates.
• The Pirates have lost each of their last seven home games against National League opponents.
• The Padres have covered the run line in each of their last nine games as road underdogs against the Pirates.
• The Pirates have failed to cover the run line in each of their last seven home games against National League opponents.
• The Padres have led after 5 innings in seven of their last eight games at PNC Park.

Total Runs Facts

• Each of the Padres’ last six games against NL Central opponents have gone UNDER the total runs line.
• Five of the last six games between the Padres and Pirates have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Padres’ last 11 Tuesday night games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Pirates’ last eight night games.

Pittsburgh Pirates Player Prop Facts

• Oneil Cruz has hit at least one home run in three of the Pirates’ last four games as favorites.
• Brandon Lowe has recorded at least one hit in each of his last nine appearances with his team as a favorite against NL West opponents.
• Oneil Cruz ranks T3rd in the league in Home Runs (4) this season.

San Diego Padres Player Prop Facts

• Manny Machado has hit a home run in two of the Padres’ last three games as underdogs against the Pirates.
• Nick Pivetta has recorded seven or more strikeouts in three of his last four appearances with the Padres as road underdogs.
• Nick Castellanos has recorded at least one hit in each of his last nine appearances at PNC Park against opponents that held a winning record.

Matchup/League Facts

• The Pirates rank 30th in the league for steals this season (1).
• The Pirates rank 4th in the league for home runs this season (12).
• The Padres rank 29th in the league for home runs this season (5).
• The Padres rank 29th in the league for slugging percentage this season (.324).

Pirates vs Padres Prediction 

San Diego comes into this matchup on a three game winning streak and they have scored 5+ runs in three of their last five. The Padres are 3-1 on the road this year, while the Pirates are 3-1 at home. Pittsburgh had their winning streak snapped on Monday, but they have scored 5+ in three of their last five. Both of these starters looked much better in their second outing, but I still think this total is too low with how the offenses are hitting. Take the over here.