Rays vs Blue Jays Prediction 9/15/25 MLB Picks Today

The Tampa Bay Rays and Toronto Blue Jays meet on Monday in MLB action from the George M. Steinbrenner Field. Here’s a Rays vs Blue Jays prediction. We will look at this from a betting perspective and determine the best Rays vs Blue Jays pick.

What a Dominant Game for the Blue Jays

It was a dominant game for the Blue Jays on Sunday against the Baltimore Orioles, and they scored 11 runs on the way to the victory. It was actually a lot closer than it looked, but six runs in the 7th inning ended up being the difference. Ernie Clement had a strong game finishing with two hits and three runs driven in. Shane Bieber also had a solid game on the mound going six innings giving up four hits and one run. 

The Blue Jays are averaging 5.03 runs while their pitching is giving up 4.45 runs per game. The offense is ranked 4th while the pitching is ranked 19th. As a team, they are batting .269 which is the best in all of baseball. Getting the start for the Blue Jays will be Trey Yesavage and there is a whole lot of buzz surrounding him for this start. He was the 20th overall pick in the 2024 draft, and the hope is that he’s going to be a starting pitcher for a very long time for this team.

Why the Blue Jays WIll Beat the Rays

• The Rays have lost seven of their last eight games after playing the previous day.
• The Blue Jays have won seven of their last eight night games against AL East opponents following a win.
• The Rays have failed to cover the run line in each of their last six games against American League opponents.
• The Blue Jays have covered the run line in five of their last six road games.

Rays Have Blown It

The Rays had their backs against the wall heading into the last week, and they knew to make the playoffs it was going to take a near perfect week. It was far from that and they lost two of three against the Chicago White Sox and the Chicago Cubs. On Sunday, the Rays scored three runs against the Cubs, but they gave up four and that led to the defeat. Adrian Houser went six innings giving up seven hits and two runs. 

The Rays are averaging 4.47 runs while their pitching is giving up 4.15 runs per game. The offense is ranked 13th while the pitching is ranked 10th. At the time of this article being written, there was no starting pitcher for the Rays announced. 

Why the Rays Will Beat the Blue Jays

• The Rays have won each of their last six night games against the Blue Jays following a loss.
• The Blue Jays have lost 11 of their last 12 games against the Rays following a win.
• The Rays have covered the run line in nine of their last 10 night games against AL East opponents following a road loss.
• The Blue Jays have failed to cover the run line in seven of their last eight road games against American League opponents that held a losing record.
• The Blue Jays have trailed after 3 innings in four of their last five road games against American League opponents that held a losing record.
• The Blue Jays have trailed after 5 innings in six of their last eight road games against American League opponents.

Rays vs Blue Jays Prediction

I do have a little bit of a concern about Yesavage and the nerves, but the one thing I don’t have concern about is his talent, and he’s going to have a dominant start. The Rays are averaging 4.47 runs per game, but they aren’t going to reach that number here. Look for Yesavage to go at least six innings, and the Rays aren’t going to have many quality at bats. The Blue Jays will score at least four or five runs, and Toronto will get the job done. Back the Blue Jays on the money line.