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Rays vs Blue Jays Prediction 9/17/25 MLB Picks Today

Toronto Blue Jays (89-62) vs. Tampa Bay Rays (73-78)
September 17, 2025 7:05 pm EDT
The Line: Tampa Bay Rays 107 / Toronto Blue Jays -131; Over/Under: 8
(Get latest betting odds)

The Toronto Blue Jays and Tampa Bay Rays meet Wednesday in MLB action at George M. Steinbrenner Field. Here’s a Rays vs Blue Jays Prediction. This article will include a Rays vs Blue Jays Pick.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 89-62 on the year and play the Royals, Red Sox, and Rays next. The Toronto Blue Jays are batting .269 on the season, have a .337 OBP, and a .432 slugging percentage. The Toronto Blue Jays pitching staff has a 4.13 ERA and a 1.26 WHIP. Bo Bichette leads the Toronto Blue Jays with 181 hits and 94 RBI, while Vladimir Guerrero Jr. and Ernie Clement have combined for 306 hits and 147 RBI.

Kevin Gausman gets the ball for the Toronto Blue Jays, and he is 10-10 with a 3.44 ERA and 171 strikeouts this season. Gausman is 8-9 with a 4.02 ERA and 134 strikeouts in his career against the Tampa Bay Rays.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 73-78 on the year and play the Red Sox, Orioles, and Blue Jays next. The Tampa Bay Rays are batting .251 on the season, have a .313 OBP, and a .403 slugging percentage. The Tampa Bay Rays pitching staff has a 3.88 ERA and a 1.21 WHIP. Yandy Diaz leads the Tampa Bay Rays with 165 hits and 80 RBI while Junior Caminero and Brandon Lowe have combined for 273 hits and 187 RBI.

Ian Seymour gets the ball for the Tampa Bay Rays, and he is 3-2 with a 3.16 ERA and 52 strikeouts this season. This will be Seymour’s first career game against the Toronto Blue Jays.

Toronto Blue Jays @ Tampa Bay Rays Betting Trends: September 17, 2025

 

  • Probable Starting Pitcher: Ian Seymour      Record this season: 3-2      ERA: 2.95
  • Home Record: 0-1
  • Last 5 against Blue Jays: –

Why the Tampa Bay Rays will win

  • The Blue Jays have lost each of their last five games as favorites against the Rays following a road win.
  • The Rays have won each of their last four games as underdogs against the Blue Jays following a home loss.
  • The Blue Jays have failed to cover the run line in each of their last seven games as road favorites against American League opponents.
  • The Rays have covered the run line in each of their last seven games as underdogs against the Blue Jays following a loss.
  • The Rays have won the first inning in each of their last five games as underdogs.
  • The Rays have led after 5 innings in seven of their last eight games against the Blue Jays.
  • The Rays have led after 3 innings in each of their last four games as home underdogs.

 

  • Probable Starting Pitcher: Kevin Gausman      Record this season: 10-10      ERA: 3.44
  • Road Record: 5-6
  • Last 5 against Rays: 1-2

Why the Toronto Blue Jays will win

  • The Rays have lost each of their last seven games against AL East opponents.
  • The Blue Jays have won each of their last six games.
  • The Rays have failed to cover the run line in each of their last 10 games against American League opponents following a home loss.
  • The Blue Jays have covered the run line in each of their last seven Wednesday games against AL East opponents.
  • The Blue Jays have led after 5 innings in six of their last seven road night games.
  • The Rays have trailed after 3 innings in five of their last six home games against AL East opponents.
  • The Rays have lost the first inning in five of their last six home games against AL East opponents.

Total Runs Facts

  • Five of the Rays’ last six games as home underdogs have gone OVER the total runs line.
  • Five of the Blue Jays’ last six night games against American League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Rays’ last seven home games against AL East opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Blue Jays’ last nine games as road favorites against American League opponents.

Tampa Bay Rays Player Prop Facts

  • Brandon Lowe has hit at least one home run in four of the Rays’ last six games against the Blue Jays.
  • Yandy Diaz has recorded a Double in five of the Rays’ last six games as underdogs against AL opponents.
  • Taylor Walls has recorded at least one hit in each of his last nine appearances against AL East opponents that held a winning record.
  • Chandler Simpson ranks 2nd in the league in Steals (42) this season.

Toronto Blue Jays Player Prop Facts

  • Kevin Gausman has recorded six or more strikeouts in 11 of his last 12 appearances with the Blue Jays as road favorites against AL East opponents.
  • Kevin Gausman has recorded a win in seven of his last nine road appearances against AL opponents that held a losing record.
  • Ernie Clement has recorded a Double in four of his last five road appearances.
  • Daulton Varsho has hit a home run in three of the Blue Jays’ last four games as road favorites.
  • Bo Bichette has recorded at least one hit in each of his last 17 appearances against opponents that held a losing record.
  • George Springer ranks 2nd amongst qualified players for On Base Percentage (.395) this season.

Matchup/League Facts

  • The Rays rank 1st in the league for steals this season (185).
  • The Rays are one of only three teams in the league to rank top 10 in both strikeouts and walks allowed this season.
  • The Blue Jays rank 1st in the league for hits this season (1390).
  • The Blue Jays rank 1st in the league for batting average this season (.269).

Rays vs Blue Jays Prediction

The Blue Jays continue to cash tickets, and they’re getting harder and harder to bet against. Gausman has allowed 10 hits and 2 runs in his last 24 innings. Gausman has a 3.45 ERA and .190 allowed batting average in 91.1 road innings. The Rays have nothing to play for at this point, and they’re looking like it as the losses keep piling up. Seymour has been solid as a rookie, but it doesn’t matter with the way the Rays are playing right now. I’ll ride the hot hand and side with the Blue Jays.

Randy Chambers's Free Pick: Toronto Blue Jays -131

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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