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Reds vs Pirates Prediction 4/12/25 MLB Picks Today

Pittsburgh Pirates (5-9) vs. Cincinnati Reds (6-8)
April 12, 2025 6:40 pm EDT
The Line: Cincinnati Reds -130 / Pittsburgh Pirates 110; Over/Under: 8.5
(Get latest betting odds)

In this article, we will formulate a Reds vs Pirates prediction for this MLB game on Saturday, April 12, at  Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates (5-9, 2-6 Away) lost the opening three series of the season to the Marlins, Rays, and Yankees, but beat the Cardinals 2-1. Pittsburgh lost the first game of the current series 5-3 to the Reds after allowing five runs in the opening three innings. Adam Frazier led the offense with two RBI, while Bailey Falter took the loss after allowing five runs (three earned) on three hits with four strikeouts and five walks in 5.0 innings.

This season, the Pirates average 3.43 runs per game (26th in the MLB) on a .194/.287/.299 slash line. Regarding pitching, the Pirates’ staff has a 4.31 ERA (20th) and 1.33 WHIP (19th). Bryan Reynolds leads the Pirates with a .200 batting average, two home runs, and six RBI this season.

The projected starting pitcher for the Pirates is Andrew Heaney, who has a 0-0 record in two starts this year with a 1.50 ERA and 0.92 WHIP in 12.0 innings.

Cincinnati Reds Betting Preview

The Cincinnati Reds (6-8, 3-4 Home) lost the series to the Giants, Rangers, and Milwaukee before recording the first series win of the season as they defeated San Francisco 2-1. Jeimer Candelario contributed two RBI in the latest 5-3 victory over the Pirates, while Brady Singer improved to 3-0 after allowing three runs on two hits with three strikeouts and three walks over 5.0 innings of work.

This year, the Reds average 3.79 runs per game (19th in the MLB) on a .203/.270/.325 triple-slash. When it comes to pitching, the Reds’ staff has a 3.14 ERA (6th) and 0.97 WHIP (1st). Elly De La Cruz leads the Reds with a .236 batting average, two home runs, and 12 RBI this season.

Andrew Abbott will take the mound for the Reds on Saturday. The 25-year-old left-hander will be activated from the 15-day injured list and make his season debut against the Pirates.

Total Runs Facts

  • Five of the Reds’ last six games as favorites have gone UNDER the total runs line.
  • Five of the Pirates’ last six road games after playing the previous day have gone UNDER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last four night games between the Pirates and Reds.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Pirates’ last three night games at Great American Ball Park.

Matchup/League Facts

  • The Reds rank 2nd in the league for walks allowed this season (33).
  • The Reds rank T28th in the league for triples this season (0).
  • The Pirates rank T2nd in the league for triples this season (3).
  • The Pirates rank T2nd in the league for home runs allowed this season (9).

Reds vs Pirates Prediction

The Pirates won six of the previous ten games, but the Reds won three of the last four. Four of the last five H2Hs produced under 8.5 runs, and I am going with Under here because of the pitching matchup. Namely, both teams are bad against southpaws this season; the Reds have a .142 BA in 113 at-bats, while the Pirates have a .196 BA in 102 at-bats. Heaney was excellent in his first two starts and allowed just a run in each, so I expect him to continue with dominant displays on Saturday. Back the Under.


Oliver Zivic

Professional journalist and expert bettor with 20+ years of experience. I cover Football (soccer), NFL, NBA, NHL, MLB, CFB, and CBB.

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