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Reds vs Cubs Prediction 7/10/26 MLB Picks Today

Chicago Cubs (52-41) vs. Cincinnati Reds (42-50)
July 10, 2026 7:10 pm EDT
The Line: Cincinnati Reds -102 / Chicago Cubs -118; Over/Under: 9.5
(Get latest betting odds)

In this article we will formulate a Reds vs Cubs prediction for this MLB game on Friday, July 10th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 42-50 this season after they lost two out of three against the Phillies by scores of 1-4, 11-5, and 0-1. In game three, Cincinnati pitched a very strong game, but they allowed a run in the eighth inning for the loss. The Reds recorded three hits in the game and they were led by Bleday, who went 1-4. Singer allowed four hits and one earned run over 7.1 innings for the loss, while Antone pitched a scoreless inning in relief. Prior to that series, Cincinnati lost two out of three against the Orioles and three out of four against the Brewers. 

This season, Cincinnati has a 4.53 ERA with a 1.45 WHIP and a .248 opponent batting average, while they have scored 384 runs with a .227 batting average and a .309 on base percentage. Sal Stewart has led the Reds with 19 home runs and 64 RBIs, while Elly De La Cruz has added 14 home runs and 43 RBIs. The projected starting pitcher for Cincinnati is Hunter Greene, who is 0-1 with a 21.60 ERA and a 3.30 WHIP over 3.1 innings pitched this season. 

Chicago Cubs Betting Preview

The Chicago Cubs are 52-41 this year after they won two out of three against the Orioles by scores of 5-2, 9-7, and 2-3. In game three, Chicago led 2-1 in the eighth inning, but they allowed two runs in the bottom of the eighth for the loss. The Cubs recorded nine hits in the game and they were led by Suzuki, who went 3-4 with one home run and two RBIs. Peterson allowed two hits and one earned run over 5.0 innings, while Ferguson picked up the loss in relief. Prior to that series, Chicago lost two out of three against the Cardinals, but did win all three against the Padres before that. 

This season, Chicago has a 4.35 ERA with a 1.27 WHIP and a .244 opponent batting average, while they have scored 471 runs with a .244 batting average and a .337 on base percentage. Dansby Swanson has led the Cubs with 16 home runs and 58 RBIs, while Ian Happ has added 17 home runs and 41 RBIs. The projected starting pitcher for Chicago is Shota Imanaga, who is 5-7 with a 4.28 ERA and a 1.10 WHIP over 103.0 innings pitched this year. 

Why the Cincinnati Reds will win

  • The home team has won each of the last nine games between the Cubs and Reds.
  • The Cubs have lost six of their last eight games as favorites against NL Central opponents.
  • The Reds have covered the run line in each of their last six games as home underdogs against the Cubs following a home loss.
  • The Cubs have failed to cover the run line in 13 of their last 16 games as favorites against NL Central opponents.
  • The Reds have won the first inning in each of their last five games as underdogs against the Cubs at Great American Ball Park.
  • The Cubs have trailed after 5 innings in six of their last seven games at Great American Ball Park.
  • The Cubs have trailed after 3 innings in five of their last six games at Great American Ball Park against opponents that held a losing record.

Why the Chicago Cubs will win

  • The Cubs have won each of their last eight games against NL Central opponents that held a losing record.
  • The Reds have lost nine of their last 10 night games after playing the previous day.
  • The Cubs have covered the run line each of their last six games against NL Central opponents that held a losing record.
  • The Reds have failed to cover the run line in four of their last five games against NL Central opponents.
  • The Cubs have won the first inning in four of their last five games against NL Central opponents that held a losing record.
  • The Cubs have led after 5 innings in seven of their last eight night games against NL Central opponents that held a losing record.
  • The Reds have trailed after 3 innings in four of their last five games as home underdogs against NL Central opponents.

Total Runs Facts

  • Each of the Reds’ last six night games as underdogs have gone UNDER the total runs line.
  • Four of the Cubs’ last five games against National League opponents have gone OVER the total runs line.
  • There has been no run scored during the first inning in each of the Reds’ last seven home games against National League opponents.
  • There has been no run scored during the first inning in 10 of the Cubs’ last 11 road games.

Cincinnati Reds Player Prop Facts

  • Eugenio Suarez has hit at least one home run in three of his last four home appearances against the Cubs.
  • Hunter Greene has recorded seven or more strikeouts in each of his last five home appearances.
  • Elly De La Cruz has recorded at least one hit in each of his last 10 appearances with the Reds as home underdogs against NL Central opponents.
  • Hunter Greene has recorded a win in four of his five previous home appearances against the Cubs.

Chicago Cubs Player Prop Facts

  • Pete Crow-Armstrong has hit at least one home run in four of the Cubs’ last five night games against NL Central opponents that held a losing record.
  • Shota Imanaga has recorded seven or more strikeouts in three of his four previous appearances against the Reds.
  • Pete Crow-Armstrong has recorded at least one hit in each of the Cubs’ last 18 games as favorites.
  • Pete Crow-Armstrong is one of only two players to record 10+ Home Runs and 4+ Triples this season.

Matchup/League Facts

  • The Reds rank 29th in the league for hits this season (698).
  • The Reds rank 29th in the league for batting average this season (.227).
  • The Cubs rank 1st in the league for walks this season (406).
  • The Cubs rank 29th in the league for home runs allowed this season (142).

Reds vs Cubs Prediction 

Chicago comes into this matchup after winning three of their last four games and they have scored 5+ runs in all three of those wins. The Cubs are 25-22 on the road this year, while the Reds are 21-26 at home. Cincinnati has alternated wins and losses over their last five games and they have scored one run or fewer in two of their last three. The Reds are starting Greene, who allowed seven hits and eight earned runs over 3.1 innings in his first start, while Imanaga has allowed two earned runs or fewer in four of his last five starts. Take the Cubs here. 

David Racey's Free Pick: Cubs ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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