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Pirates vs Reds Prediction 3/31/26 MLB Picks Today

Pittsburgh Pirates (1-3) vs. Cincinnati Reds (3-1)
March 31, 2026 6:40 pm EDT
The Line: Cincinnati Reds -105 / Pittsburgh Pirates -115; Over/Under: 9
(Get latest betting odds)

In this article, we will formulate a Pirates vs Reds Prediction for this MLB matchup on Tuesday, March 31st. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Preview

The Cincinnati Reds have a 3-1 record this season and are sitting in the first place of the NL Central. They have a 3-1 home record and are coming off a 2-0 home win over the Pirates. Their previous three games were a 3-2 home win, a 6-5 home win, and a 3-0 home loss to the Red Sox.

The Reds have a .194 batting average this season, .295 OBP and .310 Slugging percentage. Cincinnati’s pitching staff has a 2.37 ERA and 1.32 WHIP. Sal Stewart is the team’s best hitter with a .667 batting average. Eugenio Suarez leads the team in RBI with 4, also adding a team-high one home run.

Brandon Williamson (L) is the projected starting pitcher for the Reds, and last season he had a 0-0 record, 3.77 ERA and 1.05 WHIP.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 1-3 record this season and are sitting in the last place of the NL Central. They have a 1-3 road record and are coming off a 2-0 road loss to the Reds. Their previous three games were a 4-3 road win, a 4-2 road loss, and an 11-7 road loss to the Mets.

The Pirates have a .223 batting average this season, .307 OBP and .338 Slugging percentage. Pittsburgh’s pitching staff has a 4.25 ERA and 1.42 WHIP. Ryan O’Hearn is the team’s best hitter with a .438 batting average. Brandon Lowe leads the team in RBI with 4, also adding a team-high three home runs.

Bubba Chandler (R) is the projected starting pitcher for the Pirates, and last season he had a 4.02 ERA and 0.93 WHIP.

Pittsburgh Pirates @ Cincinnati Reds Betting Trends: March 31, 2026

 

  • Probable Starting Pitcher: Brandon Williamson      Record this season: –      ERA: –
  • Home Record: –
  • Last 5 against Pirates: 0-0

Why the Cincinnati Reds will win

  • The Pirates have lost eight of their last 10 games as road favorites against National League opponents.
  • The Reds have won four of their last five games as home underdogs.
  • The Pirates have failed to cover the run line in each of their last six games as road favorites against NL Central opponents following a loss.
  • The Reds have covered the run line in seven of their last eight games as home underdogs against the Pirates following a win.
  • The Reds have won the first inning in five of their last six games as home underdogs against NL Central opponents.
  • The Reds have led after 3 innings in 11 of their last 14 games as home underdogs against NL Central opponents.
  • The Pirates have trailed after 5 innings in 12 of their last 16 games at Great American Ball Park against opponents that held a winning record.

 

  • Probable Starting Pitcher: Bubba Chandler      Record this season: –      ERA: –
  • Road Record: –
  • Last 5 against Reds: –

Why the Pittsburgh Pirates will win

  • The Reds have lost each of their last seven Tuesday games against National League opponents that held a losing record.
  • The Pirates have won four of their last five night games against National League opponents.
  • The Pirates have covered the run line in each of their last 10 Tuesday games against the Reds.
  • The Reds have failed to cover the run line in nine of their last 11 night games against NL Central opponents that held a losing record.
  • The Reds have trailed after 5 innings in each of their last three games as underdogs against National League opponents.

Total Runs Facts

  • Seven of the Pirates’ last eight night games against NL Central opponents have gone UNDER the total runs line.
  • Five of the last six games between the Pirates and Reds at Great American Ball Park have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Reds’ last nine games against NL Central opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Pirates’ last nine games as road favorites against NL Central opponents.

Cincinnati Reds Player Prop Facts

  • Spencer Steer has hit at least one home run in each of the Reds’ last two games as home underdogs against NL Central opponents.
  • Elly De La Cruz has recorded at least one hit in each of the Reds’ last 10 games as underdogs against NL Central opponents.
  • Sal Stewart ranks T2nd in the league in Hits (8) this season.

Pittsburgh Pirates Player Prop Facts

  • Brandon Lowe has hit a home run in four of his last six appearances after playing the previous day.
  • Brandon Lowe has recorded at least one hit in each of his last 11 road appearances against NL opponents that held a winning record.
  • Brandon Lowe ranks T2nd in the league in Home Runs (3) this season.

Matchup/League Facts

  • The Reds rank T3rd in the league for triples this season (1).
  • The Reds rank 3rd in the league for runs allowed this season (10).
  • The Pirates rank T26th in the league for walks allowed this season (21).
  • The Pirates rank T24th in the league for steals this season (1).

Pirates vs Reds Prediction

Both teams are tied 4-4 in their last 8 meetings and are 2-2 in their last four meetings in Cincinnati. Under is 7-2-1 in their last 10 meetings.

In this Pirates vs Reds Prediction, the Pirates are coming as -115 road favorites. The Reds have now won three straight games, while the Pirates have won only once this season. The Pirates were the second-worse team against left-handed pitching last season and also have a weaker bullpen than the Reds and I certainly don’t trust Bubba Chandler to lead them to a road victory. The Reds’ bats might have been struggling but they allow just 2.5 runs per game, so take them on the moneyline at home in this one.

Nikos Lagouretos's Free Pick: Cincinnati Reds ML

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