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Red Sox vs Blue Jays Prediction 6/28/25 MLB Picks Today

Toronto Blue Jays (44-37) vs. Boston Red Sox (40-43)
June 28, 2025 4:10 pm EDT
The Line: Boston Red Sox +109 / Toronto Blue Jays -132; Over/Under: 9
(Get latest betting odds)

The Toronto Blue Jays and the Boston Red Sox meet Saturday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Red Sox vs Blue Jays Prediction.

Starting Pitching Matchup

The Toronto Blue Jays will send out Chris Bassitt for the start here, and Bassitt is 7-3 with a 3.61 ERA and 90 strikeouts this season. In his last five starts against the Red Sox, Bassitt is 0-2 with a 2.43 ERA and 24 strikeouts. Lucas Giolito will get the nod for the Red Sox for this game and is 3-1 with a 4.53 ERA and 46 strikeouts this season. In his last five starts against the Blue Jays, Giolito is 0-3 with a 7.00 ERA and 27 strikeouts.

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to build on their 9-0 win over the Boston Red Sox last time out to sit at 44-37 on the year. After this series, the Blue Jays will square off against the New York Yankees at home.

Blue Jays Win Back-To-Back Games

George Springer has 66 hits and Bo Bichette has 95 hits, with Springer adding 11 home runs, a triple, 15 doubles and 40 RBIs while Bichette has 19 doubles, 11 home runs, and 49 RBIs. Andres Gimenez has added 39 hits with 7 doubles and 4 home runs and 17 RBIs this season, along with 9 stolen bases, while Anthony Santander has 56 strikeouts so far this season. Vladimir Guerrero Jr. also has 11 homers, 16 doubles, and 40 RBIs, while Springer also has a .267 batting average and 62 strikeouts up to this point in the year. Addison Barger chipped in 17 doubles with 8 home runs and 24 RBIs, and Ernie Clement added 17 doubles as part of his 79 hits this season.

Why the Toronto Blue Jays will win

  • The Red Sox have lost each of their last 10 games as home underdogs against the Blue Jays following a loss.
  • The Blue Jays have won each of their last nine games as road favorites against the Red Sox following a win.
  • The Blue Jays have covered the run line in each of their last six games at Fenway Park.
  • The Red Sox have failed to cover the run line in each of their last six day games against the Blue Jays at Fenway Park following a home loss.

Toronto Blue Jays Player Prop Facts

  • Vladimir Guerrero Jr. has hit a home run in each of the Blue Jays’ last two games as road favorites against the Red Sox.
  • Ernie Clement has recorded two or more hits in each of the Blue Jays’ last eight games as favorites against AL opponents.
  • Chris Bassitt has recorded six or more strikeouts in each of his last seven Saturday appearances against AL teams that held a losing record.
  • Daulton Varsho has recorded a Double in four of his last five appearances in day games.

Boston Red Sox Recap

The Boston Red Sox come into this game looking to rebound from their loss at the hands of the Blue Jays last time out to sit at 40-43 on the year. After this series, the Red Sox will square off against the Cincinnati Reds at home.

Red Sox Lose 6 Straight

Alex Bregman has 59 hits, including a team-high 17 doubles, along with 11 home runs and 35 RBIs this season. Trevor Story added 70 hits with 11 home runs, 41 RBIs, and 11 stolen bases, while Jarren Duran has 87 hits with 20 doubles, 8 triples, 5 home runs, 38 RBIs, and a team-high 15 stolen bases. Kristian Campbell added 51 hits with 10 doubles, 6 homers, and 21 RBIs while Wilyer Abreu has 13 home runs with 36 RBIs and 4 stolen bases, and Ceddanne Rafaela has 8 homers, 13 doubles, 2 triples, 30 RBIs, and 11 stolen bases this season.

Why the Boston Red Sox will win

  • The Blue Jays have lost each of their last eight games as favorites against AL East opponents following a win.
  • The Red Sox have won each of their last four games as home underdogs against the Blue Jays.
  • The Blue Jays have failed to cover the run line in each of their last 11 games as favorites against AL East opponents following a win.
  • The Red Sox have covered the run line in each of their last six games as home underdogs against the Blue Jays.

Boston Red Sox Player Prop Facts

  • Lucas Giolito has recorded five or more strikeouts in each of his last eight appearances in day games against AL teams that held a winning record.
  • Alex Bregman has hit a home run in each of his last two appearances against AL opponents that held a winning record.
  • Lucas Giolito has recorded a win in each of his last four appearances against AL opponents that held a winning record.
  • Masataka Yoshida has recorded two or more hits in each of the Red Sox’s last four games as home underdogs against the Blue Jays.

Total Runs Facts

  • Seven of the last eight games between the Blue Jays and Red Sox at Fenway Park have gone UNDER the total runs line.
  • Each of the Blue Jays’ last five day games against AL East opponents have gone OVER the total runs line.

Red Sox vs Blue Jays Prediction

I’m backing the Blue Jays in this one. I know the Red Sox are tempting to look at as a home underdog, but they are just in a funk right now and can’t seem to get out of their own way. Toronto’s been playing the slightly better ball, and Lucas Giolito’s issues this season have come early and often at Fenway Park. I’ll side with the Jays for the win in this one.

Chris Ruffolo's Free Pick: Toronto Blue Jays -132

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Chris Ruffolo

Chris joined the Sports Chat Place team in August 2016 and has a proven system that combines multiple analytical and situational statistics and trends to give out thousands of winning picks over the last three years with winning records across all of the top leagues, Follow Chris Ruffolo on Twitter @ruffthepickdawg

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