Reds vs Athletics Prediction 9/13/25 MLB Picks Today

In this article, we will formulate a Reds vs Athletics Prediction for this MLB game on Saturday, September 13^th at the Sutter Health Park the second game of this series, with the Athletics having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Athletics Preview

The Athletics have a 68-80 record this season and are sitting on the last place of the AL West. The Athletics have a 31-42 home record and are 73-69 in over/under. They are coming off a 3-0 home victory over the Reds, and have back-to-back wins. Under is 7-2 in their last 9 games and are playing the Red Sox and the Pirates next.

The Athletics have a .254 batting average this season, .320 OBP and .434 Slugging percentage. Athletics’ pitching staff has a 4.78 ERA and 1.36 WHIP. Brent Rooker leads the Athletics with 155 hits, while Jacob Wilson is the team’s best hitter with a .317 batting average. Tyler Soderstrom adds a team-high 88 RBI, while Shea Langeliers adds a team-high 30 home runs.

Luis Severino (R) is the projected starter for the Athletics, and he has a 6-11 record, 4.67 ERA, and 1.31 WHIP.

Cincinnati Reds Preview

The Cincinnati Reds have a 74-73 record this season and are sitting in the third place of the NL Central. The Reds have a 34-39 road record and are 54-85 in over/under. They are coming off a 0-3 road defeat by the A’s, which ended their two-game winning streak. Under is 5-0-1 in their last 6 games and are playing the Cardinals and the Cubs next.

The Reds have a .246 batting average this season, .316 OBP and .390 slugging percentage. Cincinnati’s pitching staff has a 3.91 ERA and 1.24 WHIP.  Elly De La Cruz leads the Reds with 154 hits, and in RBI, with 82, adding a team-high 19 home runs. He is also the team’s best hitter with a .266 batting average.

Hunter Greene (R) is the projected starting pitcher for the Reds, and he has a 6-4 record, 2.59 ERA and 0.93 WHIP.

Cincinnati Reds @ Athletics Betting Trends: September 13, 2025

• Probable Starting Pitcher: Luis Severino      Record this season: 6-11      ERA: 4.67
• Home Record: 1-9
• Last 5 against Reds: 1-0

Why the Athletics will win

• The underdogs have won eight of the Athletics’ last 10 games.
• The Reds have lost each of their last six night games against teams that held a losing record.
• The Athletics have covered the run line in each of their last six games against the Reds.
• The Reds have failed to cover the run line in seven of their last eight games as favorites following a loss.
• The Reds have lost the first inning in each of their last four road games against opponents that held a losing record.
• The Reds have trailed after 3 innings in each of their last four road games against opponents that held a losing record.
• The Reds have trailed after 5 innings in each of their last five night games against opponents that held a losing record.

• Probable Starting Pitcher: Hunter Greene      Record this season: 6-4      ERA: 2.59
• Road Record: 2-3
• Last 5 against Athletics: 0-0

Why the Cincinnati Reds will win

• The Athletics have lost each of their last eight games as underdogs against National League opponents following a win.
• The Reds have won each of their last six games as favorites against American League opponents.
• The Athletics have failed to cover the run line in each of their last eight games as underdogs against National League opponents following a win.
• The Reds have covered the run line in five of their last six road games against American League opponents after playing the previous day.
• The Athletics have trailed after 3 innings in each of their last five games as home underdogs against NL Central opponents.
• The Reds have led after 5 innings in each of their last four games as favorites against American League opponents.

Total Runs Facts

• Seven of the Reds’ last eight road games have gone UNDER the total runs line.
• Seven of the Athletics’ last eight night games against National League opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last seven games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Reds’ last eight Saturday night games against AL West opponents.

Athletics Player Prop Facts

• Lawrence Butler has hit at least one home run in each of the Athletics’ last four games against the Reds.
• Brent Rooker has recorded at least one Double in each of the Athletics’ last three games as underdogs against NL opponents.
• Luis Severino has recorded a win in each of his last four appearances with the Athletics as underdogs.
• Luis Severino has recorded six or more strikeouts in each of his last three appearances against opponents that held a winning record.
• Shea Langeliers has recorded at least one hit in each of his last nine appearances against NL opponents.
• Jacob Wilson ranks 2nd amongst qualified players for Batting Average (.317) this season.

Cincinnati Reds Player Prop Facts

• Hunter Greene has recorded eight or more strikeouts in each of his three previous appearances with the Reds as favorites against AL West opponents.
• Miguel Andujar has recorded at least one hit in each of his last 13 appearances with his team as a favorite against AL West opponents.
• Will Benson has hit a home run in each of the Reds’ last two games as favorites against the Athletics.
• Hunter Greene is one of only four pitchers to record 90+ Strikeouts and 20 or less Walks this season.

Matchup/League Facts

• The Athletics rank 2nd in the league for doubles this season (271).
• The Athletics rank 28th in the league for steals this season (72).
• The Reds rank 6th in the league for opponent batting average this season (.235).
• The Reds rank 7th in the league for hits allowed this season (1154).

Reds vs Athletics Prediction

The Athletics are 4-1 in their last 5 head-to-head meetings against the Reds, but the Reds are 3-2 in their last 5 road meetings against the A’s. Over is 3-2 in their last 5 meetings.

In this Reds vs Athletics Prediction, the Reds are coming as -115 road favorites. I don’t trust Severino at all for the A’s, as he has been bad at home, with a 6.34 home ERA. On the flip side, Greene has been elite for the Reds, but is slightly weaker on the road, with a 3.89 road ERA. Greene is coming off back-to-back quality starts with just two earned runs in total, while Severino has 3 earned runs in two of his last three starts. the Reds have a better bullpen, and are better than the A’s against right-handed pitching, so I like them in a bounce-back spot on the road today as small favorites. Take the Cincinnati Reds on the moneyline in this one.