San Diego Padres vs Athletics Prediction 5/24/26 MLB Picks Today

The Athletics and the San Diego Padres meet Sunday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Athletics vs. San Diego Padres prediction.

Starting Pitching Matchup

The Athletics will send out Luis Medina here and Medina is 1-1 with a 2.41 ERA and 18 strikeouts this season. This will be Medina’s first career start against the Padres. Michael King will get the start for the Padres and is 4-2 with a 2.31 ERA and 59 strikeouts this season.

Athletics Recap

The Athletics come into this game looking to bounce back from a 2-0 loss at the hands of the Padres on Saturday to fall to 26-26 this season. After this series, the Athletics will head home for a series against the Seattle Mariners.

Athletics Drop Back-To-Back Games

hea Langeliers has 59 hits with 11 doubles, 12 home runs and 27 RBIs while Tyler Soderstrom’s added 35 hits with 14 doubles, a triple, 5 home runs and 23 RBIs. Brent Rooker has 27 hits with 7 home runs and 24 RBIs while Max Muncy has also chipped in 22 hits with 5 doubles, 2 triples, 2 home runs and 7 RBIs this season. Jacob Wilson also has 47 hits with 8 doubles, 3 home runs and 19 RBIs and Nick Kurtz has 49 hits with 10 doubles, 8 home runs and 36 RBIs this season.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to Saturday’s win over the Athletics to sit at 31-20 this season. After this series, the Padres will head home for a series against the Phillies.

Padres Pushing For Sweep

Jackson Merrill has 36 hits with 9 doubles, 4 home runs and 19 RBIs while Ramon Laureano has 34 hits with 5 doubles, 2 triples, 5 home runs and 19 RBIs as well on the year. Fernando Tatis Jr. has 43 hits with 5 doubles and 15 RBIs and Xander Bogaerts has 43 hits with 3 doubles, 7 home runs and 23 RBIs. Manny Machado also has 30 hits with 5 doubles, 7 home runs and 22 RBIs as well on the year.

Athletics @ San Diego Padres Betting Trends: May 24, 2026

• Probable Starting Pitcher: Michael King      Record this season: 4-2      ERA: 2.31
• Home Record: 2-1
• Last 5 against Athletics: 1-0

Why the San Diego Padres will win

• The Padres have won each of their last seven games against AL West opponents.
• The Athletics have lost each of their last seven road games against NL West opponents.
• The Padres have covered the run line in seven of their last eight games.
• The Athletics have failed to cover the run line in each of their last four games against National League opponents.
• The Padres have led after 5 innings in each of their last six day games against American League opponents.
• The Athletics have trailed after 3 innings in four of their last five day games against NL West opponents.

• Probable Starting Pitcher: Luis Medina      Record this season: 1-1      ERA: 2.41
• Road Record: 0-1
• Last 5 against Padres: 0-0

Why the Athletics will win

• The Athletics have won 11 of their last 12 games as underdogs following a loss.
• The Padres have lost four of their last five games as favorites following a win.
• The Padres have failed to cover the run line in each of their last eight games as favorites following a win.
• The Athletics have covered the run line in 11 of their last 12 games as underdogs following a loss.
• The Athletics have led after 3 innings in each of their last four day games against opponents that held a winning record.
• The Athletics have led after 5 innings in five of their last six road day games.
• The Athletics have won the first inning in three of their last four day games against opponents that held a winning record.

Total Runs Facts

• Nine of the Padres’ last 10 home games after playing the previous day have gone UNDER the total runs line.
• Each of the Athletics’ last four games as underdogs against the Padres have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in nine of the Padres’ last 10 home games against American League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Athletics’ last four games as underdogs against NL West opponents.

San Diego Padres Player Prop Facts

• Nick Castellanos has hit a home run in each of the Padres’ last two games as favorites.
• Miguel Andujar has recorded at least one hit in each of his last 11 appearances with his team as a home favorite against AL West opponents.
• Fernando Tatis Jr. ranks T9th in the league in Steals (12) this season.

Athletics Player Prop Facts

• Zack Gelof has hit a home run in each of the Athletics’ last two day games against opponents that held a winning record.
• Nick Kurtz has recorded at least one hit in each of the Athletics’ last nine games against opponents that held a winning record.
• Nick Kurtz ranks 1st amongst qualified players for On Base Percentage (.444) this season.

Matchup/League Facts

• The Padres rank 30th in the league for hits this season (363).
• The Padres rank 30th in the league for batting average this season (.219).
• The Athletics rank T5th in the league for hits this season (438).
• The Athletics rank 5th in the league for batting average this season (.248).

Athletics vs. San Diego Padres Prediction

I’m on the Padres in this one. I get the case to be made for either side in this game, but the Athletics have struggled in lesser spots in this series and now face this season’s ace so far for the Padres with Michael King going and King’s been lights out for much of the season. I think the Padres finish off the sweep so give me San Diego here.