Red Sox vs Tigers Prediction 5/6/26 MLB Picks Today

In this article, we will formulate a Red Sox vs Tigers Prediction for this MLB matchup on Wednesday, May 6^th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Detroit Tigers Preview

The Detroit Tigers have a 18-19 record this season and are sitting in the first place of the AL Central. They have a 12-5 home record and are coming off a 3-10 loss at home against the Red Sox. They will face the Royals and the Mets next.

The Tigers have a .246 batting average this season, .327 OBP and .398 Slugging percentage. Detroit’s pitching staff has a 3.93 ERA and 1.32 WHIP. Kevin McGonigle is the team’s best hitter with a .308 batting average. Dillon Dingler leads the team in RBI with 26, and Kerry Carpenter adds a team‑high 6 home runs.

Jack Flaherty (R) is the projected starting pitcher for the Tigers, and he has a 0-2 record, 5.90 ERA and 1.79 WHIP.

Boston Red Sox Preview

The Boston Red Sox have a 15-21 record this season and are sitting in the fifth place of the AL East. They have a 9-11 away record and are coming off a 10-3 win on the road against the Tigers. They will face the Rays and the Phillies next.

The Red Sox have a .240 batting average this season, .318 OBP and .361 Slugging percentage. Boston’s pitching staff has a 4.11 ERA and 1.31 WHIP. Wilyer Abreu is the team’s best hitter with a .311 batting average. Willson Contreras leads the team in RBI with 22, also adding a team‑high 8 home runs.

Sonny Gray (R) is the projected starting pitcher for the Red Sox, and he has a 2-1 record, 4.30 ERA and 1.30 WHIP.

Boston Red Sox @ Detroit Tigers Betting Trends: May 6, 2026

• Probable Starting Pitcher: Jack Flaherty      Record this season: 0-2      ERA: 5.90
• Home Record: 0-0
• Last 5 against Red Sox: 1-0

Why the Detroit Tigers will win

• The Tigers have won eight of their last 10 home games against AL East opponents that held a losing record.
• The Red Sox have lost seven of their last eight games as underdogs against the Tigers following a win.
• The Red Sox have failed to cover the run line each of their last six Wednesday games against teams that held a losing record.
• The Tigers have covered the run line in four of their last five games against AL East opponents following a loss.

• Probable Starting Pitcher: Sonny Gray      Record this season: 2-1      ERA: 4.30
• Road Record: 0-1
• Last 5 against Tigers: 2-1

Why the Boston Red Sox will win

• The Tigers have lost five of their last six games as home favorites against AL East opponents.
• The underdogs have won three of the Red Sox’s last four games.
• The Red Sox have covered the run line in each of their last eight games as road underdogs against AL Central opponents.
• The Tigers have failed to cover the run line in each of their last 11 Wednesday games as favorites against American League opponents.
• The Red Sox have led after 5 innings in four of their last five games as road underdogs against AL Central opponents.
• The Red Sox have led after 3 innings in four of their last five games against AL Central opponents that held a losing record.

Total Runs Facts

• Each of the last five games between the Red Sox and Tigers at Comerica Park have gone OVER the total runs line.
• Each of the Red Sox’s last four games against AL Central opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Red Sox’s last 12 Wednesday games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the last eight night games between the Red Sox and Tigers at Comerica Park.

Detroit Tigers Player Prop Facts

• Spencer Torkelson has hit a home run in six of the Tigers’ last 10 games as favorites.
• Jack Flaherty has recorded six or more strikeouts in each of his five previous appearances with the Tigers as favorites against AL East opponents.
• Javier Baez has recorded at least one hit in each of his last nine appearances against AL East opponents.

Boston Red Sox Player Prop Facts

• Trevor Story has hit a home run in three of the Red Sox’s last four road games against AL Central opponents that held a losing record.
• Sonny Gray has recorded a win in each of his last five road appearances against AL opponents that held a losing record.
• Sonny Gray has recorded five or more strikeouts in each of his last nine Wednesday appearances against teams that held a losing record.
• Trevor Story has recorded at least one hit in each of his last nine road appearances after playing the previous day.

Matchup/League Facts

• The Tigers rank 3rd in the league for doubles this season (66).
• The Tigers rank T27th in the league for steals this season (15).
• The Red Sox rank T27th in the league for home runs this season (27).
• The Red Sox rank 27th in the league for slugging percentage this season (.361).

Red Sox vs Tigers Prediction

The Red Sox are 5-2 in their last 7 meetings against the Tigers and have won their last two visits in Detroit.

In this Red Sox vs Tigers Prediction, the Tigers are coming as -120 home favorites. Boston won both games in this series and will face Jack Flaherty today, who has been bad this season and in terrible form, having 10 earned runs across his last two starts. Sonny Gray has just one earned run in two of his last three starts and the Red Sox have a better bullpen to back him up, so I expect them to keep rolling today and I’m loving the plus money that come with them. Take the Red Sox on the moneyline on the road.