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Red Sox vs Royals Prediction 8-6-25 MLB Picks

Kansas City Royals (56-58) vs. Boston Red Sox (64-51)
August 6, 2025 7:10 pm EDT
The Line: Boston Red Sox -150 / Kansas City Royals 122; Over/Under: 9
(Get latest betting odds)

The Kansas City Royals and Boston Red Sox meet Wednesday in MLB action at Fenway Park. Here’s a Red Sox vs Royals Prediction. This article will include a Red Sox vs Royals Pick.

Kansas City Royals Betting Preview

The Kansas City Royals are 56-58 on the year and play the Twins, Nationals, and White Sox next. The Kansas City Royals are batting .243 on the season, have a .300 OBP, and a .385 slugging percentage. The Kansas City Royals pitching staff has a 3.60 ERA and a 1.23 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 128 hits and 63 RBI, while Maikel Garcia and Vinnie Pasquantino have combined for 238 hits and 117 RBI.

Michael Wacha gets the ball for the Kansas City Royals, and he is 5-9 with a 3.38 ERA and 95 strikeouts this season. Wacha is 2-1 with a 2.14 ERA and 21 strikeouts in his career against the Boston Red Sox.

Boston Red Sox Betting Preview

The Boston Red Sox are 64-51 on the year and play the Padres, Astros, and Marlins next. The Boston Red Sox are batting .254 on the season, have a .324 OBP, and a .431 slugging percentage. The Boston Red Sox pitching staff has a 3.69 ERA and a 1.29 WHIP. Jarren Duran leads the Boston Red Sox with 120 hits and 64 RBI while Trevor Story and Ceddanne Rafaela have combined for 211 hits and 123 RBI.

Dustin May gets the ball for the Boston Red Sox, and he is 6-7 with a 4.85 ERA and 97 strikeouts this season. This will be May’s second career game against the Kansas City Royals.

Why the Boston Red Sox will win

  • The Red Sox have won each of their last 14 home games after playing the previous day.
  • The Royals have lost each of their last eight Wednesday night games against American League opponents that held a winning record.
  • The Red Sox have covered the run line in each of their last seven games.
  • The Royals have failed to cover the run line in eight of their last 10 night games against AL East opponents.
  • The Royals have trailed after 3 innings in each of their last four games against American League opponents that held a winning record.
  • The Royals have lost the first inning in three of their last four night games against American League opponents.
  • The Red Sox have led after 5 innings in five of their last six games as favorites.

Why the Kansas City Royals will win

  • The Royals have won five of their last six games as road underdogs following a loss.
  • The Royals have covered the run line in each of their last 11 Wednesday road games.
  • The Red Sox have failed to cover the run line in seven of their last nine night games against American League opponents that held a losing record.
  • The Royals have led after 5 innings in each of their last six Wednesday road games.
  • The Royals have led after 3 innings in each of their last six Wednesday road games.

Boston Red Sox Player Prop Facts

  • Jarren Duran has hit a home run in three of the Red Sox’s last four games against AL Central opponents.
  • Dustin May has recorded four or more strikeouts in 13 of his last 14 home appearances against opponents that held a losing record.
  • Trevor Story has recorded at least one hit in each of his last 11 home appearances against AL Central opponents.
  • Dustin May has recorded a win in three of his last four home appearances.
  • Jarren Duran has recorded at least one Double in each of the Red Sox’s last seven night games against AL opponents that held a losing record.

Kansas City Royals Player Prop Facts

  • Salvador Perez has hit at least one home run in six of the Royals’ last 10 road games.
  • Michael Wacha has recorded five or more strikeouts in each of his last eight Wednesday appearances against AL teams that held a winning record.
  • Maikel Garcia has recorded at least one hit in each of the Royals’ last six night games.
  • Michael Wacha has recorded a win in four of his last five appearances at Fenway Park against opponents that held a winning record.
  • Bobby Witt Jr. ranks 6th in the league in Hits (128) this season.

Red Sox vs Royals Prediction

The Royals are worth a look with Wacha on the mound, as he’s easily been a top-30 starter with a 3.38 ERA and 1.16 WHIP. I’m just not going to step in front of the Red Sox, a team that’s been in fire this week. May has also pitched his best at home through 57 innings, where he has a 3.00 ERA and .219 allowed batting average. The Yankees are slumping, the Red Sox are hot. There’s energy in Boston right now. I’m riding the hot hand with the Red Sox.

Randy Chambers's Free Pick: Boston Red Sox -150

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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