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Reds vs Rockies Prediction 4/29/26 MLB Picks Today

Colorado Rockies (13-17) vs. Cincinnati Reds (19-10)
April 29, 2026 6:40 pm EDT
The Line: Cincinnati Reds -156 / Colorado Rockies 129; Over/Under: 9.5
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In this article we will formulate a Reds vs Rockies prediction for this MLB game on Wednesday, April 29th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 19-10 this year after they won game one by a score of 7-2 on Tuesday night. Cincinnati scored three runs in the first inning and never looked back in the victory. The Reds recorded 11 hits and they committed one error in the game, while they were led by De La Cruz, who went 3-4 with one home run and four RBIs. Burns allowed seven hits and two earned runs over 6.0 innings for the win, while Santillan picked up a hold. Prior to this series, Cincinnati won two out of three against the Tigers and two out of three against the Rays. 

This season, Cincinnati has a 3.71 ERA with a 1.40 WHIP and a .241 opponent batting average, while they have scored 125 runs with a .218 batting average and a .309 on base percentage. Sal Stewart has led the Reds with nine home runs and 29 RBIs, while Elly De La Cruz has added 10 home runs and 24 RBIs. The projected starting pitcher for Cincinnati is Brandon Williamson, who is 2-2 with a 5.40 ERA and a 1.52 WHIP over 25.0 innings pitched this year. 

Colorado Rockies Betting Preview

The Colorado Rockies are 13-17 this season after they lost game one by a score of 7-2 last night. Colorado cut the deficit to 4-2 in the fifth inning, but couldn’t get any closer in the loss. The Rockies recorded 11 hits in the game and they were led by Julien, who went 3-4 with one home run and two RBIs. Freeland allowed five hits and four earned runs over 5.0 innings for the loss, while Gordon allowed three earned runs in relief. Prior to this series, Colorado swept the Mets in three games, but lost two out of three against the Padres before that. 

This season, Colorado has a 4.19 ERA with a 1.37 WHIP and a .263 opponent batting average, while they have scored 120 runs with a .249 batting average and a .316 on base percentage. Mickey Moniak has led the Rockies with eight home runs and 15 RBIs, while TJ Rumfield has added three home runs and 16 RBIs. The projected starting pitcher for Colorado is Tomoyuki Sugano, who is 2-1 with a 3.42 ERA and a 1.14 WHIP over 26.1 innings pitched this season. 

Why the Cincinnati Reds will win

  • The Rockies have lost each of their last 11 games against National League opponents following a road loss.
  • The Reds have won 15 of their last 17 games against the Rockies.
  • The Reds have covered the run line in seven of their last eight night games following a win.
  • The Rockies have failed to cover the run line each of their last four road games against teams that held a winning record.
  • The Rockies have trailed after 3 innings in each of their last eight Wednesday road games.
  • The Reds have won the first inning in four of their last five games against the Rockies.
  • The Rockies have trailed after 5 innings in each of their last six road games against opponents that held a winning record.

Why the Colorado Rockies will win

  • The Reds have lost five of their last six games as home favorites against NL West opponents following a win.
  • The Rockies have won four of their last five games as road underdogs.
  • The Rockies have covered the run line in each of their last five games following a loss.
  • The Reds have failed to cover the run line in each of their last six Wednesday night games as favorites against NL West opponents.

Total Runs Facts

  • Eight of the Reds’ last nine home games after playing the previous day have gone OVER the total runs line.
  • Five of the Rockies’ last six games as underdogs against the Reds have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Reds’ last 11 games as home favorites against National League opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of Tomoyuki Sugano’s last 11 appearances as a starter.

Cincinnati Reds Player Prop Facts

  • Spencer Steer has hit a home run in four of the Reds’ last five games as favorites.
  • Elly De La Cruz has recorded at least one hit in each of his 16 previous appearances against the Rockies.
  • Elly De La Cruz ranks T4th in the league in Home Runs (10) this season.

Colorado Rockies Player Prop Facts

  • Kris Bryant has recorded at least one hit in each of his last 10 appearances in night games against NL Central teams that held a winning record.
  • Edouard Julien has hit a home run in two of the Rockies’ last three road games against opponents that held a winning record.

Matchup/League Facts

  • The Reds rank 30th in the league for hits this season (209).
  • The Reds rank 30th in the league for batting average this season (.218).
  • The Rockies rank 28th in the league for strikeouts against this season (284).
  • The Rockies are one of only three teams in the league to rank top 10 in both steals and batting average this season.

Reds vs Rockies Prediction 

Colorado had their three game winning streak snapped on Tuesday night and they have scored three runs or fewer in three straight. The Rockies are 6-11 on the road this year, while the Reds are 9-7 at home. Cincinnati has won three of their last four games and they have scored 7+ runs in all three wins. The Reds are starting Williamson, who has allowed nine earned runs and 13 hits in his last 13.2 innings, while Sugano has allowed two earned runs or fewer in four of his last five outings. Take the Rockies to get the win here. 

David Racey's Free Pick: Rockies ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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