Royals vs White Sox Prediction 5/5/25 MLB Picks Today

In this article we will formulate a Royals vs White Sox prediction for this MLB game on Monday, May 5th at Kauffman Stadium in Kansas City, Missouri. Let’s take a look at the prediction for this MLB matchup. 

Kansas City Royals Betting Preview

The Kansas City Royals are 19-16 this year after they won two out of three against the Orioles by scores of 0-3, 4-0, and 11-6. In their game three win, Kansas City trailed 5-4 in the fifth inning, but they scored the next five runs to pull away with the win. The Royals recorded 17 hits in the game and they were led by Witt Jr., Garcia, Massey, and Waters, who all had two RBIs in the win. KC started Lorenzen, who allowed seven hits and five earned runs over 4.2 innings, while Zerpa allowed three hits and one earned run in relief, but did get the win. 

Prior to that series, the Royals won all three against the Rays and two out of three against the Astros. Kansas City has won 11 of their last 13 games and they are currently third in the AL Central standings. The Kansas City pitching staff has a 3.16 ERA with a 1.20 WHIP and a .229 opponent batting average, while the offense has scored 120 runs with a .237 batting average and a .297 on base percentage this season. Vinnie Pasquantino has led KC with six home runs and 22 RBIs, while Salvador Perez has added two home runs and 16 RBIs this year. The projected starting pitcher for Kansas City is Cole Ragans, who is 1-1 with a 4.40 ERA and a 1.17 WHIP over 30.2 innings pitched this year. 

Chicago White Sox Betting Preview

The Chicago White Sox are 10-24 this season after they won two out of three against Houston by scores of 7-3, 3-8, and 5-4. In their game three win, Chicago trailed 4-0 in the fifth, but they scored the next five runs, before the game was stopped in the seventh due to weather. The White Sox recorded seven hits in the game and they were led by Sosa, who went 1-2 with two RBIs in the win. Chicago started Wilson, who allowed nine hits and four earned runs over 4.2 innings, while Vasil allowed zero hits and zero earned runs in 2.1 innings for the win. 

Prior to that series, the White Sox lost two out of three against the Brewers and two out of three against the Athletics. Chicago has won three of their last four games and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.16 ERA with a 1.37 WHIP and a .241 opponent batting average, while the offense has scored 119 runs with a .215 batting average and a .294 on base percentage this season. Luis Robert has led Chicago with five home runs and 15 RBIs, while Andrew Benintendi has added five home runs and 12 RBIs this year. The projected starting pitcher for Chicago is Shane Smith, who is 1-1 with a 2.23 ERA and a 1.08 WHIP over 32.1 innings pitched this season. 

Why the Royals will beat the White Sox

• The White Sox have lost each of their last 17 night games against AL Central opponents.
• The Royals have won 15 of their last 16 home games against AL Central opponents that held a losing record.
• The Royals have covered the run line each of their last nine Monday games against teams that held a losing record.
• The White Sox have failed to cover the run line in each of their last six road games against the Royals following a win.
• The White Sox have lost the first inning in three of their last four night games at Kauffman Stadium.
• The White Sox have trailed after 3 innings in four of their last five road night games.
• The White Sox have trailed after 5 innings in each of their last five night games against AL Central opponents that held a winning record.

Total Runs Facts

• Each of the last six games between the White Sox and Royals at Kauffman Stadium have gone UNDER the total runs line.
• Each of the White Sox’s last five night games as underdogs have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the White Sox’s last 11 Monday games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last four night games between the White Sox and Royals.

Kansas City Royals Player Prop Facts

• Bobby Witt Jr. has recorded a Double in five of the Royals’ last six home games against AL opponents.
• Bobby Witt Jr. has scored at least one run in each of the Royals’ last six games against the White Sox.
• Bobby Witt Jr. has recorded at least one Single in each of the Royals’ last eight games against the White Sox.
• MJ Melendez has hit a home run in three of his last four home appearances against the White Sox.
• Hunter Renfroe has recorded a hit in each of his last nine appearances against the White Sox after playing the previous day.
• Hunter Renfroe has recorded at least one RBI in eight of his last nine appearances with the Royals as favorites against the White Sox.
• Bobby Witt Jr. ranks T7th in the league in Steals (9) this season.

Chicago White Sox Player Prop Facts

• Luis Robert has recorded a Double in four of his last five road appearances against the Royals after playing the previous day.
• Luis Robert has recorded an RBI in four of the White Sox’s last five games against AL opponents.
• Andrew Vaughn has recorded at least one hit in each of his last 10 Monday appearances with the White Sox as underdogs.
• Andrew Benintendi has hit a home run in two of his last three road appearances against AL Central opponents that held a winning record.
• Andrew Benintendi has recorded at least one Single in each of his last nine Monday night appearances at Kauffman Stadium.
• Andrew Benintendi has scored a run in each of his last five appearances.
• Luis Robert ranks 1st in the league in Steals (15) this season.

Matchup/League Facts

• The Royals rank T28th in the league for home runs this season (25).
• The Royals rank 3rd in the league for strikeouts against this season (247).
• The White Sox rank 30th in the league for slugging percentage this season (.328).
• The White Sox rank 28th in the league for hits this season (237).

Royals vs White Sox Prediction 

Kansas City comes into this matchup after winning a series against Baltimore over the weekend and they have been red hot over the last two weeks. The Royals are 11-5 at home this year, while the White Sox are just 3-13 on the road. Chicago has won three of their last four games and they are starting Smith, who has allowed a total of one earned run in his last two starts. The Royals are starting Ragans, who has allowed nine earned runs and nine hits over his last two starts (7.0 IP). I am tempted to take Chicago with how well Smith is pitching, but I expect a bounce back effort from Ragans and KC has been great at home. Take the Royals -1.5 here.