Royals vs Twins Prediction 9/6/25 MLB Picks Today

The Minnesota Twins and Kansas City Royals meet Saturday in MLB action at Kauffman Stadium. Here’s a Royals vs Twins Prediction. This article will include a Royals vs Twins Pick.

Minnesota Twins Betting Preview

The Minnesota Twins are 62-79 on the year and play the Angels, Diamondbacks, and Yankees next. The Minnesota Twins are batting .239 on the season, have a .312 OBP, and a .397 slugging percentage. The Minnesota Twins pitching staff has a 4.53 ERA and a 1.32 WHIP. Trevor Larnach leads the Minnesota Twins with 116 hits and 56 RBI, while Byron Buxton and Brooks Lee have combined for 214 hits and 129 RBI.

Joe Ryan gets the ball for the Minnesota Twins, and he is 13-7 with a 3.08 ERA and 174 strikeouts this season. Ryan is 8-0 with a 1.34 ERA and 64 strikeouts in his career against the Kansas City Royals.

Kansas City Royals Betting Preview

The Kansas City Royals are 72-69 on the year and play the Guardians, Phillies, and Mariners next. The Kansas City Royals are batting .244 on the season, have a .305 OBP, and a .393 slugging percentage. The Kansas City Royals pitching staff has a 3.64 ERA and a 1.24 WHIP. Bobby Witt Jr. leads the Kansas City Royals with 160 hits and 77 RBI while Maikel Garcia and Vinnie Pasquantino have combined for 292 hits and 162 RBI.

Stephen Kolek gets the ball for the Kansas City Royals, and he is 4-5 with a 3.99 ERA and 59 strikeouts this season. This will be Kolek’s first career game against the Minnesota Twins.

Minnesota Twins @ Kansas City Royals Betting Trends: September 6, 2025

• Probable Starting Pitcher: Stephen Kolek      Record this season: 4-5      ERA: 3.99
• Home Record: 1-3
• Last 5 against Twins: –

Why the Kansas City Royals will win

• The Twins have lost each of their last six games as favorites against AL Central opponents.
• The Royals have won 23 of their last 25 home games against AL Central opponents that held a losing record.
• The Twins have failed to cover the run line in each of their last six games as favorites against AL Central opponents.
• The underdogs have covered the run line in each of the Twins’ last five games.
• The Twins have lost the first inning in three of their last four games as road favorites against AL Central opponents.
• The Twins have trailed after 5 innings in five of their last six road games.
• The Twins have trailed after 3 innings in each of their last six games as road favorites against American League opponents.

• Probable Starting Pitcher: Joe Ryan      Record this season: 13-7      ERA: 3.08
• Road Record: 6-3
• Last 5 against Royals: 3-0

Why the Minnesota Twins will win

• The Royals have lost each of their last seven games as underdogs against AL Central opponents following a win.
• The favorites have won each of the Twins’ last six games at Kauffman Stadium.
• The Royals have failed to cover the run line in each of their last seven games as underdogs against AL Central opponents following a win.
• The road team has covered the run line in seven of the Royals’ last eight games.
• The Twins have won the first inning in four of their last five road games against AL Central opponents that held a winning record.
• The Royals have trailed after 5 innings in six of their last seven games as home underdogs.

Total Runs Facts

• Each of the last eight games between the Twins and Royals at Kauffman Stadium have gone UNDER the total runs line.
• Nine of the Twins’ last 11 games have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Royals’ last five games as underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Twins’ last six night games at Kauffman Stadium.

Kansas City Royals Player Prop Facts

• Maikel Garcia has hit a home run in three of the Royals’ last four games against AL Central opponents.
• Bobby Witt Jr. has recorded a Double in three of the Royals’ last four home games against the Twins.
• Bobby Witt Jr. has recorded at least one hit in each of the Royals’ last 17 games as underdogs against the Twins.
• Bobby Witt Jr. ranks 3rd in the league in Hits (160) this season.

Minnesota Twins Player Prop Facts

• Byron Buxton has hit a home run in two of the Twins’ last three games against opponents that held a winning record.
• Byron Buxton has recorded a Double in three of his last four appearances with the Twins as favorites.
• Joe Ryan has recorded a win in eight of his 10 previous appearances against the Royals.
• Joe Ryan has recorded five or more strikeouts in each of his last nine appearances against opponents that held a winning record.
• Trevor Larnach has recorded at least one hit in each of his last seven appearances.
• Joe Ryan ranks T5th in the league for Wins (13) this season.

Matchup/League Facts

• The Royals rank 1st in the league for strikeouts against this season (954).
• The Royals rank 29th in the league for walks this season (369).
• The Twins rank 3rd in the league for walks allowed this season (394).
• The Twins rank 26th in the league for hits allowed this season (1244).

Royals vs Twins Prediction

I’m not excited to back the Twins as much as the next guy, but this simply has to do with Ryan on the mound. Not only has Ryan been great this season, but he’s owned the Royals throughout his career, which includes an 8-0 record in 10 starts. In 133 at bats against current Royals, Ryan is allowing a .180 batting average, .204 on base percentage and has 27 strikeouts. While Kolek just came over from San Diego, in 26 home innings this season, he has a 7.62 ERA and .299 allowed batting average. I’ll side with the Twins in this spot.