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Rays vs Yankees Prediction 9/23/26 MLB Picks Today

Tampa Bay Rays (96-61) vs. NY Yankees (90-67)
September 23, 2026 7:05 pm EDT
The Line: NY Yankees -158 / Tampa Bay Rays 131; Over/Under: 7
(Get latest betting odds)

In this article, we will formulate a Rays vs Yankees Prediction for this MLB matchup on Wednesday, September 23rd in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

New York Yankees Preview

The New York Yankees have a 90-67 record this season and are sitting in the 2nd place of the AL East. They have a 43-33 home record and are coming off a 1-6 home loss against the Rays. They will face the Orioles next.

The New York Yankees have a .234 batting average this season, .310 OBP and .408 Slugging percentage. New York’s pitching staff has a 3.21 ERA and 1.16 WHIP. Cody Bellinger is the team’s best hitter with a .268 batting average. Ben Rice leads the team in RBI with 95, adding a team-high 39 home runs.

Gerrit Cole (R) is the projected starting pitcher for the Yankees, and he has a 9-9 record, 3.63 ERA and 1.10 WHIP.

Tampa Bay Rays Preview

The Tampa Bay Rays have a 96-61 record this season and are sitting in the 1st place of the AL East. They have a 41-35 away record and are coming off a 6-1 road win against the Yankees. They will face the Phillies next.

The Tampa Bay Rays have a .258 batting average this season, .327 OBP and .402 Slugging percentage. Tampa Bay’s pitching staff has a 3.67 ERA and 1.13 WHIP. Chandler Simpson is the team’s best hitter with a .309 batting average. Junior Caminero leads the team in RBI with 97, adding a team-high 41 home runs.

Ian Seymour (L) is the projected starting pitcher for the Rays, and he has a 9-7 record, 4.38 ERA and 1.17 WHIP.

Tampa Bay Rays @ New York Yankees Betting Trends: September 23, 2026

 

  • Probable Starting Pitcher: Gerrit Cole      Record this season: 9-9      ERA: 3.63
  • Home Record: 3-4
  • Last 5 against Rays: 3-1

Why the New York Yankees will win

  • The Yankees have won each of their last 12 home games following a loss.
  • The Rays have lost six of their last seven games against AL East opponents following a win.
  • The Rays have failed to cover the run line in eight of their last nine night games against AL East opponents.
  • The Yankees have covered the run line in seven of their last eight games following a loss.
  • The Yankees have led after 3 innings in five of their last six night games against AL East opponents.
  • The Yankees have led after 5 innings in six of their last seven home night games.

 

  • Probable Starting Pitcher: Ian Seymour      Record this season: 9-7      ERA: 4.38
  • Road Record: 5-2
  • Last 5 against Yankees: 2-0

Why the Tampa Bay Rays will win

  • The Rays have won each of their last six games as underdogs against AL opponents following a road win.
  • The Yankees have lost three of their last four games as favorites.
  • The Rays have covered the run line in each of their last six games as underdogs against AL opponents following a road win.
  • The Yankees have failed to cover the run line in each of their last seven Wednesday home games against AL East opponents.
  • The Rays have led after 3 innings in each of their last four road night games.
  • The Rays have led after 5 innings in each of their last five road night games.

Total Runs Facts

  • Each of the Yankees’ last seven night games against AL opponents have gone OVER the total runs line.
  • Each of the Rays’ last four night games after playing the previous day have gone UNDER the total runs line.
  • There has been no run scored during the first inning in each of the last six night games between the Rays and Yankees.
  • There has been no run scored during the first inning in seven of the Rays’ last eight road games against AL opponents.

New York Yankees Player Prop Facts

  • Austin Wells has hit a home run in three of his last four appearances after playing the previous day.
  • Gerrit Cole has recorded a win in four of his last five appearances against opponents that held a winning record.
  • Gerrit Cole has recorded six or more strikeouts in 22 of his last 24 appearances against the Rays.
  • George Lombard Jr. has recorded at least one hit in each of his last six appearances against AL opponents.
  • Ben Rice ranks T3rd amongst qualified players for Slugging Percentage (.525) this season.

Tampa Bay Rays Player Prop Facts

  • Richie Palacios has hit a home run in three of his last five road appearances.
  • Ian Seymour has recorded seven or more strikeouts in three of his last four appearances against AL East opponents.
  • Junior Caminero has recorded at least one hit in each of the Rays’ last 10 night games.
  • Chandler Simpson ranks 2nd in the league in Steals (46) this season.

Matchup/League Facts

  • The Yankees rank T1st in the league for home runs this season (217).
  • The Yankees rank 1st in the league for ERA this season (3.21).
  • The Rays rank 1st in the league for batting average this season (.258).
  • The Rays rank 1st in the league for strikeouts against this season (1099).

Rays vs Yankees Prediction

Both teams are tied 4-4 in their last 8 meetings and are 2-2 in their last 4 meetings in New York.

In this Rays vs Yankees Prediction, the Yankees are coming as -155 home favorites. Both pitchers have been in bad form, as Cole has given up 3+ runs in four of his last five starts and Seymour 3+ in six of his last seven games played and has a 4.96 road ERA. Both teams have been very efficient against right-handed pitching in their last 10 games with 11.7 runs per game combined and the Yankees are 8-2 to the over in their last 10 games. The total of 7 is too low, so take the over in this one.

Nikos Lagouretos's Free Pick: Over 7

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