Pirates vs White Sox Prediction 7/19/25 MLB Picks Today

In this article, we will formulate a Pirates vs White Sox prediction for this MLB game on Saturday, July 19th at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 39-59 this year after they lost game one by a score of 10-1 on Friday night. Pittsburgh cut the deficit to 4-1 in the fourth inning, but they failed to score over the last five innings in the loss. The Pirates recorded five hits in the game, and they were led by Cruz, who went 2-3 with one RBI in the loss. Pittsburgh started Falter, who allowed six hits and four earned runs over 4.0 innings for the loss, while Ramirez allowed four earned runs in relief.  

Prior to this series, the Pirates lost two out of three against the Twins and were swept by the Royals in three games. Pittsburgh has lost nine of its last ten games, and they are currently last in the NL Central standings. The Pittsburgh pitching staff has a 3.80 ERA with a 1.21 WHIP and a .235 opponent batting average, while their offense has scored 327 runs with a .229 batting average and a .299 on-base percentage this season. Oneil Cruz has led Pittsburgh with 16 home runs and 38 RBIs, while Bryan Reynolds has added 10 home runs and 46 RBIs this year. The projected starting pitcher for Pittsburgh is Mike Burrows, who is 1-3 with a 4.83 ERA and a 1.46 WHIP over 41.0 innings pitched this year. 

Chicago White Sox Betting Preview

The Chicago White Sox are 33-65 this season after they won game one easily on Friday night. Chicago jumped out to a 3-0 lead in the first inning, and they never looked back in the blowout win. The White Sox recorded 11 hits in the game, and they were led by Taylor, who went 1-4 with three RBIs in the win. Chicago started Cannon, who allowed five hits and one earned run over 7.0 innings for the win, while Alexander and Altavilla closed out the win. 

Prior to this series, the White Sox lost three out of four against the Guardians and two out of three against the Blue Jays. Chicago has lost six of their last nine games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.12 ERA with a 1.37 WHIP and a .251 opponent batting average, while the offense has scored 342 runs with a .221 batting average and a .296 on-base percentage this season. Miguel Vargas has led Chicago with 10 home runs and 35 RBIs, while Andrew Benintendi has added 11 home runs and 37 RBIs this year. The projected starting pitcher for Chicago is Adrian Houser, who is 5-2 with a 1.56 ERA and a 1.13 WHIP over 57.2 innings pitched this season. 

Why the White Sox will beat the Pirates

• The Pirates have lost each of their last seven night games against American League opponents.
• The White Sox have won seven of their last eight night games against teams that held a losing record.
• The Pirates have failed to cover the run line in each of their last eight home games against AL Central opponents.
• The road team has covered the run line in each of the last six games between the White Sox and Pirates.
• The White Sox have led after 5 innings in seven of their last eight night games against National League opponents that held a losing record.
• The Pirates have trailed after 3 innings in seven of their last eight home games against American League opponents that held a losing record.
• The White Sox have won the first inning in three of their last four road games against NL Central opponents.

Total Runs Facts

• Five of the Pirates’ last six night games after playing the previous day have gone UNDER the total runs line.
• Four of the White Sox’s last five games against NL Central opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the White Sox’s last seven games as road underdogs against National League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 14 of the Pirates’ last 16 games as favorites.

Pittsburgh Pirates Player Prop Facts

• Tommy Pham has hit a home run in four of his last 10 appearances in night games against AL teams that held a losing record.
• Bryan Reynolds has recorded at least one hit in each of the Pirates’ last 14 home games against AL Central opponents.
• Andrew McCutchen has recorded a Double in each of his last four appearances against the White Sox after playing the previous day.

Chicago White Sox Player Prop Facts

• Luis Robert has hit a home run in each of his last two appearances with the White Sox against NL opponents.
• Adrian Houser has recorded four or more strikeouts in each of his last four appearances in night games against NL Central teams that held a losing record.
• Mike Tauchman has recorded at least one hit in each of his last 10 road appearances against opponents that held a losing record.
• Michael A. Taylor has recorded a Double in each of his last three appearances with the White Sox as underdogs against NL opponents.
• Adrian Houser has recorded a win in each of his last three appearances.

Pirates vs White Sox Prediction 

Chicago was able to pick up an easy win on Friday night to start this series, as Pittsburgh continues to really struggle over the last two weeks. The Pirates are 26-22 at home this year, while the White Sox are 12-36 on the road. Neither team is hitting the ball very well right now, but Houser has allowed a total of three earned runs over his last four starts (28.1 IP). On the other side, Burrows has been decent at times, but allowed six earned runs in his last start. Take the White Sox to get another win here.