Reds vs Guardians Prediction 7/29/26 MLB Picks Today

The Cleveland Guardians and Cincinnati Reds meet Wednesday in MLB action at Great American Ball Park. Here’s a Reds vs Guardians Prediction. This article will include a Reds vs Guardians Pick.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 55-54 on the year and play the Diamondbacks and Mets next. The Cleveland Guardians are batting .230 on the season, have a .309 OBP, and have a .368 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.75 ERA and a 1.26 WHIP. Brayan Rocchio leads the Cleveland Guardians with 98 hits and 50 RBI, while Chase DeLauter and Steven Kwan have combined for 178 hits and 69 RBI.

Joey Cantillo gets the ball for the Cleveland Guardians, and he is 8-6 with a 4.02 ERA and 116 strikeouts this season. Cantillo is 0-0 with a 6.75 ERA and 5 strikeouts in his career against the Cincinnati Reds.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 50-56 on the year and play the Athletics and Pirates next. The Cincinnati Reds are batting .230 on the season, have a .308 OBP, and have a .397 slugging percentage. The Cincinnati Reds’ pitching staff has a 4.46 ERA and a 1.41 WHIP. Sal Stewart leads the Cincinnati Reds with 102 hits and 79 RBI, while Elly De La Cruz and Spencer Steer have combined for 177 hits and 87 RBI.

Brady Singer gets the ball for the Cincinnati Reds, and he is 5-9 with a 4.53 ERA and 88 strikeouts this season. Singer is 3-4 with a 5.18 ERA and 65 strikeouts in his career against the Cleveland Guardians.

Why the Cincinnati Reds will win

• The underdogs have won each of the Reds’ last seven games.
• The Guardians have lost four of their last five games as favorites.
• The underdogs have covered the run line in each of the Reds’ last seven games.
• The Guardians have failed to cover the run line in 26 of their last 31 games as favorites.
• The Guardians have trailed after 3 innings in each of their last three night games against NL Central opponents.
• The Guardians have trailed after 5 innings in each of their last six night games against NL Central opponents.

Why the Cleveland Guardians will win

• The Reds have lost each of their last seven home games following a win.
• The Guardians have won five of their last six road games against National League opponents.
• The Guardians have covered the run line in seven of their last eight games as road favorites against National League opponents following a road loss.
• The Reds have failed to cover the run line in each of their last five night games against American League opponents following a win.
• The Reds have trailed after 5 innings in each of their last seven Wednesday games against American League opponents that held a winning record.
• The Reds have trailed after 3 innings in three of their last four games.

Total Runs Facts

• Each of the Guardians’ last six games as road favorites have gone UNDER the total runs line.
• Eleven of the Reds’ last 12 night games as underdogs have gone UNDER the total runs line.
• There has been no run scored during the first inning in each of Brady Singer’s last six home appearances as a starter against the Guardians.
• There has been at least one run scored in the first inning in four of the Guardians’ last five games as road favorites against National League opponents.

Cincinnati Reds Player Prop Facts

• Brady Singer has recorded five or more strikeouts in each of his last nine appearances.
• Sal Stewart has recorded at least one hit in each of the Reds’ last nine Wednesday games.
• Brady Singer has recorded a win in each of his last three appearances in night games against AL Central teams that held a winning record.
• Nathaniel Lowe has hit at least one home run in three of his last four appearances with the Reds as home underdogs against AL opponents.
• Elly De La Cruz is one of only eight players to record 10+ Home Runs and 4+ Triples this season.

Cleveland Guardians Player Prop Facts

• Angel Martinez has hit a home run in each of his last two appearances with the Guardians as favorites against the Reds.
• Joey Cantillo has recorded seven or more strikeouts in four of his last five road appearances.
• Steven Kwan has recorded at least one hit in each of his last 12 Wednesday appearances with the Guardians as favorites.
• Joey Cantillo has recorded a win in three of his last four appearances in night games against teams that held a losing record.
• Jose Ramirez ranks T4th in the league in Steals (26) this season.

Matchup/League Facts

• The Reds rank 30th in the league for hits this season (815).
• The Reds rank 30th in the league for hits this season (815).
• The Guardians rank 30th in the league for slugging percentage this season (.368).
• The Guardians rank 30th in the league for slugging percentage this season (.368).

Reds vs Guardians Prediction

Cantillo has been hittable with a 4.02 ERA and 1.46 WHIP on the season, and he’s allowed 30 hits and 12 earned runs in his last 23.2 innings. In 60 innings on the road, Cantillo has a 4.20 ERA and a .278 batting average allowed. Singer is enjoying July, where he’s allowed 17 hits and 8 earned runs in 26 innings. That should continue at home, where Singer has a 2.98 ERA and .228 allowed batting average. It’s a bit strange we’re getting the Reds at home with the more favorable price, but I’ll take it.