Royals vs Mariners Prediction 9/16/25 MLB Picks Today

The Seattle Mariners and Kansas City Royals meet Tuesday in MLB action at Kauffman Stadium. Here’s a Royals vs Mariners Prediction. This article will include a Royals vs Mariners Pick.

Seattle Mariners Betting Preview

The Seattle Mariners are 82-68 on the year and play the Astros, Rockies, and Dodgers next. The Seattle Mariners are batting .244 on the season, have a .320 OBP, and a .416 slugging percentage. The Seattle Mariners pitching staff has a 3.91 ERA and a 1.24 WHIP. Julio Rodriguez leads the Seattle Mariners with 165 hits and 91 RBI, while JP Crawford and Randy Arozarena have combined for 279 hits and 125 RBI.

Logan Gilbert gets the ball for the Seattle Mariners, and he is 4-6 with a 3.54 ERA and 159 strikeouts this season. Gilbert is 2-1 with a 4.66 ERA and 39 strikeouts in his career against the Kansas City Royals.

Kansas City Royals Betting Preview

The Kansas City Royals are 75-75 on the year and play the Blue Jays, Angels, and Athletics next. The Kansas City Royals are batting .244 on the season, have a .305 OBP, and a .391 slugging percentage. The Kansas City Royals pitching staff has a 3.73 ERA and a 1.25 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 166 hits and 79 RBI while Maikel Garcia and Vinnie Pasquantino have combined for 312 hits and 174 RBI.

Michael Wacha gets the ball for the Kansas City Royals, and he is 9-11 with a 3.45 ERA and 117 strikeouts this season. Wacha is 2-4 with a 6.00 ERA and 33 strikeouts in his career against the Seattle Mariners.

Seattle Mariners @ Kansas City Royals Betting Trends: September 16, 2025

• Probable Starting Pitcher: Michael Wacha      Record this season: 9-11      ERA: 3.45
• Home Record: 5-5
• Last 5 against Mariners: 2-1

Why the Kansas City Royals will win

• The Mariners have lost seven of their last eight games as road favorites against American League opponents.
• The home team has won each of the Mariners’ last seven games.
• The Mariners have failed to cover the run line in each of their last seven road games against American League opponents following a win.
• The underdogs have covered the run line in each of the Royals’ last six games at Kauffman Stadium.
• The Royals have won the first inning in each of their last three night games.
• The Mariners have trailed after 3 innings in each of their last four road games against American League opponents.
• The Royals have led after 5 innings in four of their last five games against AL West opponents.

• Probable Starting Pitcher: Logan Gilbert      Record this season: 4-6      ERA: 3.54
• Road Record: 1-4
• Last 5 against Royals: 1-1

Why the Seattle Mariners will win

• The Mariners have won each of their last nine games.
• The Royals have lost nine of their last 10 home games against American League opponents that held a winning record.
• The Royals have failed to cover the run line in each of their last four night games against AL West opponents.
• The road team has covered the run line in four of the last five games between the Mariners and Royals.
• The Royals have lost the first inning in four of their last five games against American League opponents.
• The Mariners have led after 3 innings in four of their last five games at Kauffman Stadium.
• The Royals have trailed after 5 innings in five of their last six home games against American League opponents that held a winning record.

Total Runs Facts

• Each of the last nine games between the Mariners and Royals at Kauffman Stadium have gone OVER the total runs line.
• Each of the Mariners’ last four games as road favorites have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Royals’ last nine games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Mariners’ last five road games.

Kansas City Royals Player Prop Facts

• Salvador Perez has hit at least one home run in each of the Royals’ last two games.
• Michael Wacha has recorded four or more strikeouts in each of his last six appearances with the Royals as home underdogs.
• Vinnie Pasquantino has recorded at least one hit in each of his last 10 home appearances against AL West opponents that held a winning record.
• Michael Wacha has recorded a win in five of his last six appearances in night games.
• Bobby Witt Jr. ranks 3rd in the league in Hits (166) this season.

Seattle Mariners Player Prop Facts

• Randy Arozarena has hit at least one home run in three of the Mariners’ last four games against the Royals.
• Jorge Polanco has recorded at least one hit in each of the Mariners’ last 12 games.
• Jorge Polanco has recorded at least one Double in each of the Mariners’ last seven games.
• Cal Raleigh ranks 1st in the league in Home Runs (54) this season.

Matchup/League Facts

• The Royals rank 1st in the league for strikeouts against this season (1015).
• The Royals rank 29th in the league for walks this season (397).
• The Mariners rank 29th in the league for doubles this season (215).
• The Mariners rank T29th in the league for triples this season (8).

Royals vs Mariners Prediction

The Royals can’t string together wins all of a sudden and Wacha will pitch for the first time in a week after dealing with a concussion. Not excited about the Royals. The Mariners have won 9 straight games and all of a sudden are in the driver’s seat for the AL West. Gilbert has had his issues on the road this season, but he’s been sharp overall. Gilbert is also holding current Royals to a .235 batting average and 19 strikeouts in 81 at bats. I’m not stepping in front of the Mariners with how they’re racking up the wins. Hottest team in the league right now. I’ll ride it until it runs cold. Give me the M’s.