
Red Sox vs Cardinals Prediction 4/5/25 MLB Picks Today
St. Louis Cardinals (4-3) vs. Boston Red Sox (4-4)
April 5, 2025 4:10 pm EDT
The Line: Boston Red Sox -122 / St. Louis Cardinals 102; Over/Under: 9
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In this article, we will formulate a Red Sox vs Cardinals Prediction for this MLB game on Saturday, April 5th, at Fenway Park. Let’s take a look at a prediction for the Boston Red Sox vs. St. Louis Cardinals.
Red Sox Offense Impressed
The Red Sox offense impressed on Friday against the Cardinals. At the end of the first inning, they were up 5-0, and they never looked back on the way to the win. Trevor Story was a problem, hitting a home run and driving in three RBIs. Wilyer Abreu also hit a home run and drove in two RBIs. Even though the offense was good, the pitching was a problem, and Walker Buehler went five innings, giving up seven hits and five runs.
The Red Sox are averaging 5.0 runs, while their pitching is giving up 4.25 runs per game. The offense is going to need to get out to a fast start to really put the pressure on. Richard Fitts will get the start, and he sits with a 0-1 record and an ERA of 4.50. Against the Rangers in the last game, he went six innings, giving up six hits and three runs.
Cardinals Pitching Has to be Better
The Cardinals’ pitching has to be a lot better in this game. At the end of the first inning, they were down 5-0, and even though they fought back a bit, they still ended up losing. The 13 hits were impressive, but this game was basically over from the beginning. Erick Fedde only went three innings, and he gave up five hits and six runs. He issued four walks.
Overall, the Cardinals’ offense has been the second-best in the league, averaging 7.29 runs per game. Andre Pallante is going to get the start for the Cardinals, and he sits with a 1-0 record and an ERA of 3.60. Against the Minnesota Twins, he went five innings, giving up four hits and two runs. He did give up a home run.
Why the Cardinals Will Beat the Red Sox
- The Cardinals have won five of their last six games as underdogs after playing the previous day.
- The Red Sox have lost nine of their last 10 games against National League opponents that held a winning record.
- The Cardinals have covered the run line in nine of their last 10 games as underdogs.
- The Red Sox have failed to cover the run line in eight of their last nine home games against NL Central opponents following a home win.
Red Sox vs Cardinals Prediction
The Cardinals lost on Friday, but this is a great bounce-back spot for them. Pallante looked really good against the Twins, and outside of the longball, he was nearly perfect. The Red Sox’s offense was good on Friday, but they won’t be as good against Pallante. We all know the Cardinals’ offense can score, and they are going to tee off against Richard Fitts. The Red Sox jumped out on Friday; in this game, it will be the Cardinals that do the same. Back the Cardinals on the money line.