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Rays vs Cubs Prediction 9/14/25 MLB Picks Today

Rays vs Cubs
September 14, 2025 2:20 pm EDT
The Line: Cubs -160 / Over/Under: 7.5
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In this article, we will formulate a Rays vs Cubs Prediction for this MLB game on Sunday, September 14th at the Wrigley Field the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have an 84-64 record this season and are sitting on the second place of the NL Central. The Cubs have a 45-29 home record and are 67-70 in over/under. They are coming off a 4-5 home defeat by the Rays, which ended their three-game winning streak. Under is 6-4 in their last 10 games and are playing the Pirates and the Reds next.

The Cubs have a .248 batting average this season, .320 OBP and .426 Slugging percentage. Chicago’s pitching staff has a 3.867 ERA and 1.19 WHIP. Nico Hoerner leads the Cubs with 160 hits, and he is the team’s best hitter with a .297 batting average. Seiya Suzuki leads the team in RBI, with 91, adding a team-high 28 home runs.

Shota Imanaga (L) is the projected starting pitcher for the Cubs, and he has a 9-7 record, 3.21 ERA and 0.93 WHIP.

Tampa Bay Rays Preview

The Tampa Bay Rays have a 73-75 record this season and are sitting on the 4th place of the AL East. The Rays have a 35-39 road record and are 65-74 in over/under. They are coming off a 5-4 road victory over the Cubs, which ended their three-game losing streak. Over is 9-4 in their last 13 games and are playing the Red Sox and the Blue Jays next.

The Rays have a .252 batting average this season, .313 OBP and .404 slugging percentage. Tampa’s pitching staff has a 3.90 ERA and 1.21 WHIP.  Yandy Diaz leads the Rays with 159 hits, and he is the team’s best hitter with .291 batting average. Junior Caminero leads the team in RBI, with 107 and in home runs, with 43.

Adrian Houser (R) is the projected starting pitcher for the Rays, and he has an 8-4 record, 3.11 ERA and 1.26 WHIP.

Tampa Bay Rays @ the Chicago Cubs Betting Trends: September 14, 2025

 

  • Probable Starting Pitcher: Shota Imanaga      Record this season: 9-7      ERA: 3.21
  • Home Record: 4-2
  • Last 5 against Rays: –

Why the Chicago Cubs will win

  • The Cubs have won eight of their last nine day games against AL East opponents following a home loss.
  • The Rays have lost 14 of their last 16 road games against teams that held a winning record.
  • The Rays have failed to cover the run line in each of their last eight games.
  • The Cubs have covered the run line in eight of their last nine home games against the Rays.
  • The Cubs have led after 3 innings in each of their last nine home games against AL East opponents.
  • The Rays have trailed after 5 innings in nine of their last 10 games against NL Central opponents that held a winning record.

 

  • Probable Starting Pitcher: Adrian Houser      Record this season: 8-4      ERA: 3.11
  • Road Record: 1-4
  • Last 5 against Cubs: 2-0

Why the Tampa Bay Rays will win

  • The Cubs have lost four of their last five games as favorites after playing the previous day.
  • The Rays have won six of their last seven games as road underdogs against National League opponents following a win.
  • The Cubs have failed to cover the run line in each of their last six games as home favorites after playing the previous day.
  • The Rays have covered the run line in seven of their last eight games as road underdogs against National League opponents following a win.
  • The Rays have won the first inning in each of their last three games as underdogs.
  • The Rays have led after 3 innings in three of their last four games as underdogs.

Total Runs Facts

  • Nine of the Rays’ last 10 games as underdogs have gone OVER the total runs line.
  • Five of the Cubs’ last six day games as favorites have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Cubs’ last six games as favorites.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in 14 of the Rays’ last 17 games as road underdogs against NL Central opponents.

Chicago Cubs Player Prop Facts

  • Ian Happ has hit a home run in four of the Cubs’ last seven day games.
  • Ian Happ has recorded a Double in each of the Cubs’ last four games as favorites against AL East opponents.
  • Shota Imanaga has recorded a win in five of his last six home appearances against opponents that held a losing record.
  • Shota Imanaga has recorded six or more strikeouts in four of his five previous appearances against AL East opponents.
  • Nico Hoerner has recorded at least one hit in each of his last nine appearances in day games.
  • Nico Hoerner ranks 8th in the league in Hits (160) this season.

Tampa Bay Rays Player Prop Facts

  • Brandon Lowe has hit a home run in two of his last three appearances with the Rays as road underdogs against NL Central opponents.
  • Brandon Lowe has recorded a Double in four of his last five appearances against opponents that held a winning record.
  • Adrian Houser has recorded a win in four of his last five appearances against opponents that held a winning record.
  • Adrian Houser has recorded five or more strikeouts in three of his last four appearances with his team as an underdog against NL opponents.
  • Brandon Lowe has recorded at least one hit in each of his last 10 Sunday appearances against NL teams that held a winning record.
  • Chandler Simpson ranks 2nd in the league in Steals (40) this season.

Matchup/League Facts

  • The Cubs rank 1st in the league for walks allowed this season (373).
  • The Cubs rank 3rd in the league for steals this season (151).
  • The Rays rank 1st in the league for steals this season (181).
  • The Rays are one of only three teams in the league to rank top 10 in both steals and batting average this season.

Rays vs Cubs Prediction

The Rays are 4-2 in their last 6 meetings against the Cubs, but the Cubs are 3-2 in their last 5 meetings in Chicago. Under is 6-2 in their last 8 meetings.

In this Rays vs Cubs Prediction, the Cubs are coming as -165 home favorites. Both pitchers have been excellent, but the Rays have been terrible against left-handed pitching, that’s why I’m with the Cubs in this one. Imanaga has been slightly better at home, while Houser has been weaker on the road for the Rays, with a 3.54 road ERA, and has 7 earned runs in his last two starts. I don’t expect the Cubs to drop a second straight home game to the Rays, so like them in this bounce-back spot today. Take the Chicago Cubs on the moneyline at home.

Nikos Lagouretos's Free Pick: Chicago Cubs -160

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