Padres vs Rockies Prediction 9/12/25 MLB Picks Today

The Colorado Rockies and the San Diego Padres meet Friday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Padres vs Rockies Prediction.

Starting Pitching Matchup

The Colorado Rockies will start Tanner Gordon here and Gordon is 5-6 with a 6.60 ERA and 46 strikeouts this season. In his career, Gordon is 0-1 with a 6.52 ERA and 9 strikeouts against the Padres. The San Diego Padres did not have a starting pitcher announced at the time that this article was posted.

Colorado Rockies Recap

The Colorado Rockies come into this game looking to bounce back from their 2-0 loss at the hands of the Padres on Thursday to sit at 40-107 this season. After this series, the Rockies will head back to Coors Field for a series with the Miami Marlins.

Rockies Lose 6th Straight

Hunter Goodman leads the Rockies with 133 hits including 25 doubles, 4 triples, 29 home runs and 86 RBIs while Michael Toglia has 58 hits with 15 doubles, 11 home runs and 32 RBIs but also has 126 strikeouts. Kyle Farmer has 14 doubles while Jordan Beck has 15 home runs, 25 doubles, 50 RBIs, 5 triples and 16 stolen bases. Brenton Doyle has 110 hits with 20 doubles, 14 home runs, 55 RBIs and 16 stolen bases. Mickey Moniak has 100 hits with 17 doubles, 8 triples and 19 home runs with 57 RBIs. 

Why the Colorado Rockies will win

• The Padres have lost five of their last seven games as home favorites.
• The Padres have failed to cover the run line in seven of their last eight home games.
• The underdogs have covered the run line in six of the Padres’ last seven games at Petco Park.

Colorado Rockies Player Prop Facts

• Thairo Estrada has recorded at least one hit in each of his last nine appearances at Petco Park.
• Brenton Doyle has hit a home run in six of the Rockies’ last 22 games against NL West opponents.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to their win over the Rockies last time out to sit at 80-67 this season. After this series, the Padres will take to the road for a set against the New York Mets.

Padres Snap Two-Game Skid

Manny Machado has 155 hits including a team-high 33 doubles, 23 home runs, 84 RBIs and 13 stolen bases while Fernando Tatis Jr. has 143 hits with 21 home runs and 63 RBIs along with 29 stolen bases of his own this season. Luis Arraez has added 159 hits with 29 doubles, 4 triples, 7 home runs and 54 RBIs while Jackson Merrill’s added 98 hits with 10 home runs and 55 RBIs as well. Xander Bogaerts also has 29 doubles and 20 stolen bases as well this season. Gavin Sheets also has 26 doubles, 19 home runs and 64 RBIs as well this season.

Why the San Diego Padres will win

• The Rockies have lost each of their last 12 night games after playing the previous day.
• The Padres have won each of their last six home games against the Rockies.
• The Rockies have failed to cover the run line in each of their last nine games after playing the previous day.
• The favorites have covered the run line in each of the Rockies’ last six games.

San Diego Padres Player Prop Facts

• Jackson Merrill has hit a home run in each of the Padres’ last two games against the Rockies.
• JP Sears has recorded five or more strikeouts in four of his last five home appearances.
• Fernando Tatis Jr. has recorded at least one hit in each of his last 12 Friday appearances against NL West teams that held a losing record.
• JP Sears has recorded a win in six of his last seven appearances with his team as a home favorite .
• Xander Bogaerts has recorded a Double in three of his last four appearances in night games against teams that held a losing record.
• Luis Arraez ranks 4th in the league in Hits (162) this season.

Total Runs Facts

• Fourteen of the Padres’ last 16 night games against National League opponents have gone UNDER the total runs line.
• Seven of the Rockies’ last nine road games have gone UNDER the total runs line.

Padres vs Rockies Prediction

I’m on the Padres here. It’s not a spot to find some value as the Padres are such heavy favorites, but Tanner Gordon’s been getting hit hard, and I just don’t trust the Rockies to keep themselves in this game offensively. I’ll side with the Padres in this one.