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Rangers vs Pirates Prediction 4/22/26 MLB Picks Today

Pittsburgh Pirates (13-10) vs. Texas Rangers (12-11)
April 22, 2026 8:05 pm EDT
The Line: Texas Rangers 0.0001 / Pittsburgh Pirates 0.0001; Over/Under: 0.0001
(Get latest betting odds)

The Pittsburgh Pirates and Texas Rangers meet Wednesday in MLB action at Globe Life Field. Here’s a Rangers vs. Pirates Prediction. This article will include a Rangers vs. Pirates Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 13-10 on the year and play the Brewers and Cardinals next. The Pittsburgh Pirates are batting .250 on the season and have a .337 OBP, and a .393 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 3.31 ERA and a 1.29 WHIP. Oneil Cruz leads the Pittsburgh Pirates with 27 hits and 19 RBI, while Ryan O’Hearn and Bryan Reynolds have combined for 45 hits and 31 RBI.

Braxton Ashcraft gets the ball for the Pittsburgh Pirates, and he is 1-1 with a 2.38 ERA and 27 strikeouts this season. This will be Ashcraft’s second career game against the Texas Rangers.

Texas Rangers Betting Preview

The Texas Rangers are 12-11 on the year and play the Athletics and Yankees next. The Texas Rangers are batting .240 on the season and have a .317 OBP, and a .393 slugging percentage. The Texas Rangers pitching staff has a 3.45 ERA and a 1.27 WHIP. Brandon Nimmo leads the Texas Rangers with 28 hits and 11 RBI, while Jake Burger and Josh Jung have combined for 44 hits and 26 RBI.

Jack Leiter gets the ball for the Texas Rangers, and he is 1-1 with a 4.87 ERA and 24 strikeouts this season. This will be Leiter’s second career game against the Pittsburgh Pirates.

Why the Texas Rangers will win

  • The Pirates have lost each of their last five road games against American League opponents.
  • The Rangers have won each of their last four home games.
  • The Rangers have covered the run line each of their last five games against teams that held a winning record.
  • The Rangers have led after 3 innings in each of their last four games against the Pirates.
  • The Rangers have led after 5 innings in five of their last six night games against NL Central opponents.

Why the Pittsburgh Pirates will win

  • The Pirates have won each of their last eight games following a loss.
  • The Rangers have lost six of their last seven home games against National League opponents.
  • The Pirates have covered the run line in each of their last eight games following a loss.
  • The Rangers have failed to cover the run line in seven of their last eight night games against the Pirates following a win.
  • The Pirates have won the first inning in four of their last five games against American League opponents.
  • The Pirates have led after 3 innings in each of their last five games against opponents that held a winning record.
  • The Pirates have led after 5 innings in each of their last six Wednesday night games against AL West opponents that held a winning record.

Total Runs Facts

  • Each of the Rangers’ last 12 home games has gone UNDER the total runs line.
  • Each of the Pirates’ last seven night games against American League opponents has gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rangers’ last six night games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Pirates’ last six Wednesday games against AL West opponents.

Texas Rangers Player Prop Facts

  • Jake Burger has hit at least one home run in two of the Rangers’ last three night games against opponents that held a winning record.
  • Brandon Nimmo has recorded at least one hit in each of his last nine appearances against the Pirates after playing the previous day.

Pittsburgh Pirates Player Prop Facts

  • Bryan Reynolds has hit a home run in each of the Pirates’ last two road games against opponents that held a winning record.
  • Brandon Lowe has recorded at least one hit in each of his last 11 appearances in night games against AL West teams that held a winning record.
  • Oneil Cruz ranks T2nd in the league in Steals (10) this season.

Matchup/League Facts

  • The Rangers rank 5th in the league for runs allowed this season (83).
  • The Rangers rank 24th in the league for strikeouts against this season (219).
  • The Pirates are one of only four teams in the league to rank top 10 in both steals and batting average this season.
  • The Pirates rank 4th in the league for ERA this season (3.31).

Rangers vs Pirates Prediction

The Pirates have had issues stringing wins together but you can say the same about the Rangers. The Rangers probably get the edge because they’re at home, but I’m leaning toward the Pirates. Leiter still has yet to find his footing on the big stage. Ashcraft has been great through 22.2 innings with a 2.38 ERA and 1.06 WHIP, and he has 27 strikeouts. Leiter has issues with control and when he gets hit, he usually gets hit hard. You’re giving me a pick ’em price; I’ll lean toward the Pirates with the pitcher in better form.

Randy Chambers's Free Pick: Pittsburgh Pirates

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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